Q5KDQ7 (Q5KDQ7_CRYNJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Elongation factor Tu RuleBase RU004061

Gene names

Ordered Locus Names:

CNG03130

Organism

Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) [Reference proteome] EMBL AAW44713.1

Taxonomic identifier

214684 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Basidiomycota › Agaricomycotina › Tremellomycetes › Tremellales › Tremellaceae › Filobasidiella › Filobasidiella/Cryptococcus neoformans species complex › Cryptococcus neoformans › Cryptococcus neoformans var. neoformans

Protein attributes

Sequence length	464 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. RuleBase RU000325
Sequence similarities	Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily. RuleBase RU000325

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	GTP-binding RuleBase RU000323 Nucleotide-binding
Molecular function	Elongation factor RuleBase RU000325 EMBL AAW44713.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW GTPase activity Inferred from electronic annotation. Source: InterPro translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5KDQ7 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 498AA1F7AB036528	FASTA	464	50,930
	10 20 30 40 50 60 MLRNALQSRL SSTLRTAELR AARPVAGPSV LAARTFVSKP LPSPRFRAAV LTPRRLPTRS 70 80 90 100 110 120 YAAEAGGKFT RSKPHFNIGT IGHVDHGKTT LTAAITKHLA EQGGGKFMDY SQIDKAPEEK 130 140 150 160 170 180 ARGITISTAH VEYETPNRHY AHIDCPGHAD YIKNMITGAA QLDGAIIVVS ATDGQMPQTR 190 200 210 220 230 240 EHLLLARQVG IKKLVVFINK VDQVDDPEML ELVEMEMREL LGQYGFDGEE TPIVMGSALA 250 260 270 280 290 300 ALEGRDPERG AQKIQELMEK ADEWLDVPSR DLDKPFLMYV EDVFSISGRG TVVTGKVERG 310 320 330 340 350 360 TITKGSEVEI VGLGAPVKTI LTGIEMFHKE LERGEAGDNM GALLRGIKRE QVRRGQVLVQ 370 380 390 400 410 420 PGSIKSVKKF KAQIYILTKE EGGRYTPFMA NYRPQLFIRT TDVTCALTFP EGTEGAHEKL 430 440 450 460 VMPGDNVEMI GDLVHDIALE PGSRFTLREG GKTIGTGIVS EIYE

References

[1]

"The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans." Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D., Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E., Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A., Fox D.S. , Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C., Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J., Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A., Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E., Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A., Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W., Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W. Science 307:1321-1324(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JEC21 / ATCC MYA-565.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017347 Genomic DNA. Translation: AAW44713.1.
RefSeq	XP_572020.1. XM_572020.1.
UniGene	Fne.7634.
3D structure databases
ProteinModelPortal	Q5KDQ7.
SMR	Q5KDQ7. Positions 73-461.
ModBase	Search...
Protein-protein interaction databases
STRING	214684.CNG03130.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3258600.
KEGG	cne:CNG03130.
Phylogenomic databases
HOGENOM	HOG000229290.
KO	K02358.
OrthoDB	EOG42RHGS.
Family and domain databases
HAMAP	MF_00118_B. EF_Tu_B.
InterPro	IPR000795. EF_GTP-bd_dom. IPR027417. P-loop_NTPase. IPR005225. Small_GTP-bd_dom. IPR009001. Transl_elong_EF1A/Init_IF2_C. IPR004161. Transl_elong_EFTu/EF1A_2. IPR004541. Transl_elong_EFTu/EF1A_bac/org. IPR004160. Transl_elong_EFTu/EF1A_C. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
PANTHER	PTHR23115:SF31. PTHR23115:SF31. 1 hit.
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. PF03143. GTP_EFTU_D3. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SUPFAM	SSF50465. Elong_init_C. 1 hit. SSF52540. SSF52540. 1 hit. SSF50447. Translat_factor. 1 hit.
TIGRFAMs	TIGR00485. EF-Tu. 1 hit. TIGR00231. small_GTP. 1 hit.
PROSITE	PS00301. EFACTOR_GTP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5KDQ7_CRYNJ

Accession

Primary (citable) accession number: Q5KDQ7
Secondary accession number(s): Q55PQ1

Entry history

Integrated into UniProtKB/TrEMBL:	February 15, 2005
Last sequence update:	February 15, 2005
Last modified:	May 29, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)