Cysteine synthase - Geobacillus kaustophilus (strain HTA426)

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Q5L3S8 (Q5L3S8_GEOKA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 49. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

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Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Recommended name:
Cysteine synthase RuleBase RU003985
EC=2.5.1.47 RuleBase RU003985

Gene names

Ordered Locus Names:

GK0065

Organism

Geobacillus kaustophilus (strain HTA426) [Complete proteome] [HAMAP]

Taxonomic identifier

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length	308 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	O(3)-acetyl-L-serine + H₂S = L-cysteine + acetate. RuleBase RU003985
Sequence similarities	Belongs to the cysteine synthase/cystathionine beta-synthase family. RuleBase RU003985

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Cysteine biosynthesis RuleBase RU003985
Molecular function	Transferase RuleBase RU003985 EMBL BAD74350.1
Technical term	3D-structure PDB 2EGU Complete proteome
Gene Ontology (GO)
Biological process	cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro
Molecular function	cysteine synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q5L3S8 [UniParc].

Last modified February 1, 2005. Version 1.
Checksum: 21CFAECBA396617F
Show »

308

32,517

        10         20         30         40         50         60 
MARTVNSITE LIGDTPAVKL NRIVDEDSAD VYLKLEFMNP GSSVKDRIAL AMIEAAEKAG 

        70         80         90        100        110        120 
KLKPGDTIVE PTSGNTGIGL AMVAAAKGYK AVLVMPDTMS LERRNLLRAY GAELVLTPGA 

       130        140        150        160        170        180 
QGMRGAIAKA EELVREHGYF MPQQFKNEAN PEIHRLTTGK EIVEQMGDQL DAFVAGVGTG 

       190        200        210        220        230        240 
GTITGAGKVL REAYPNIKIY AVEPADSPVL SGGKPGPHKI QGIGAGFVPD ILDTSIYDGV 

       250        260        270        280        290        300 
ITVTTEEAFA AARRAAREEG ILGGISSGAA IHAALKVAKE LGKGKKVLAI IPSNGERYLS 


TPLYQFED

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Thermoadaptation trait revealed by the genome sequence of thermophilic Geobacillus kaustophilus." Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H., Matsui S., Uchiyama I. Nucleic Acids Res. 32:6292-6303(2004) [PubMed: 15576355] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HTA426.
[2]	"Crystal structure of O-acetylserine sulfhydrase from Geobacillus kaustophilus HTA426." Rehse P.H., Yokoyama S. Submitted (MAR-2007) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

BA000043 Genomic DNA. Translation: BAD74350.1.

RefSeq

YP_145918.1. NC_006510.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2EGU	X-ray	1.90	A	1-308	[»]

ProteinModelPortal

SMR

Q5L3S8. Positions 1-308.

ModBase

Protocols and materials databases

StructuralBiologyKnowledgebase

Genome annotation databases

GeneID

GenomeReviews

Gene locus GK0065 in contig BA000043_GR.

KEGG

NMPDR

fig|235909.3.peg.91.

PATRIC

21961161. VBIGeoKau81518_0116.

Organism-specific databases

CMR

Phylogenomic databases

HOGENOM

OMA

ProtClustDB

Family and domain databases

InterPro

IPR001216. Cys_synth_BS.
IPR005856. Cys_synthKM.
IPR005859. CysK.
IPR001926. PyrdxlP-dep_enz_bsu.
[Graphical view]

KO

Pfam

PF00291. PALP. 1 hit.
[Graphical view]

SUPFAM

SSF53686. PyrdxlP-dep_enz_bsu. 1 hit.

TIGRFAMs

TIGR01139. CysK. 1 hit.
TIGR01136. CysKM. 1 hit.

PROSITE

PS00901. CYS_SYNTHASE. 1 hit.
[Graphical view]

ProtoNet

Entry information

Entry name

Q5L3S8_GEOKA

Accession

Primary (citable) accession number: Q5L3S8

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 2005
Last sequence update:	February 1, 2005
Last modified:	December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

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Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info