Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q5KY26 (GLSA_GEOKA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutaminase
EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:GK2125
OrganismGeobacillus kaustophilus (strain HTA426) [Complete proteome] [HAMAP]
Taxonomic identifier235909 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Geobacillus ›

Protein attributes

Sequence length308 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity.

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 308308Glutaminase HAMAP-Rule MF_00313
PRO_1000048336

Sites

Binding site651Substrate By similarity
Binding site1161Substrate By similarity
Binding site1611Substrate By similarity
Binding site1681Substrate By similarity
Binding site1921Substrate By similarity
Binding site2441Substrate By similarity
Binding site2621Substrate; via amide nitrogen By similarity

Secondary structure

1 .............................................. 308
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q5KY26 [UniParc].

Last modified February 1, 2005. Version 1.
Checksum: 9D8954EFFC212BB9

FASTA30833,773
        10         20         30         40         50         60 
MLVYNQEELV RFVEEAKQYA RYGKVADYIP ALGKANPNEL SIAIYTPDDE VVSAGDVTVK 

        70         80         90        100        110        120 
VTLQSISKII ALALVLIDRG EDEVFHKVGM EPTDYPFHSI AKLEEKPAKP LNPMINAGAL 

       130        140        150        160        170        180 
VVTSMIQGGS VSERLERLLA FVRRLAGNER ISYSDEVARS EFETAFLNRS LCYFLKQHRI 

       190        200        210        220        230        240 
IDEDVEELME LYTKQCAIEM TCIDLARIGL VLALDGRDPH SSEPLMPLDV ARICKTFMVT 

       250        260        270        280        290        300 
CGMYNSSGEF AIKVGIPAKS GVSGGILAAV PGRCGIGVFG PALDDKGNSL TGVKLLERLS 


KTYSLSIF

« Hide

References

[1]"Thermoadaptation trait revealed by the genome sequence of thermophilic Geobacillus kaustophilus."
Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H., Matsui S., Uchiyama I.
Nucleic Acids Res. 32:6292-6303(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HTA426.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000043 Genomic DNA. Translation: BAD76410.1.
RefSeqYP_147978.1. NC_006510.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2PBYX-ray2.07A/B/C/D1-308[»]
ProteinModelPortalQ5KY26.
SMRQ5KY26. Positions 2-308.
ModBaseSearch...

Protein-protein interaction databases

STRING235909.GK2125.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD76410; BAD76410; GK2125.
GeneID3186387.
KEGGgka:GK2125.
PATRIC21965645. VBIGeoKau81518_2278.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
OMADRGEDEV.
ProtClustDBPRK00971.

Enzyme and pathway databases

BioCycGKAU235909:GJO7-2213-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. PBP_transp_fold. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceQ5KY26.

Entry information

Entry nameGLSA_GEOKA
AccessionPrimary (citable) accession number: Q5KY26
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 1, 2005
Last modified: May 1, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents