Q5KVG9 (Q5KVG9_GEOKA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrodipicolinate synthase EMBL BAD77317.1
EC=4.2.1.52 EMBL BAD77317.1

Gene names

Ordered Locus Names:

GK3032

Organism

Geobacillus kaustophilus (strain HTA426) [Complete proteome] [HAMAP]

Taxonomic identifier

235909 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length	313 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-aspartate 4-semialdehyde + pyruvate = dihydrodipicolinate + 2 H2O. SAAS SAAS005263
Pathway	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4. SAAS SAAS005263
Subunit structure	Homotetramer By similarity. SAAS SAAS005263
Subcellular location	Cytoplasm By similarity SAAS SAAS005263.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Diaminopimelate biosynthesis SAAS SAAS005263 Lysine biosynthesis SAAS SAAS005263
Cellular component	Cytoplasm SAAS SAAS005263
Ligand	Schiff base SAAS SAAS005263
Molecular function	Lyase SAAS SAAS005263 EMBL BAD77317.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	diaminopimelate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	dihydrodipicolinate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5KVG9 [UniParc]. Last modified February 1, 2005. Version 1. Checksum: C3C127606644B0C3	FASTA	313	34,434
	10 20 30 40 50 60 MAYHEAKERL RGSIAPVVTP FDEEGNVDFA ALAALIDWHI ESGTHGISVT GTSGEPSSLT 70 80 90 100 110 120 LEERKQVMET AKKAVAGRVP FVPGTGSTNH AETIELTKFA QEIGADAAMV IVPYYNRPSQ 130 140 150 160 170 180 QALYKHFKAV AEAVDIPIIV YNIPGRTAVN LEVKTLARLA EDCPNIIGVK ESNKDFEHVN 190 200 210 220 230 240 RVLWHCGRDF LLFSGIELLC YPMLAIGGAG SISATANVVP HKVAELHDAW FEGDIKRAQD 250 260 270 280 290 300 LHFELMELND VLFIETNPGP VKAALGMMGK ITPKLRLPLD LPSEEHQQQI RRTLVKYGLL 310 AEETQDEEMQ KAT

References

[1]

"Thermoadaptation trait revealed by the genome sequence of thermophilic Geobacillus kaustophilus." Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H., Matsui S., Uchiyama I. Nucleic Acids Res. 32:6292-6303(2004) [PubMed: 15576355] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HTA426.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000043 Genomic DNA. Translation: BAD77317.1.
RefSeq	YP_148885.1. NC_006510.1.
3D structure databases
ProteinModelPortal	Q5KVG9.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3184175.
GenomeReviews	Gene locus GK3032 in contig BA000043_GR.
KEGG	gka:GK3032.
NMPDR	fig|235909.3.peg.3103.
PATRIC	21967609. VBIGeoKau81518_3236.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG358848.
OMA	GSTNHAE.
ProtClustDB	CLSK904759.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR002220. Dihydrodipicolinate_synth-like. IPR020625. Dihydrodipicolinate_synth_AS. IPR005263. Dihydrodipicolinate_synth_DapA. IPR012691. HpaI_NOT_DapA. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01714.
PANTHER	PTHR12128. DHDPS. 1 hit.
Pfam	PF00701. DHDPS. 1 hit. [Graphical view]
PIRSF	PIRSF001365. DHDPS. 1 hit.
PRINTS	PR00146. DHPICSNTHASE.
TIGRFAMs	TIGR00674. DapA. 1 hit. TIGR02313. HpaI-NOT-DapA. 1 hit.
PROSITE	PS00666. DHDPS_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5KVG9_GEOKA

Accession

Primary (citable) accession number: Q5KVG9

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 2005
Last sequence update:	February 1, 2005
Last modified:	December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)