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Q5L5J7 (PKND_CHLAB) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase PknD

EC=2.7.11.1
Gene names
Name:pknD
Ordered Locus Names:CAB647
OrganismChlamydophila abortus (strain DSM 27085 / S26/3) [Complete proteome] [HAMAP]
Taxonomic identifier218497 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydophila

Protein attributes

Sequence length933 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth By similarity. HAMAP-Rule MF_01957

Catalytic activity

ATP + a protein = ADP + a phosphoprotein. HAMAP-Rule MF_01957

Post-translational modification

Autophosphorylated on serine and threonine residues By similarity. HAMAP-Rule MF_01957

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 933933Serine/threonine-protein kinase PknD HAMAP-Rule MF_01957
PRO_0000239300

Regions

Domain4 – 291288Protein kinase
Nucleotide binding10 – 189ATP By similarity

Sites

Active site1381Proton acceptor By similarity
Binding site331ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5L5J7 [UniParc].

Last modified June 21, 2005. Version 1.
Checksum: FF1C265A91BE1A29

FASTA933106,836
        10         20         30         40         50         60 
MQHYDIIRMI GKGGMGEVYL AYDPICSRKV ALKRIREDLS DNELLKKRFL REAKIAADLV 

        70         80         90        100        110        120 
HPGVVPVFTI CSDSDLVYYT MPYIEGYTLK SLLKSVWQCD SLPKDLAEQT SVGTFLSIFH 

       130        140        150        160        170        180 
KICSTIEYVH SRGILHRDLK PDNILLGLFS EVVILDWGAA LSKEMKEDVL LDLDIPMPGS 

       190        200        210        220        230        240 
MFSNMTVPGK IVGTPDYMAP ERLRGAPASE STDIYALGVI LYQMLTLSFP YRNKKGKKIH 

       250        260        270        280        290        300 
VPNHIISPEE VAPHREIPSF LSQVVMRALA TDPKERYTSV QALKADIEQH LQGSPQWTPK 

       310        320        330        340        350        360 
IALHTQDAEC WKFHESILLS KYFPMLEVSP ALWYSLAISK IESFSEVRLE YTLLRKGLEG 

       370        380        390        400        410        420 
GFGILLPPSE NVDHGDFYRG YGFWLHIKKN VLSVSLVRNG LEIQKTSGNI DVNQEKFFIA 

       430        440        450        460        470        480 
FEKQNHRLSL NIDHTVWMIH MDYLPGRGGR IGVIIQDITD VCGNIVVLES SGALHVSCLA 

       490        500        510        520        530        540 
VPDAFLNEKL YDRAITFYRR IVESFPGRKE GYEAQFRIGI AVLEKAAEEG DQEGFSQALR 

       550        560        570        580        590        600 
EFSVLHDSVA APLEYLGKAL VYQRLEEYNE EVKSLLLALK RYGQRPEISR VRDHVVDRLH 

       610        620        630        640        650        660 
EALYSNHRVS LVFMLLALHV APESINSSEE EHFLKNLQGK IHDTLFCSLD ISPIDFRSSK 

       670        680        690        700        710        720 
MELLLSYWSG FTPFLPGLFQ RSWDLKDYRA LADIFYTAAD LGEREFIDVY GNTLRENIQA 

       730        740        750        760        770        780 
TTFTEDIVEI FPHQLIHFLS ALDAIFLHAP VEKIFSDVDI LDPVLIIYLF DLFAKDVLIH 

       790        800        810        820        830        840 
GKGEQILDAI QVLETYVSPQ QRHTYLLPYE ILAYLWMKEG KKVHELLSAH YDESFWIEDS 

       850        860        870        880        890        900 
HWAFVLYGYW LALTEESSLA YLHLSGCRED HVAPRALIGL FCSPLGICEN QWSYQERRNL 

       910        920        930 
LLQKFIFFHC LGDDVERDNC RVAYDLLVKE RLL 

« Hide

References

[1]"The Chlamydophila abortus genome sequence reveals an array of variable proteins that contribute to interspecies variation."
Thomson N.R., Yeats C., Bell K., Holden M.T.G., Bentley S.D., Livingstone M., Cerdeno-Tarraga A.-M., Harris B., Doggett J., Ormond D., Mungall K., Clarke K., Feltwell T., Hance Z., Sanders M., Quail M.A., Price C., Barrell B.G., Parkhill J., Longbottom D.
Genome Res. 15:629-640(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 27085 / S26/3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR848038 Genomic DNA. Translation: CAH64094.1.
RefSeqYP_220045.1. NC_004552.2.

3D structure databases

ProteinModelPortalQ5L5J7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING218497.CAB647.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAH64094; CAH64094; CAB647.
GeneID3337290.
KEGGcab:CAB647.
PATRIC20202809. VBIChlAbo21869_0711.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000034686.
KOK08884.
OMAYQMLTLS.
OrthoDBEOG6W45P7.
ProtClustDBPRK13184.

Enzyme and pathway databases

BioCycCABO218497:GJB0-664-MONOMER.

Family and domain databases

HAMAPMF_01957. PknD_kinase.
InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR023507. Ser/Thr_kinase_PknD.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKND_CHLAB
AccessionPrimary (citable) accession number: Q5L5J7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: June 21, 2005
Last modified: February 19, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families