Shikimate 5-dehydrogenase - Geobacillus kaustophilus (strain HTA426)

Contribute

Read comments (?) or add your own

Q5KWX7 (Q5KWX7_GEOKA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 58. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

text xml rdf/xml gff fasta

to top of page

Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

to top of page

Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Submitted name:
Shikimate 5-dehydrogenase EMBL BAD76809.1
EC=1.1.1.25 EMBL BAD76809.1

Gene names

Ordered Locus Names:

GK2524

Organism

Geobacillus kaustophilus (strain HTA426) [Complete proteome] [HAMAP]

Taxonomic identifier

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length	276 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	Shikimate + NADP⁺ = 3-dehydroshikimate + NADPH. SAAS SAAS011342
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. SAAS SAAS011342

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis SAAS SAAS011342
Ligand	NADP SAAS SAAS011342
Molecular function	Oxidoreductase RuleBase RU004037 SAAS SAAS011342 EMBL BAD76809.1
Technical term	3D-structure PDB 2EGG Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro shikimate 3-dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

Q5KWX7 [UniParc].

Last modified February 1, 2005. Version 1.
Checksum: 1054EC5195AD3B06
Show »

276

30,427

        10         20         30         40         50         60 
MEKVYGLIGF PVEHSLSPLM HNDAFARLGI PARYHLFSVE PGQVGAAIAG VRALGIAGVN 

        70         80         90        100        110        120 
VTIPHKLAVI PFLDEVDEHA RRIGAVNTII NNDGRLVGYN TDGLGYVQAL EEEMNITLDG 

       130        140        150        160        170        180 
KRILVIGAGG GARGIYFSLL STAAERIDMA NRTVEKAERL VREGDERRSA YFSLAEAETR 

       190        200        210        220        230        240 
LAEYDIIINT TSVGMHPRVE VQPLSLERLR PGVIVSDIIY NPLETKWLKE AKARGARVQN 

       250        260        270 
GVGMLVYQGA LAFEKWTGQW PDVNRMKQLV IEALRR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Thermoadaptation trait revealed by the genome sequence of thermophilic Geobacillus kaustophilus." Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H., Matsui S., Uchiyama I. Nucleic Acids Res. 32:6292-6303(2004) [PubMed: 15576355] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HTA426.
[2]	"Crystal Structure of Shikimate 5-Dehydrogenase (AroE) from Geobacillus kaustophilus." Bagautdinov B., Kunishima N. Submitted (FEB-2007) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.25 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

BA000043 Genomic DNA. Translation: BAD76809.1.

RefSeq

YP_148377.1. NC_006510.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2EGG	X-ray	2.25	A/B	1-276	[»]

ProteinModelPortal

SMR

Q5KWX7. Positions 1-276.

ModBase

Protocols and materials databases

StructuralBiologyKnowledgebase

Genome annotation databases

GeneID

GenomeReviews

Gene locus GK2524 in contig BA000043_GR.

KEGG

NMPDR

fig|235909.3.peg.2616.

PATRIC

21966509. VBIGeoKau81518_2703.

Organism-specific databases

CMR

Phylogenomic databases

HOGENOM

OMA

ProtClustDB

Family and domain databases

HAMAP

MF_00222. Shikimate_DH_AroE.
[Tree]

InterPro

IPR016040. NAD(P)-bd_dom.
IPR011342. Shikimate_DH.
IPR013708. Shikimate_DH-bd_N.
IPR022893. Shikimate_quinate_DH.
IPR006151. Shikm_DH/Glu-tRNA_Rdtase.
[Graphical view]

Gene3D

G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.

KO

Pfam

PF01488. Shikimate_DH. 1 hit.
PF08501. Shikimate_dh_N. 1 hit.
[Graphical view]

TIGRFAMs

TIGR00507. AroE. 1 hit.

ProtoNet

Entry information

Entry name

Q5KWX7_GEOKA

Accession

Primary (citable) accession number: Q5KWX7

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 2005
Last sequence update:	February 1, 2005
Last modified:	December 14, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

to top of page

Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info