Reviewed, UniProtKB/Swiss-Prot Q5L055 (MQO_GEOKA)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor]
    MQO

Gene names

Name:	mqo
Ordered Locus Names:	GK1396

Organism

Geobacillus kaustophilus [Complete proteome] [HAMAP]

Taxonomic identifier

1462 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length	501 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor. HAMAP MF_00212
Cofactor	FAD By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle. HAMAP MF_00212
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 501	501	Probable malate:quinone oxidoreductase HAMAP MF_00212		PRO_1000023801

Sequences

	Sequence		Length	Mass (Da)
	Q5L055-1 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: C58460F1D2AC4831	FASTA	501	55,200
	10 20 30 40 50 60 MGNKQGKMDV ILIGAGIMSA TLGTLLKELA PEWDIVVFER LEEAGAESSN EWNNAGTGHA 70 80 90 100 110 120 ALCELNYTVE KADGSIDIGK AIKINEQFYV SLQFWAYLVN SGILRDPKDF VRPLPHMSFV 130 140 150 160 170 180 QGEDNVAFLK KRHETMAANP LFKGMEFTDD PKKLAEWVPL MMEGRVVDEP IAATRIESGT 190 200 210 220 230 240 DVNFGALTRQ LFEHLKRKNV EIRYRHHVED IKRTSDGLWE LKVRNLDTGT VELHAAKFVF 250 260 270 280 290 300 IGAGGGSLHL LQKSGIPEGK GIGGFPVSGL FMVCNNPEVV EQHHAKVYGK AKVGAPPMSV 310 320 330 340 350 360 PHLDTRFIDN QKMLLFGPFA GFSPKFLKNG SMLDLFTSIK PHNVLTILAA GVKNMSLTNY 370 380 390 400 410 420 LIQQVLLSKE QRMQELREFV PTAKSDEWDI VVAGQRVQVI KDTESGGKGT LQFGTEVVHA 430 440 450 460 470 480 ADGSIAALLG ASPGASTAVH VMLEVMEKCF PERMNEWRAK VKEMIPSYGE SLMKNEALLR 490 500 QVQASTAEAL GLNGHFAMQL A

References

[1]

"Thermoadaptation trait revealed by the genome sequence of thermophilic Geobacillus kaustophilus." Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H., Matsui S., Uchiyama I. Nucleic Acids Res. 32:6292-6303(2004) [PubMed: 15576355] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HTA426.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000043 Genomic DNA. Translation: BAD75681.1.
RefSeq	YP_147249.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3183755.
GenomeReviews	Gene locus GK1396 in contig BA000043_GR.
KEGG	gka:GK1396.
NMPDR	fig|235909.3.peg.245.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q5L055.
OMA	REMIPSY.
Enzyme and pathway databases
BioCyc	GKAU235909:GK1396-MON.
BRENDA	1.1.99.16. 281547.
Family and domain databases
HAMAP	MF_00212. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_GEOKA

Accession

Primary (citable) accession number: Q5L055

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 1, 2005
Last modified:	November 3, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)