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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Geobacillus kaustophilus (strain HTA426)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:GK3401
OrganismiGeobacillus kaustophilus (strain HTA426)
Taxonomic identifieri235909 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillusGeobacillus thermoleovorans group
Proteomesi
  • UP000001172 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002420251 – 557Arginine--tRNA ligaseAdd BLAST557

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi235909.GK3401

Structurei

3D structure databases

ProteinModelPortaliQ5KUF0
SMRiQ5KUF0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi132 – 142"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiHGMSTRQ
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q5KUF0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIVGQIKEK MKEEIRQAAV RAGLASADEL PDVLLEVPRD KAHGDYSTNI
60 70 80 90 100
AMQLARIAKK PPRAIAEAIV GQLDRERMSV ARIEIAGPGF INFYMDNRYL
110 120 130 140 150
TAVVPAILQA GQAYGESNVG NGEKVQVEFV SANPTGDLHL GHARGAAVGD
160 170 180 190 200
SLCNILAKAG FDVTREYYIN DAGKQIYNLA KSVEARYFQA LGVDMPLPED
210 220 230 240 250
GYYGDDIVEI GKKLAEEYGD RFVEMEEEER LAFFRDYGLR YELEKIKKDL
260 270 280 290 300
ADFRVPFDVW YSETSLYESG KIDEALSTLR ERGYIYEQDG ATWFRSTAFG
310 320 330 340 350
DDKDRVLIKQ DGTYTYLLPD IAYHQDKLRR GFKKLINIWG ADHHGYIPRM
360 370 380 390 400
KAAIAALGYD PEALEVEIIQ MVNLYQNGER VKMSKRTGKA VTMRELMEEV
410 420 430 440 450
GVDAVRYFFA MRSGDTHLDF DMDLAVSQSN ENPVYYVQYA HARVSSILRQ
460 470 480 490 500
AEEQHISYDG DLALHHLVET EKEIELLKVL GDFPDVVAEA ALKRMPHRVT
510 520 530 540 550
AYAFDLASAL HSFYNAEKVL DLDNIEKTKA RLALVKAVQI TLQNALALIG

VSAPEQM
Length:557
Mass (Da):62,698
Last modified:February 1, 2005 - v1
Checksum:iBBECD71C87879653
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000043 Genomic DNA Translation: BAD77686.1
RefSeqiWP_011232868.1, NC_006510.1

Genome annotation databases

EnsemblBacteriaiBAD77686; BAD77686; GK3401
GeneIDi32065285
KEGGigka:GK3401

Similar proteinsi

Entry informationi

Entry nameiSYR_GEOKA
AccessioniPrimary (citable) accession number: Q5KUF0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: February 1, 2005
Last modified: March 28, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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