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Protein

Urease subunit beta

Gene

ureB

Organism
Geobacillus kaustophilus (strain HTA426)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Urea + H2O = CO2 + 2 NH3.UniRule annotation

Pathwayi: urea degradation

This protein is involved in step 1 of the subpathway that synthesizes CO(2) and NH(3) from urea (urease route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Urease subunit alpha (ureC), Urease subunit beta (ureB), Urease subunit gamma (ureA)
This subpathway is part of the pathway urea degradation, which is itself part of Nitrogen metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CO(2) and NH(3) from urea (urease route), the pathway urea degradation and in Nitrogen metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciGKAU235909:GJO7-2019-MONOMER.
UniPathwayiUPA00258; UER00370.

Names & Taxonomyi

Protein namesi
Recommended name:
Urease subunit betaUniRule annotation (EC:3.5.1.5UniRule annotation)
Alternative name(s):
Urea amidohydrolase subunit betaUniRule annotation
Gene namesi
Name:ureBUniRule annotation
Ordered Locus Names:GK1931
OrganismiGeobacillus kaustophilus (strain HTA426)
Taxonomic identifieri235909 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus
Proteomesi
  • UP000001172 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 111111Urease subunit betaPRO_0000234249Add
BLAST

Interactioni

Subunit structurei

Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.UniRule annotation

Protein-protein interaction databases

STRINGi235909.GK1931.

Structurei

3D structure databases

ProteinModelPortaliQ5KYM0.
SMRiQ5KYM0. Positions 1-101.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the urease beta subunit family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105KI2. Bacteria.
COG0832. LUCA.
HOGENOMiHOG000077770.
KOiK01429.
OMAiNSFLEFD.
OrthoDBiPOG091H08S9.

Family and domain databases

CDDicd00407. Urease_beta. 1 hit.
Gene3Di2.10.150.10. 1 hit.
HAMAPiMF_01954. Urease_beta. 1 hit.
InterProiIPR002019. Urease_beta.
[Graphical view]
PfamiPF00699. Urease_beta. 1 hit.
[Graphical view]
SUPFAMiSSF51278. SSF51278. 1 hit.
TIGRFAMsiTIGR00192. urease_beta. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5KYM0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPGEYRLRE EPIVCNRQKS ATKLTVVNRG DRPVQVGSHF HFFEVNSFLE
60 70 80 90 100
FDRQAAYGKH LNIPAGTAVR FEPGDAKQVE LVPFSGERRV YGLNNMVNGP
110
LDGNGKGGVR E
Length:111
Mass (Da):12,386
Last modified:February 1, 2005 - v1
Checksum:i14482992CC6A79B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000043 Genomic DNA. Translation: BAD76216.1.
RefSeqiWP_011231417.1. NC_006510.1.

Genome annotation databases

EnsemblBacteriaiBAD76216; BAD76216; GK1931.
GeneIDi3183529.
KEGGigka:GK1931.
PATRICi21965233. VBIGeoKau81518_2072.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000043 Genomic DNA. Translation: BAD76216.1.
RefSeqiWP_011231417.1. NC_006510.1.

3D structure databases

ProteinModelPortaliQ5KYM0.
SMRiQ5KYM0. Positions 1-101.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi235909.GK1931.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD76216; BAD76216; GK1931.
GeneIDi3183529.
KEGGigka:GK1931.
PATRICi21965233. VBIGeoKau81518_2072.

Phylogenomic databases

eggNOGiENOG4105KI2. Bacteria.
COG0832. LUCA.
HOGENOMiHOG000077770.
KOiK01429.
OMAiNSFLEFD.
OrthoDBiPOG091H08S9.

Enzyme and pathway databases

UniPathwayiUPA00258; UER00370.
BioCyciGKAU235909:GJO7-2019-MONOMER.

Family and domain databases

CDDicd00407. Urease_beta. 1 hit.
Gene3Di2.10.150.10. 1 hit.
HAMAPiMF_01954. Urease_beta. 1 hit.
InterProiIPR002019. Urease_beta.
[Graphical view]
PfamiPF00699. Urease_beta. 1 hit.
[Graphical view]
SUPFAMiSSF51278. SSF51278. 1 hit.
TIGRFAMsiTIGR00192. urease_beta. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiURE2_GEOKA
AccessioniPrimary (citable) accession number: Q5KYM0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: February 1, 2005
Last modified: September 7, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.