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Q5KGI6

- Q5KGI6_CRYNJ

UniProt

Q5KGI6 - Q5KGI6_CRYNJ

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Protein
Submitted name: Alpha-amylase, putative
Gene
CNE03480
Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi141 – 1411Calcium 1 By similarityUniRule annotation
Metal bindingi182 – 1821Calcium 1; via carbonyl oxygen By similarityUniRule annotation
Metal bindingi195 – 1951Calcium 1 By similarityUniRule annotation
Active sitei226 – 2261Nucleophile By similarityUniRule annotation
Metal bindingi226 – 2261Calcium 2 By similarityUniRule annotation
Metal bindingi230 – 2301Calcium 1; via carbonyl oxygen By similarityUniRule annotation
Active sitei250 – 2501Proton donor By similarityUniRule annotation
Metal bindingi250 – 2501Calcium 2 By similarityUniRule annotation
Sitei318 – 3181Transition state stabilizer By similarityUniRule annotation

GO - Molecular functioni

  1. alpha-amylase activity Source: UniProtKB-EC
  2. calcium ion binding Source: InterPro

GO - Biological processi

  1. carbohydrate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Keywords - Ligandi

CalciumUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-amylase, putativeImported (EC:3.2.1.1Imported)
Gene namesi
Ordered Locus Names:CNE03480Imported
OrganismiCryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)Imported
Taxonomic identifieri214684 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesTremellaceaeFilobasidiellaFilobasidiella/Cryptococcus neoformans species complex
ProteomesiUP000002149: Chromosome 5

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi50 ↔ 58 By similarityUniRule annotation
Disulfide bondi170 ↔ 184 By similarityUniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi214684.CNE03480.

Structurei

3D structure databases

ProteinModelPortaliQ5KGI6.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000165530.
KOiK01176.
OrthoDBiEOG7RBZJ4.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR013777. A-amylase_fun.
IPR015340. A_amylase_DUF1966_C.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF09260. DUF1966. 1 hit.
[Graphical view]
PIRSFiPIRSF001024. Alph-amyl_fung. 1 hit.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5KGI6-1 [UniParc]FASTAAdd to Basket

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MLTYQAALAL IPFISFLPAY ALDADAMRSR SVYQVVTDRF ARNSSSTGDC    50
NVADRTYCGG TWSALADKLD YIQGMGFDTV WISPVVENIG GTTGEGEAYH 100
GYWTLDPESL NSNFGSADDL KTLSSSLHAR GMYLQVDVVV NHVAATSSST 150
FQPSESYGPF STSEDYHPFC WITDYNNQTN VEQCWLGDDS VALADLNTES 200
DTVVSYWNQW ITDLVSNYTF DAIRIDTVKH VRQSFWPDFV NAAGVFNQGE 250
VLLADVPYVA GYQKNASINP FNYPVYYPLV RAFNGTGQSF SELINMVSYV 300
NSNFTDPTLL GTFLDNHDNA RFESFVTDPS LIKNAQAYPL VTDGIPYVYY 350
GSEAGFNGGN DPENREPMWT SNYDTSSDMY KFFTSLNAAR SAAGNASSTF 400
YTDKMTLSQP SESTLLVAKK PLMSVFSNSG SSASNTSVSV DSSSSGWAAS 450
TNVIDALTCE SFTTDDSGNL AVTIYQGEPR VLIEDSQKGS LCGGSSSNSS 500
STSNDSGAGM TTKVSGWVAL AGVFVAGLQV LL 532
Length:532
Mass (Da):57,639
Last modified:February 15, 2005 - v1
Checksum:i05971682AD484190
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017345 Genomic DNA. Translation: AAW43607.1.
RefSeqiXP_570914.1. XM_570914.1.
UniGeneiFne.7153.

Genome annotation databases

EnsemblFungiiAAW43607; AAW43607; CNE03480.
GeneIDi3257780.
KEGGicne:CNE03480.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE017345 Genomic DNA. Translation: AAW43607.1 .
RefSeqi XP_570914.1. XM_570914.1.
UniGenei Fne.7153.

3D structure databases

ProteinModelPortali Q5KGI6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 214684.CNE03480.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii AAW43607 ; AAW43607 ; CNE03480 .
GeneIDi 3257780.
KEGGi cne:CNE03480.

Phylogenomic databases

HOGENOMi HOG000165530.
KOi K01176.
OrthoDBi EOG7RBZJ4.

Family and domain databases

Gene3Di 2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProi IPR013777. A-amylase_fun.
IPR015340. A_amylase_DUF1966_C.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
PANTHERi PTHR10357. PTHR10357. 1 hit.
Pfami PF00128. Alpha-amylase. 1 hit.
PF09260. DUF1966. 1 hit.
[Graphical view ]
PIRSFi PIRSF001024. Alph-amyl_fung. 1 hit.
SMARTi SM00642. Aamy. 1 hit.
[Graphical view ]
SUPFAMi SSF51445. SSF51445. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans."
    Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D., Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E., Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A., Fox D.S.
    , Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C., Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J., Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A., Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E., Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A., Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W., Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.
    Science 307:1321-1324(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JEC21 / ATCC MYA-565.

Entry informationi

Entry nameiQ5KGI6_CRYNJ
AccessioniPrimary (citable) accession number: Q5KGI6
Secondary accession number(s): Q55S33
Entry historyi
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: July 9, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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