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Protein
Submitted name:

Histone deacetylase clr3, putative

Gene

CNC00780

Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Histone deacetylase clr3, putativeImported
Gene namesi
Ordered Locus Names:CNC00780Imported
OrganismiCryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)Imported
Taxonomic identifieri214684 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesTremellaceaeFilobasidiellaFilobasidiella/Cryptococcus neoformans species complex
Proteomesi
  • UP000002149 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiFungiDB:CNC00780.

PTM / Processingi

Proteomic databases

PaxDbiQ5KL48.

Interactioni

Protein-protein interaction databases

STRINGi214684.XP_569378.1.

Structurei

3D structure databases

ProteinModelPortaliQ5KL48.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini66 – 369304Hist_deacetylInterPro annotationAdd
BLAST
Domaini383 – 563181Arb2InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1343. Eukaryota.
COG0123. LUCA.
HOGENOMiHOG000161343.
InParanoidiQ5KL48.
KOiK11407.
OMAiCYDDRMK.
OrthoDBiEOG75B8GB.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
3.40.800.20. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR019154. Arb2_domain.
IPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR017321. Hist_deAcase_II_yeast.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF09757. Arb2. 1 hit.
PF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037919. HDAC_II_yeast. 1 hit.
PRINTSiPR01270. HDASUPER.

Sequencei

Sequence statusi: Complete.

Q5KL48-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAHTAAMHTG PPPAAPTNVG NSPSHTTMAM PGAAARIART GYIYDPLMML
60 70 80 90 100
HCMEGYMPTA ENVMDNGDGH PEDPMRIKRI FTRLAEQGLI RRMKRLDFEE
110 120 130 140 150
VKFEQVLLVH GEEMWDKVQA TELLSDQQIQ DMKEYYDQLS LYVCRETAHC
160 170 180 190 200
ARLSAGGVIQ ACRSVCKNEV RNAFAIVRPP GHHAEPNEHM GFCFFNNVAV
210 220 230 240 250
ATREMQREGL AKKVLILDWD VHHGNGTQRA FWHDGDVLYM SLHRHEGGTF
260 270 280 290 300
YPNSDFGSLN MVGDGEGVGK SVNIPWPGPG FGDADYIYAF QRIIMPIAYE
310 320 330 340 350
FDPDLVIISA GFDAADGDML GQCRVTPAAY GHMTHMLSSL AGGKLVVALE
360 370 380 390 400
GGYNLRAISD SALAVARVLL GEIPPELGIM RASEAATEVV YQVALEQSKY
410 420 430 440 450
WKCIDVKACE PPEVTELENG TSPVYTIPDL LKIHRAHHMF TKHQLYQIPL
460 470 480 490 500
ASQELEAAFG GQIICNENMY EVGEKGVLVV FVHDFGNLRV ETDGARSTNI
510 520 530 540 550
HLANSYLLDT SDAVVSWVKT KGYNIIDVNI LKQLPTEYPE GPKMVVKQAN
560 570 580 590 600
DMESKLMKYI WDNYIELSEC EKVVFIGHGT GCQAIMDLVN ARDVELKVKA
610 620 630 640 650
VVQVAGLHSL VRPNPSNKEK LSWFKQCNQI YVPAEHVVLE DEKVKRRLGD
660 670 680 690 700
AVFTSQKAKV VDVLNDVLPR IKAFVESKVE DGLAPRAHSG LDGLYGLGGA
710
GAGGELVVVN GHVHVG
Length:716
Mass (Da):79,051
Last modified:February 17, 2016 - v2
Checksum:i1663CDC09D4C30D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017343 Genomic DNA. Translation: AAW42071.2.
RefSeqiXP_569378.1. XM_569378.1.
UniGeneiFne.6105.

Genome annotation databases

EnsemblFungiiAAW42071; AAW42071; CNC00780.
GeneIDi3256392.
KEGGicne:CNC00780.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017343 Genomic DNA. Translation: AAW42071.2.
RefSeqiXP_569378.1. XM_569378.1.
UniGeneiFne.6105.

3D structure databases

ProteinModelPortaliQ5KL48.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi214684.XP_569378.1.

Proteomic databases

PaxDbiQ5KL48.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiAAW42071; AAW42071; CNC00780.
GeneIDi3256392.
KEGGicne:CNC00780.

Organism-specific databases

EuPathDBiFungiDB:CNC00780.

Phylogenomic databases

eggNOGiKOG1343. Eukaryota.
COG0123. LUCA.
HOGENOMiHOG000161343.
InParanoidiQ5KL48.
KOiK11407.
OMAiCYDDRMK.
OrthoDBiEOG75B8GB.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
3.40.800.20. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR019154. Arb2_domain.
IPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR017321. Hist_deAcase_II_yeast.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF09757. Arb2. 1 hit.
PF00850. Hist_deacetyl. 1 hit.
[Graphical view]
PIRSFiPIRSF037919. HDAC_II_yeast. 1 hit.
PRINTSiPR01270. HDASUPER.
ProtoNetiSearch...

Publicationsi

  1. "The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans."
    Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D., Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E., Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A., Fox D.S.
    , Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C., Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J., Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A., Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E., Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A., Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W., Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.
    Science 307:1321-1324(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JEC21 / ATCC MYA-565Imported.

Entry informationi

Entry nameiQ5KL48_CRYNJ
AccessioniPrimary (citable) accession number: Q5KL48
Secondary accession number(s): Q55V32
Entry historyi
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 17, 2016
Last modified: March 16, 2016
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.