Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot Q5KYS6 (XYLA_GEOKA)

Last modified November 3, 2009. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein namesRecommended name:
    Xylose isomerase
    EC=5.3.1.5
Gene names
Name: xylA
Ordered Locus Names: GK1875
OrganismGeobacillus kaustophilus [Complete proteome] [HAMAP]
Taxonomic identifier1462 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Geobacillus

Hide | Top

Protein attributes

Sequence length445 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

Hide | Top

General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Subunit structure

Homotetramer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the xylose isomerase family.

Hide | Top

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processD-xylose metabolic process

Inferred from electronic annotation. Source: HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 445445Xylose isomerase HAMAP MF_00455
PRO_0000236962

Sites

Active site991 By similarity
Active site1021 By similarity
Metal binding2301Magnesium 1 By similarity
Metal binding2661Magnesium 1 By similarity
Metal binding2661Magnesium 2 By similarity
Metal binding2691Magnesium 2 By similarity
Metal binding2941Magnesium 1 By similarity
Metal binding3051Magnesium 2 By similarity
Metal binding3071Magnesium 2 By similarity
Metal binding3371Magnesium 1 By similarity

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
Q5KYS6-1 [UniParc].

Last modified February 1, 2005. Version 1.
Checksum: 76C5030599092303

FASTA44550,382
        10         20         30         40         50         60 
MAYFPNIGTI PYEGPESRNP LAFKFYNPDE KVGGKTMEEH LRFSVAYWHT FTGDGSDPFG 

        70         80         90        100        110        120 
VGNMIRPWNT YSGMDLAKAR VEAAFELFEK LNVPFFCFHD VDIAPEGETL SETYKNLDEI 

       130        140        150        160        170        180 
VDMIEEYMKT SKTKLLWNTA NLFSHPRFVH GAATSCNADV FAYAAAKVKK GLEIAKRLGA 

       190        200        210        220        230        240 
ENYVFWGGRE GYETLLNTDM KLELDNLARF LHMAVDYAKE IGFDGQFLIE PKPKEPTKHQ 

       250        260        270        280        290        300 
YDFDVATALA FLQTYGLKDH FKFNIEANHA TLAGHTFEHE LRVARIHGML GSVDANQGDT 

       310        320        330        340        350        360 
LLGWDTDEFP TDLYTTTLAM YEILQNGGLG RGGLNFDAKV RRGSFEPEDL FYAHIAGMDS 

       370        380        390        400        410        420 
FAIGLKVAHR LLEDRVFEQF IEERYKSYTE GIGREIVEGT ADFKKLEEYA LQLGDIRNTS 

       430        440 
GRLERLKTLL NQYLLEVSAP SGSRS

« Hide

Hide | Top

References

[1]"Thermoadaptation trait revealed by the genome sequence of thermophilic Geobacillus kaustophilus."
Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H., Matsui S., Uchiyama I.
Nucleic Acids Res. 32:6292-6303(2004) [PubMed: 15576355] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HTA426.

Hide | Top

Cross-references

Sequence databases

BA000043 Genomic DNA. Translation: BAD76160.1.
RefSeqYP_147728.1.

3D structure databases

SMRQ5KYS6. Positions 3-435.
ModBaseSearch...

Genome annotation databases

GeneID3184312.
GenomeReviewsGene locus GK1875 in contig BA000043_GR.
KEGGgka:GK1875.
NMPDRfig|235909.3.peg.724.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ5KYS6.
OMAQFLIEPK.

Enzyme and pathway databases

BioCycGKAU235909:GK1875-MON.
BRENDA5.3.1.5. 281547.

Family and domain databases

HAMAPMF_00455.
[Tree]
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR012307. Xyl_isomerase_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
IPR018115. Xylose_isomerase_AS.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
TIGRFAMsTIGR02630. xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Hide | Top

Entry information

Entry nameXYLA_GEOKA
AccessionPrimary (citable) accession number: Q5KYS6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: February 1, 2005
Last modified: November 3, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Hide | Top

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents