Q5L5V3 (GCP_CHLAB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	CAB528

Organism

Chlamydophila abortus [Complete proteome] [HAMAP]

Taxonomic identifier

83555 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydophila

Protein attributes

Sequence length	344 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 344	344	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303319

Sequences

	Sequence		Length	Mass (Da)
	Q5L5V3 [UniParc]. Last modified June 21, 2005. Version 1. Checksum: 695A248D9050D37B	FASTA	344	36,544
	10 20 30 40 50 60 MLTLGLESSC DETACALVDA NAKIVANVVF SQQDHVSYGG IVPELASRAH LQVFPSVVQS 70 80 90 100 110 120 ALKESGVSLE DIDLFAVTHT PGLIGALAIG VNFAKGLAVG CQKPIIGVNH VEAHLYAAYM 130 140 150 160 170 180 EASSVEFPAL GLVVSGAHTA IFLMEDPLTY KLIGKSRDDA IGETFDKVAR FLGLPYPGGA 190 200 210 220 230 240 LIEKLAVHGC ESSYPFSPSK VPGYDLSFSG LKTAVLYAIK GNNSNHRTPL PELSESQKNN 250 260 270 280 290 300 ISASFQKAAF TSVAQKLPNI VKKFSCRSLL VGGGVANNKY FQSLLKNTLD LPLYFPSSKL 310 320 330 340 CTDNAAMIAG LGRELFLSEK ITSGITPCAR YQWESASVSL SPLP

References

[1]

"The Chlamydophila abortus genome sequence reveals an array of variable proteins that contribute to interspecies variation." Thomson N.R., Yeats C., Bell K., Holden M.T.G., Bentley S.D., Livingstone M., Cerdeno-Tarraga A.-M., Harris B., Doggett J., Ormond D., Mungall K., Clarke K., Feltwell T., Hance Z., Sanders M., Quail M.A., Price C., Barrell B.G., Parkhill J., Longbottom D. Genome Res. 15:629-640(2005) [PubMed: 15837807] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S26/3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR848038 Genomic DNA. Translation: CAH63979.1.
RefSeq	YP_219939.1. NC_004552.2.
3D structure databases
ProteinModelPortal	Q5L5V3.
ModBase	Search...
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3337811.
GenomeReviews	Gene locus CAB528 in contig CR848038_GR.
KEGG	cab:CAB528.
PATRIC	20202545. VBIChlAbo21869_0584.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304663.
OMA	PAVGVHH.
PhylomeDB	Q5L5V3.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	CABO218497:CAB528-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_CHLAB

Accession

Primary (citable) accession number: Q5L5V3

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	June 21, 2005
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program