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Q5KVP7 (FENR_GEOKA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase
Short name=FNR
Short name=Fd-NADP+ reductase
EC=1.18.1.2
Gene names
Ordered Locus Names:GK2954
OrganismGeobacillus kaustophilus (strain HTA426) [Complete proteome] [HAMAP]
Taxonomic identifier235909 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length332 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP MF_01685

Subunit structure

Homodimer By similarity. HAMAP MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: EC

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 332332Ferredoxin--NADP reductase HAMAP MF_01685
PRO_0000364840

Sites

Binding site201FAD By similarity
Binding site391FAD By similarity
Binding site471FAD By similarity
Binding site521FAD By similarity
Binding site921FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1261FAD; via amide nitrogen By similarity
Binding site2881FAD By similarity
Binding site3291FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5KVP7 [UniParc].

Last modified February 1, 2005. Version 1.
Checksum: 67869E30390FEB58

FASTA33236,670
        10         20         30         40         50         60 
MSVKEDRNVY DVTIIGGGPT GMFAAFYGGL RQMKVKIIES LPQLGGQLAA LYPEKYIYDV 

        70         80         90        100        110        120 
AGFPKVRAQE LVNQLKEQMD LFSPTVCLNE SVDTLEKQED GTFKLVTNQQ IHYSKTVIIT 

       130        140        150        160        170        180 
AGNGAFQPRR LEIESASRYE GKNLHYFIND LGQFSGKRVL VCGGGDSAVD WSLMLEPIAQ 

       190        200        210        220        230        240 
SVTIVHRRDK FRAHEHSVEQ LKKSSVQVKT PFVPVELVGD EHAIRQVILE HVKEGTKETI 

       250        260        270        280        290        300 
DVDAVIVNYG FISSLGPIKN WGLDIEKNAI KVNSRMETNI PGVYAAGDIC TYDGKIKLIA 

       310        320        330 
CGFGEAPIAI SSAKTYIDPT ARMQPAHSTS LF

« Hide

References

[1]"Thermoadaptation trait revealed by the genome sequence of thermophilic Geobacillus kaustophilus."
Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H., Matsui S., Uchiyama I.
Nucleic Acids Res. 32:6292-6303(2004) [PubMed: 15576355] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HTA426.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000043 Genomic DNA. Translation: BAD77239.1.
RefSeqYP_148807.1. NC_006510.1.

3D structure databases

ProteinModelPortalQ5KVP7.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3184400.
GenomeReviewsGene locus GK2954 in contig BA000043_GR.
KEGGgka:GK2954.
NMPDRfig|235909.3.peg.2966.
PATRIC21967439. VBIGeoKau81518_3151.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG669726.
OMAFQVFELG.
ProtClustDBCLSK2459135.

Enzyme and pathway databases

BioCycGKAU235909:GK2954-MONOMER.

Family and domain databases

HAMAPMF_01685. FENR2.
[Tree]
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
KOK00384.
PANTHERPTHR22912:SF53. PTHR22912:SF53. 1 hit.
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR_GEOKA
AccessionPrimary (citable) accession number: Q5KVP7
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: February 1, 2005
Last modified: January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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