Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5L5Q6

- SYL_CHLAB

UniProt

Q5L5Q6 - SYL_CHLAB

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Leucine--tRNA ligase

Gene

leuS

Organism
Chlamydophila abortus (strain DSM 27085 / S26/3)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei604 – 6041ATPUniRule annotation

GO - Molecular functioni

  1. aminoacyl-tRNA editing activity Source: InterPro
  2. ATP binding Source: UniProtKB-HAMAP
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCABO218497:GJB0-601-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligaseUniRule annotation (EC:6.1.1.4UniRule annotation)
Alternative name(s):
Leucyl-tRNA synthetaseUniRule annotation
Short name:
LeuRSUniRule annotation
Gene namesi
Name:leuSUniRule annotation
Ordered Locus Names:CAB585
OrganismiChlamydophila abortus (strain DSM 27085 / S26/3)
Taxonomic identifieri218497 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydophila
ProteomesiUP000001012: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 820820Leucine--tRNA ligasePRO_1000009319Add
BLAST

Proteomic databases

PRIDEiQ5L5Q6.

Interactioni

Protein-protein interaction databases

STRINGi218497.CAB585.

Structurei

3D structure databases

ProteinModelPortaliQ5L5Q6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi40 – 5112"HIGH" regionAdd
BLAST
Motifi601 – 6055"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200748.
KOiK01869.
OMAiERYWMNV.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR015413. Methionyl/Leucyl_tRNA_Synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 1 hit.
PF13603. tRNA-synt_1_2. 1 hit.
PF09334. tRNA-synt_1g. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5L5Q6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRYDPSLIEK KWQQFWKEHK SFKADETADK PKYYVLDMFP YPSGAGLHVG
60 70 80 90 100
HLIGYTATDI VARYKRAKGF SVLHPMGWDS FGLPAEQYAV RTGTHPRETT
110 120 130 140 150
KKNIENFRKQ LSAMGFSYDE AREFATSDPE YYRWTQKLFL FLYEKGLAYM
160 170 180 190 200
ADMAVNYCEE LGTVLANEEV ENGLSIEGGY PVERRMLRQW ILRITAYADQ
210 220 230 240 250
LLQGLEDLDW PENVKQLQRN WIGKSEGALL RFVVDKDKCL EVFTTRPDTL
260 270 280 290 300
CGVSFLVMAP EHPEIQQLVS EEQRSAVESY IRCAQSKSER ERISETKVKS
310 320 330 340 350
GVFTGAYAKH AITGAALPIW VSDYVIMGYG SGVVMGVPAH DERDREFANA
360 370 380 390 400
FALPIDEVLD ENEHCINSNH GDFLLNGLQG KEASDYVIAY LQKRNLGEAK
410 420 430 440 450
VMYKLHDWLF SRQRYWGEPI PIIHFEDGTC RPLEDDELPL LPPEIQDYRP
460 470 480 490 500
KGFGQGPLAK VKEWVDIHDV KTQRPGRRET HTMPQWAGSC WYYLRFCDAH
510 520 530 540 550
NSQAPWSHEN ERYWMPVDLY IGGAEHAVLH LLYSRFWHRV FYEAGLVSTP
560 570 580 590 600
EPFKKLINQG LVLATSYRIP GKGYVHPEDA REDNGKWTTA SGEELEVRQE
610 620 630 640 650
KMSKSKLNGV DPQILIDEFG ADALRMYAMF SGPLDKNKLW CNQGVSGCRR
660 670 680 690 700
FLNRFYELAT SSAVQDIDDP KGMALAHRLV HKVGEDIEKM SLNTIPSSFM
710 720 730 740 750
EFINEFAKLD TYSKSALSMV VRALAPIAPH ISEELWTVLG YAPGIDNAGW
760 770 780 790 800
PEVDPKYLED TSVTFVIQVN GKLRARLDMD KNTSQEDILS AARESVAKYL
810 820
EDKEIKKEVF VPNRLVNFVL
Length:820
Mass (Da):93,863
Last modified:June 21, 2005 - v1
Checksum:i8FD3378BD6A2FBF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR848038 Genomic DNA. Translation: CAH64033.1.
RefSeqiWP_011097182.1. NC_004552.2.
YP_219986.1. NC_004552.2.

Genome annotation databases

EnsemblBacteriaiCAH64033; CAH64033; CAB585.
GeneIDi3337448.
KEGGicab:CAB585.
PATRICi20202673. VBIChlAbo21869_0644.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR848038 Genomic DNA. Translation: CAH64033.1 .
RefSeqi WP_011097182.1. NC_004552.2.
YP_219986.1. NC_004552.2.

3D structure databases

ProteinModelPortali Q5L5Q6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 218497.CAB585.

Proteomic databases

PRIDEi Q5L5Q6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAH64033 ; CAH64033 ; CAB585 .
GeneIDi 3337448.
KEGGi cab:CAB585.
PATRICi 20202673. VBIChlAbo21869_0644.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200748.
KOi K01869.
OMAi ERYWMNV.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci CABO218497:GJB0-601-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR015413. Methionyl/Leucyl_tRNA_Synth.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 1 hit.
PF13603. tRNA-synt_1_2. 1 hit.
PF09334. tRNA-synt_1g. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 27085 / S26/3.

Entry informationi

Entry nameiSYL_CHLAB
AccessioniPrimary (citable) accession number: Q5L5Q6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: June 21, 2005
Last modified: November 26, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3