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Q5KWX3 (PSD_GEOKA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:GK2528
OrganismGeobacillus kaustophilus (strain HTA426) [Complete proteome] [HAMAP]
Taxonomic identifier235909 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length264 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00662

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00662

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00662

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 1 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 225225Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000029659
Chain226 – 26439Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000029660

Sites

Site225 – 2262Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2261Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5KWX3 [UniParc].

Last modified February 1, 2005. Version 1.
Checksum: 5CAFA6E9F31CA62F

FASTA26430,042
        10         20         30         40         50         60 
MRKWLYRLFI ELTNHSLSSK LLASFAKSRL SGLLISSYAK IYHINQDEME KSLKNYKTLQ 

        70         80         90        100        110        120 
QLFVRRLKAG VRPVDADEHT VVSPVDAVIE DMGTIRENCE MIVKGKPYSI AEMLGSVEAA 

       130        140        150        160        170        180 
QPYVNGFFFI LYLSPSHYHR IHSPISGVIE KQWALGRKSY PVNRLGLKYG RRPLEKNYRL 

       190        200        210        220        230        240 
ITEVTAGGKR LAIVKIGAMF VNSIELTHEG EQLVKGEEMA YFSFGSTVVL LFERGSFAPD 

       250        260 
PRIVAPMPIK VGERLGYWCE AHER

« Hide

References

[1]"Thermoadaptation trait revealed by the genome sequence of thermophilic Geobacillus kaustophilus."
Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H., Matsui S., Uchiyama I.
Nucleic Acids Res. 32:6292-6303(2004) [PubMed: 15576355] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HTA426.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000043 Genomic DNA. Translation: BAD76813.1.
RefSeqYP_148381.1. NC_006510.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3186051.
GenomeReviewsGene locus GK2528 in contig BA000043_GR.
KEGGgka:GK2528.
NMPDRfig|235909.3.peg.2620.
PATRIC21966517. VBIGeoKau81518_2707.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG302256.
OMANKREWSI.
ProtClustDBPRK03140.

Enzyme and pathway databases

BioCycGKAU235909:GK2528-MONOMER.

Family and domain databases

HAMAPMF_00662. PS_decarb_type1.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
KOK01613.
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_GEOKA
AccessionPrimary (citable) accession number: Q5KWX3
Entry history
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: February 1, 2005
Last modified: January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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