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Protein

Adenine deaminase

Gene

ade

Organism
Geobacillus kaustophilus (strain HTA426)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Manganese

Enzyme and pathway databases

BioCyciGKAU235909:GJO7-2186-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:GK2098
OrganismiGeobacillus kaustophilus (strain HTA426)
Taxonomic identifieri235909 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus
Proteomesi
  • UP000001172 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 577577Adenine deaminasePRO_0000142424Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi235909.GK2098.

Structurei

3D structure databases

ProteinModelPortaliQ5KY53.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the adenine deaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.
OrthoDBiPOG091H00I8.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin. 1 hit.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5KY53-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHSTLHNQIA AAAKQTKADL VIQNGKIVNV FTREIIEGDL AIVEGMIVGI
60 70 80 90 100
GRYEGEKTID AEGRYICPGL IDGHVHIESS MVPPSEFARV VLPHGVTTVI
110 120 130 140 150
ADPHEIANVA GVCGIQFMLD EAKRTPLDVY MMLPSCVPAA SFERAGAVLS
160 170 180 190 200
AAELAPFFND ERVLGLAEVM DYPSLREQHP SMLDKLALAA NANRLIDGHL
210 220 230 240 250
AGLDADAVNV YRSARIHTDH ECVTPDEALE RVRRGMYVLI RQGSVAKDLK
260 270 280 290 300
KLLPAIHEHN ARRFLFCTDD KHLDDLWFEG SVDHNVRLAI QAGLDPLLAI
310 320 330 340 350
QMATLNAAEC YRLPTKGAVA PGYDADFLFV DDLETLNITH VFKAGRLVAQ
360 370 380 390 400
HGQTVFPAER SAESLEQPLL HSIRCQAVDE TDLRIPMKRG TKAHVIEIIP
410 420 430 440 450
NHLHTNHLIT DVDVQEGAFC PSIERDLLKL VVVERHRGLG IGLGIVRGFG
460 470 480 490 500
FKAGAIASSI AHDSHHIIAA GTNDRDLTAA IEQLRQQHGG LAVIKDGAVL
510 520 530 540 550
ASLPLEIGGL MTRKDYTEVL SGLKQIDKAL KAIGANGSFN PFITLSFLAL
560 570
PVIPELKLTD QGLFDVNKWE FIPVEAV
Length:577
Mass (Da):62,927
Last modified:February 1, 2005 - v1
Checksum:i43ED8125C26386FC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000043 Genomic DNA. Translation: BAD76383.1.
RefSeqiWP_011231583.1. NC_006510.1.

Genome annotation databases

EnsemblBacteriaiBAD76383; BAD76383; GK2098.
GeneIDi3184768.
KEGGigka:GK2098.
PATRICi21965591. VBIGeoKau81518_2251.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000043 Genomic DNA. Translation: BAD76383.1.
RefSeqiWP_011231583.1. NC_006510.1.

3D structure databases

ProteinModelPortaliQ5KY53.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi235909.GK2098.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD76383; BAD76383; GK2098.
GeneIDi3184768.
KEGGigka:GK2098.
PATRICi21965591. VBIGeoKau81518_2251.

Phylogenomic databases

eggNOGiENOG4105CPN. Bacteria.
COG1001. LUCA.
HOGENOMiHOG000276949.
KOiK01486.
OMAiCTDDKHL.
OrthoDBiPOG091H00I8.

Enzyme and pathway databases

BioCyciGKAU235909:GJO7-2186-MONOMER.

Family and domain databases

Gene3Di2.30.40.10. 2 hits.
HAMAPiMF_01518. Adenine_deamin. 1 hit.
InterProiIPR006679. Adenine_deam.
IPR026912. Adenine_deam_C.
IPR006680. Amidohydro-rel.
IPR011059. Metal-dep_hydrolase_composite.
IPR032466. Metal_Hydrolase.
[Graphical view]
PfamiPF13382. Adenine_deam_C. 1 hit.
PF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMiSSF51338. SSF51338. 2 hits.
SSF51556. SSF51556. 1 hit.
TIGRFAMsiTIGR01178. ade. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiADEC_GEOKA
AccessioniPrimary (citable) accession number: Q5KY53
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 12, 2005
Last sequence update: February 1, 2005
Last modified: September 7, 2016
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.