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Protein

Anti-sigma F factor

Gene

spoIIAB

Organism
Geobacillus kaustophilus (strain HTA426)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.UniRule annotation

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
Biological processSporulation
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Anti-sigma F factorUniRule annotation (EC:2.7.11.1UniRule annotation)
Alternative name(s):
Stage II sporulation protein ABUniRule annotation
Gene namesi
Name:spoIIABUniRule annotation
Ordered Locus Names:GK2309
OrganismiGeobacillus kaustophilus (strain HTA426)
Taxonomic identifieri235909 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillusGeobacillus thermoleovorans group
Proteomesi
  • UP000001172 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002035651 – 146Anti-sigma F factorAdd BLAST146

Interactioni

Protein-protein interaction databases

STRINGi235909.GK2309

Structurei

3D structure databases

ProteinModelPortaliQ5KXJ2
SMRiQ5KXJ2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the anti-sigma-factor family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108ZBE Bacteria
COG2172 LUCA
HOGENOMiHOG000269931
KOiK06379
OMAiHAYEDKI
OrthoDBiPOG091H0LCB

Family and domain databases

CDDicd00075 HATPase_c, 1 hit
Gene3Di3.30.565.10, 1 hit
HAMAPiMF_00637 Anti_sigma_F, 1 hit
InterProiView protein in InterPro
IPR010194 Anti-sigma_F
IPR003594 HATPase_C
IPR036890 HATPase_C_sf
PANTHERiPTHR35526:SF2 PTHR35526:SF2, 1 hit
PfamiView protein in Pfam
PF13581 HATPase_c_2, 1 hit
SMARTiView protein in SMART
SM00387 HATPase_c, 1 hit
SUPFAMiSSF55874 SSF55874, 1 hit
TIGRFAMsiTIGR01925 spIIAB, 1 hit

Sequencei

Sequence statusi: Complete.

Q5KXJ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNEMHLQFS ARSENESFAR VTVAAFVAQL DPTMDELTEI KTVVSEAVTN
60 70 80 90 100
AIIHGYNNDP NGIVSISVII EDGVVHLTVR DEGVGIPDIE EARQPLFTTK
110 120 130 140
PELERSGMGF TIMENFMDEV IVESEVNKGT TVYLKKHIAK SKALCN
Length:146
Mass (Da):16,181
Last modified:February 1, 2005 - v1
Checksum:i7724FB497A29B20D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000043 Genomic DNA Translation: BAD76594.1
RefSeqiWP_011231791.1, NC_006510.1

Genome annotation databases

EnsemblBacteriaiBAD76594; BAD76594; GK2309
GeneIDi32064158
KEGGigka:GK2309

Similar proteinsi

Entry informationi

Entry nameiSP2AB_GEOKA
AccessioniPrimary (citable) accession number: Q5KXJ2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: February 1, 2005
Last modified: May 23, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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