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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Geobacillus kaustophilus (strain HTA426)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei38NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:GK1266
OrganismiGeobacillus kaustophilus (strain HTA426)
Taxonomic identifieri235909 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus
Proteomesi
  • UP000001172 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001218381 – 285tRNA pseudouridine synthase BAdd BLAST285

Interactioni

Protein-protein interaction databases

STRINGi235909.GK1266.

Structurei

3D structure databases

ProteinModelPortaliQ5L0I5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
HOGENOMiHOG000231225.
KOiK03177.
OMAiYELQFIR.
OrthoDBiPOG091H02G9.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR032819. TruB_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5L0I5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGVLLLNKP KGMTSHDCVA KVRRLLGVKK AGHTGTLDPN VSGVLPICLG
60 70 80 90 100
KATRIAEFLT GTTKTYEGKV TLGAATTTED ADGDIIAARP VDRPIARAEI
110 120 130 140 150
EAVFDSLTGE IEQTPPMYSA VKVGGKKLYE YARAGIEVER PTRRVTIYEL
160 170 180 190 200
ELLDEREQFF GETVSFRFRV TCSKGTYVRT LAVMIGERLG YPAHMSDLIR
210 220 230 240 250
TASGPFRLED CVTFEDVERR AADGTADALL IPIERALFHL PKYEINDKVA
260 270 280
EKVKNGALLR LPAFLEKLTG RSCLFRPSGK RWPCT
Length:285
Mass (Da):31,436
Last modified:February 1, 2005 - v1
Checksum:i68EC08DAD8B5EC5F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000043 Genomic DNA. Translation: BAD75551.1.
RefSeqiWP_011230766.1. NC_006510.1.

Genome annotation databases

EnsemblBacteriaiBAD75551; BAD75551; GK1266.
GeneIDi3185349.
KEGGigka:GK1266.
PATRICi21963796. VBIGeoKau81518_1367.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000043 Genomic DNA. Translation: BAD75551.1.
RefSeqiWP_011230766.1. NC_006510.1.

3D structure databases

ProteinModelPortaliQ5L0I5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi235909.GK1266.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD75551; BAD75551; GK1266.
GeneIDi3185349.
KEGGigka:GK1266.
PATRICi21963796. VBIGeoKau81518_1367.

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
HOGENOMiHOG000231225.
KOiK03177.
OMAiYELQFIR.
OrthoDBiPOG091H02G9.

Family and domain databases

HAMAPiMF_01080. TruB_bact. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR032819. TruB_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTRUB_GEOKA
AccessioniPrimary (citable) accession number: Q5L0I5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: February 1, 2005
Last modified: November 2, 2016
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.