Q5KW49 (RS4_GEOKA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S4

Gene names

Name:	rpsD
Ordered Locus Names:	GK2802

Organism

Geobacillus kaustophilus (strain HTA426) [Complete proteome] [HAMAP]

Taxonomic identifier

235909 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Geobacillus › Geobacillus kaustophilus

Protein attributes

Sequence length	200 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit By similarity. HAMAP-Rule MF_01306 With S5 and S12 plays an important role in translational accuracy By similarity. HAMAP-Rule MF_01306
Subunit structure	Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity By similarity.
Sequence similarities	Belongs to the ribosomal protein S4P family. Contains 1 S4 RNA-binding domain.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	small ribosomal subunit Inferred from electronic annotation. Source: InterPro
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 200	200	30S ribosomal protein S4 HAMAP-Rule MF_01306		PRO_0000132387
Regions
	Domain	92 – 152	61	S4 RNA-binding

Sequences

	Sequence		Length	Mass (Da)
	Q5KW49 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: 850033D61B6013F0	FASTA	200	23,209
	10 20 30 40 50 60 MARYTGPMWK ISRRLGISLS GTGKELQKRP YPPGQHGPGQ RRKLSEYGLQ LQEKQKLRHM 70 80 90 100 110 120 YGVNERQFRK TFEEAGKMPG KHGENFMILL ESRLDNLVYR LGLARTRRQA RQLVTHGHIL 130 140 150 160 170 180 VDGSRVNIPS YRVKPGQTIA VREKSRNLQV IKEALEANNY IPDYLTFNPE KMEGTYTRLP 190 200 ERSELPAEIN EALIVEFYSR

References

[1]

"Thermoadaptation trait revealed by the genome sequence of thermophilic Geobacillus kaustophilus." Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H., Matsui S., Uchiyama I. Nucleic Acids Res. 32:6292-6303(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HTA426.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000043 Genomic DNA. Translation: BAD77087.1.
RefSeq	YP_148655.1. NC_006510.1.
3D structure databases
ProteinModelPortal	Q5KW49.
SMR	Q5KW49. Positions 43-200.
ModBase	Search...
Protein-protein interaction databases
STRING	235909.GK2802.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAD77087; BAD77087; GK2802.
GeneID	3186773.
KEGG	gka:GK2802.
PATRIC	21967079. VBIGeoKau81518_2988.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0522.
HOGENOM	HOG000221004.
KO	K02986.
OMA	THGHILV.
ProtClustDB	PRK05327.
Enzyme and pathway databases
BioCyc	GKAU235909:GJO7-2897-MONOMER.
Family and domain databases
Gene3D	1.10.1050.10. 1 hit. 3.10.290.10. 1 hit.
HAMAP	MF_01306_B. Ribosomal_S4_B.
InterPro	IPR022801. Ribosomal_S4/S9. IPR001912. Ribosomal_S4/S9_N. IPR005709. Ribosomal_S4_bac-type. IPR018079. Ribosomal_S4_CS. IPR002942. S4_RNA-bd. [Graphical view]
PANTHER	PTHR11831. PTHR11831. 1 hit.
Pfam	PF00163. Ribosomal_S4. 1 hit. PF01479. S4. 1 hit. [Graphical view]
SMART	SM00363. S4. 1 hit. [Graphical view]
TIGRFAMs	TIGR01017. rpsD_bact. 1 hit.
PROSITE	PS00632. RIBOSOMAL_S4. 1 hit. PS50889. S4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RS4_GEOKA

Accession

Primary (citable) accession number: Q5KW49

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 15, 2005
Last sequence update:	February 1, 2005
Last modified:	May 1, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program