Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q5KIM3 (Q5KIM3_CRYNJ) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length479 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2 By similarity. RuleBase RU361137

Catalytic activity

Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine. RuleBase RU361137

Cofactor

Binds 1 lipoyl cofactor covalently By similarity. RuleBase RU361137

Binds 2 lipoyl cofactors covalently By similarity. RuleBase RU361137

Binds 3 lipoyl cofactors covalently By similarity. RuleBase RU361137

Subcellular location

Mitochondrion matrix By similarity RuleBase RU361137.

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU361137

Contains 1 lipoyl-binding domain. RuleBase RU361137

Sequences

Sequence LengthMass (Da)Tools
Q5KIM3 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 89D4D6870C6568AF

FASTA47950,790
        10         20         30         40         50         60 
MLSFAQVAKR SAAVSFRRQA VASRTLRTSA PSNVLSKFAM PAMSPTMTEG GVAQWKKKEG 

        70         80         90        100        110        120 
ESFSAGDVLI EIETDKATID VEAQDDGIMA KIIAQDGTKN IAVGTPIAII GEEGDDLSQA 

       130        140        150        160        170        180 
DALAAESQSE SAPSQKEAAP KEEKTAPKEE KSESSTTPAV GVPGEQKSGA GDAQTSPAKA 

       190        200        210        220        230        240 
PEHPSKGDRP KFFASPLARK IALENGIPLA EIKGTGPNGR IVEADVKNYK PSAAAASTPA 

       250        260        270        280        290        300 
AGKSAAVPAD YEDIPTSNMR RTIGKRLTES KQQLPHYYVT VEVNMDRVLK LREVFNKAGE 

       310        320        330        340        350        360 
SKTKLSVNDF IVKAASLALA DVPEANSAWL GETIRTYKKA DICVAVATPN GLITPIIKDV 

       370        380        390        400        410        420 
GAKGLATISA ETKALASRAR DGKLKPEEYQ GGSFTISNLG MFGVDEFTAI INPPQSCILA 

       430        440        450        460        470 
VGKTTTKLEL APEDPKGFKA VQVMKVTLSA DHRTVDGAVG ARWLKAFREY MEQPLTFML 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE017344 Genomic DNA. Translation: AAW43137.1.
RefSeqXP_570444.1. XM_570444.1.
UniGeneFne.6690.

3D structure databases

ProteinModelPortalQ5KIM3.
SMRQ5KIM3. Positions 249-479.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING214684.CND02450.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiAAW43137; AAW43137; CND02450.
GeneID3257075.
KEGGcne:CND02450.

Phylogenomic databases

HOGENOMHOG000281566.
KOK00627.
OrthoDBEOG7TTQJ2.

Family and domain databases

Gene3D3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR006257. LAT1.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
TIGRFAMsTIGR01349. PDHac_trf_mito. 1 hit.
PROSITEPS50968. BIOTINYL_LIPOYL. 1 hit.
PS00189. LIPOYL. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ5KIM3_CRYNJ
AccessionPrimary (citable) accession number: Q5KIM3
Secondary accession number(s): Q55TR2
Entry history
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: July 9, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)