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Protein

DNA replication and repair protein RecF

Gene

recF

Organism
Geobacillus kaustophilus (strain HTA426)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi30 – 378ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair, DNA replication, SOS response

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciGKAU235909:GJO7-4-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA replication and repair protein RecFUniRule annotation
Gene namesi
Name:recFUniRule annotation
Ordered Locus Names:GK0004
OrganismiGeobacillus kaustophilus (strain HTA426)
Taxonomic identifieri235909 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus
Proteomesi
  • UP000001172 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 372372DNA replication and repair protein RecFPRO_0000236118Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi235909.GK0004.

Structurei

3D structure databases

ProteinModelPortaliQ5L3Y9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecF family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C3X. Bacteria.
COG1195. LUCA.
HOGENOMiHOG000269559.
KOiK03629.
OMAiKVQTFIT.
OrthoDBiEOG6HTP3X.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PANTHERiPTHR32182:SF0. PTHR32182:SF0. 1 hit.
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00617. RECF_1. 1 hit.
PS00618. RECF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5L3Y9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLTNLTLTN YRNYEYETLN FGEGVNVILG ENAQGKTNMM EAIYVLAMAK
60 70 80 90 100
SHRTSNDKDL IRWNEEYAKI EGRAEKRSGS LTLELLISKK GKKARCNHIE
110 120 130 140 150
QQRLSQYVGH LNVVMFAPED LNLVKGSPQV RRRFVDMEIG QVSPVYIHDL
160 170 180 190 200
SQYQKLLQQR NHYLKMMQAR ERSDEAVLDV LTEQLVLLAA KITLRRRQFL
210 220 230 240 250
SLLEQWAMPI HYEISRGAEQ LCIRYEPSVD VSEKAELSRI VEAYSETFAA
260 270 280 290 300
MREREVQRGT TLVGPHRDDI AFFVNGKNVQ TFGSQGQQRT TALAVKLAEL
310 320 330 340 350
ELIFSELGDY PILLLDDVLS ELDDFRQTHL LDAIRKKVQT FVTTTSIDGI
360 370
KHDIIQEAAI YRVHSGSVTA PS
Length:372
Mass (Da):42,583
Last modified:February 1, 2005 - v1
Checksum:i6774A104EA3445F8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000043 Genomic DNA. Translation: BAD74289.1.
RefSeqiWP_011229520.1. NC_006510.1.

Genome annotation databases

EnsemblBacteriaiBAD74289; BAD74289; GK0004.
GeneIDi3184840.
KEGGigka:GK0004.
PATRICi21961003. VBIGeoKau81518_0049.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000043 Genomic DNA. Translation: BAD74289.1.
RefSeqiWP_011229520.1. NC_006510.1.

3D structure databases

ProteinModelPortaliQ5L3Y9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi235909.GK0004.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD74289; BAD74289; GK0004.
GeneIDi3184840.
KEGGigka:GK0004.
PATRICi21961003. VBIGeoKau81518_0049.

Phylogenomic databases

eggNOGiENOG4105C3X. Bacteria.
COG1195. LUCA.
HOGENOMiHOG000269559.
KOiK03629.
OMAiKVQTFIT.
OrthoDBiEOG6HTP3X.

Enzyme and pathway databases

BioCyciGKAU235909:GJO7-4-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00365. RecF.
InterProiIPR001238. DNA-binding_RecF.
IPR018078. DNA-binding_RecF_CS.
IPR027417. P-loop_NTPase.
IPR003395. RecF/RecN/SMC_N.
[Graphical view]
PANTHERiPTHR32182:SF0. PTHR32182:SF0. 1 hit.
PfamiPF02463. SMC_N. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
TIGRFAMsiTIGR00611. recf. 1 hit.
PROSITEiPS00617. RECF_1. 1 hit.
PS00618. RECF_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Thermoadaptation trait revealed by the genome sequence of thermophilic Geobacillus kaustophilus."
    Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H., Matsui S., Uchiyama I.
    Nucleic Acids Res. 32:6292-6303(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HTA426.

Entry informationi

Entry nameiRECF_GEOKA
AccessioniPrimary (citable) accession number: Q5L3Y9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: February 1, 2005
Last modified: April 13, 2016
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.