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Protein
Submitted name:

Histone deacetylase clr3, putative

Gene

CNC00780

Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Histone deacetylase clr3, putativeImported
Gene namesi
Ordered Locus Names:CNC00780Imported
OrganismiCryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)Imported
Taxonomic identifieri214684 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesTremellaceaeFilobasidiellaFilobasidiella/Cryptococcus neoformans species complex
ProteomesiUP000002149 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiFungiDB:CNC00780.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi214684.CNC00780.

Structurei

3D structure databases

ProteinModelPortaliQ5KL48.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000161343.
InParanoidiQ5KL48.
KOiK11407.
OMAiCYDDRMK.
OrthoDBiEOG75B8GB.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
3.40.800.20. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR019154. Arb2_domain.
IPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR017321. Hist_deAcase_II_yeast.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF09757. Arb2. 1 hit.
PF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037919. HDAC_II_yeast. 1 hit.
PRINTSiPR01270. HDASUPER.

Sequencei

Sequence statusi: Complete.

Q5KL48-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHSPSPLCAP PSLRPAPAHR RMAHTAAMHT GPPPAAPTNV GNSPSHTTMA
60 70 80 90 100
MPGAAARIAR TGYIYDPLMM LHCMEGYMPT AENVMDNGDG HPEDPMRIKR
110 120 130 140 150
IFTRLAEQGL IRRMKRLDFE EVKFEQVLLV HGEEMWDKVQ ATELLSDQQI
160 170 180 190 200
QDMKEYYDQL SLYVCRETAH CARLSAGGVI QACRSVCKNE VRNAFAIVRP
210 220 230 240 250
PGHHAEPNEH MGFCFFNNVA VATREMQREG LAKKVLILDW DVHHGNGTQR
260 270 280 290 300
AFWHDGDVLY MSLHRHEGGT FYPNSDFGSL NMVGDGEGVG KSVNIPWPGP
310 320 330 340 350
GFGDADYIYA FQRIIMPIAY EFDPDLVIIS AGFDAADGDM LGQCRVTPAA
360 370 380 390 400
YGHMTHMLSS LAGGKLVVAL EGGYNLRAIS DSALAVARVL LGEIPPELGI
410 420 430 440 450
MRASEAATEV VYQVALEQSK YWKCIDVKAC EPPEVTELEN GTSPVYTIPD
460 470 480 490 500
LLKIHRAHHM FTKHQLYQIP LASQELEAAF GGQIICNENM YEVGEKGVLV
510 520 530 540 550
VFVHDFGNLR VETDGARSTN IHLANSYLLD TSDAVVSWVK TKGYNIIDVN
560 570 580 590 600
ILKQLPTEYP EGPKMVVKQA NDMESKLMKY IWDNYIELSE CEKVVFIGHG
610 620 630 640 650
TGCQAIMDLV NARDVELKVK AVVQVAGLHS LVRPNPSNKE KLSWFKQCNQ
660 670 680 690 700
IYVPAEHVVL EDEKVKRRLG DAVFTSQKAK VVDVLNDVLP RIKAFVESKV
710 720 730
EDGLAPRAHS GLDGLYGLGG AGAGGELVVV NGHVHVG
Length:737
Mass (Da):81,312
Last modified:February 15, 2005 - v1
Checksum:i0FD26D8AFD503856
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017343 Genomic DNA. Translation: AAW42071.1.
RefSeqiXP_569378.1. XM_569378.1.
UniGeneiFne.6105.

Genome annotation databases

EnsemblFungiiAAW42071; AAW42071; CNC00780.
GeneIDi3256392.
KEGGicne:CNC00780.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017343 Genomic DNA. Translation: AAW42071.1.
RefSeqiXP_569378.1. XM_569378.1.
UniGeneiFne.6105.

3D structure databases

ProteinModelPortaliQ5KL48.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi214684.CNC00780.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiAAW42071; AAW42071; CNC00780.
GeneIDi3256392.
KEGGicne:CNC00780.

Organism-specific databases

EuPathDBiFungiDB:CNC00780.

Phylogenomic databases

HOGENOMiHOG000161343.
InParanoidiQ5KL48.
KOiK11407.
OMAiCYDDRMK.
OrthoDBiEOG75B8GB.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
3.40.800.20. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR019154. Arb2_domain.
IPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR017321. Hist_deAcase_II_yeast.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF09757. Arb2. 1 hit.
PF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037919. HDAC_II_yeast. 1 hit.
PRINTSiPR01270. HDASUPER.
ProtoNetiSearch...

Publicationsi

  1. "The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans."
    Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D., Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E., Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A., Fox D.S.
    , Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C., Janbon G., Jones S.J., Koo H.L., Krzywinski M.I., Kwon-Chung J.K., Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A., Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E., Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A., Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W., Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.
    Science 307:1321-1324(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JEC21 / ATCC MYA-565Imported.

Entry informationi

Entry nameiQ5KL48_CRYNJ
AccessioniPrimary (citable) accession number: Q5KL48
Secondary accession number(s): Q55V32
Entry historyi
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: May 27, 2015
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.