Q5L5X3 (SURE_CHLAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
5'-nucleotidase surE
EC=3.1.3.5

Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase

Gene names

Name:	surE
Ordered Locus Names:	CAB506

Organism

Chlamydophila abortus [Complete proteome] [HAMAP]

Taxonomic identifier

83555 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydophila

Protein attributes

Sequence length	278 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential HAMAP MF_00060.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 278	278	5'-nucleotidase surE HAMAP MF_00060		PRO_0000235605
Sites
	Metal binding	12	1	Divalent metal cation By similarity
	Metal binding	13	1	Divalent metal cation By similarity
	Metal binding	45	1	Divalent metal cation By similarity
	Metal binding	103	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q5L5X3 [UniParc]. Last modified June 21, 2005. Version 1. Checksum: EC454F4A657A8AB8	FASTA	278	30,322
	10 20 30 40 50 60 MHRRLKILLT NDDGISAKGM SLLVANLLKA DFADLYIVAP ATEQSGKSMS FSYTQPVSIE 70 80 90 100 110 120 KVDYPQPVAG AWAVSGSPVD CVKLALGDLF RNALPDLVLS GINHGSNAGR NIFYSGTAGA 130 140 150 160 170 180 AMEAILSGVP SIAFSQEQHI SFFQEVHAPE ILKKLSLYAL SMPFPILSGF NVNFPASERN 190 200 210 220 230 240 EEWKGMRLVT TGKEYACGMP KLLVDDGKRK FFSLSDCQIV MDEDISDECR TLLENYITVV 250 260 270 PLLVRNSPLA LISETKFQQL QEAFDNFISS ASGATLLD

References

[1]

"The Chlamydophila abortus genome sequence reveals an array of variable proteins that contribute to interspecies variation." Thomson N.R., Yeats C., Bell K., Holden M.T.G., Bentley S.D., Livingstone M., Cerdeno-Tarraga A.-M., Harris B., Doggett J., Ormond D., Mungall K., Clarke K., Feltwell T., Hance Z., Sanders M., Quail M.A., Price C., Barrell B.G., Parkhill J., Longbottom D. Genome Res. 15:629-640(2005) [PubMed: 15837807] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S26/3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR848038 Genomic DNA. Translation: CAH63958.1.
RefSeq	YP_219919.1. NC_004552.2.
3D structure databases
ProteinModelPortal	Q5L5X3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3337798.
GenomeReviews	Gene locus CAB506 in contig CR848038_GR.
KEGG	cab:CAB506.
PATRIC	20202495. VBIChlAbo21869_0561.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG600532.
OMA	SNAGRNI.
PhylomeDB	Q5L5X3.
ProtClustDB	PRK00346.
Enzyme and pathway databases
BioCyc	CABO218497:CAB506-MONOMER.
Family and domain databases
HAMAP	MF_00060. SurE. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KO	K03787.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
SUPFAM	SSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMs	TIGR00087. SurE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE_CHLAB

Accession

Primary (citable) accession number: Q5L5X3

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 16, 2006
Last sequence update:	June 21, 2005
Last modified:	January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program