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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Geobacillus kaustophilus (strain HTA426)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:GK1396
OrganismiGeobacillus kaustophilus (strain HTA426)
Taxonomic identifieri235909 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillusGeobacillus thermoleovorans group
Proteomesi
  • UP000001172 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000238011 – 501Probable malate:quinone oxidoreductaseAdd BLAST501

Proteomic databases

PRIDEiQ5L055

Interactioni

Protein-protein interaction databases

STRINGi235909.GK1396

Structurei

3D structure databases

ProteinModelPortaliQ5L055
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT Bacteria
COG0579 LUCA
HOGENOMiHOG000109379
KOiK00116
OMAiEPIAATK
OrthoDBiPOG091H0B7C

Family and domain databases

Gene3Di3.50.50.60, 2 hits
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

Q5L055-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNKQGKMDV ILIGAGIMSA TLGTLLKELA PEWDIVVFER LEEAGAESSN
60 70 80 90 100
EWNNAGTGHA ALCELNYTVE KADGSIDIGK AIKINEQFYV SLQFWAYLVN
110 120 130 140 150
SGILRDPKDF VRPLPHMSFV QGEDNVAFLK KRHETMAANP LFKGMEFTDD
160 170 180 190 200
PKKLAEWVPL MMEGRVVDEP IAATRIESGT DVNFGALTRQ LFEHLKRKNV
210 220 230 240 250
EIRYRHHVED IKRTSDGLWE LKVRNLDTGT VELHAAKFVF IGAGGGSLHL
260 270 280 290 300
LQKSGIPEGK GIGGFPVSGL FMVCNNPEVV EQHHAKVYGK AKVGAPPMSV
310 320 330 340 350
PHLDTRFIDN QKMLLFGPFA GFSPKFLKNG SMLDLFTSIK PHNVLTILAA
360 370 380 390 400
GVKNMSLTNY LIQQVLLSKE QRMQELREFV PTAKSDEWDI VVAGQRVQVI
410 420 430 440 450
KDTESGGKGT LQFGTEVVHA ADGSIAALLG ASPGASTAVH VMLEVMEKCF
460 470 480 490 500
PERMNEWRAK VKEMIPSYGE SLMKNEALLR QVQASTAEAL GLNGHFAMQL

A
Length:501
Mass (Da):55,200
Last modified:February 1, 2005 - v1
Checksum:iC58460F1D2AC4831
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000043 Genomic DNA Translation: BAD75681.1
RefSeqiWP_011230892.1, NC_006510.1

Genome annotation databases

EnsemblBacteriaiBAD75681; BAD75681; GK1396
KEGGigka:GK1396
PATRICifig|235909.7.peg.1508

Similar proteinsi

Entry informationi

Entry nameiMQO_GEOKA
AccessioniPrimary (citable) accession number: Q5L055
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 1, 2005
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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