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Protein

Elongation factor Tu

Gene

CNG03130

Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionElongation factorUniRule annotationImported
Biological processProtein biosynthesis
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Gene namesi
Ordered Locus Names:CNG03130Imported
OrganismiCryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)Imported
Taxonomic identifieri214684 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesCryptococcaceaeCryptococcusCryptococcus neoformans species complex
Proteomesi
  • UP000002149 Componenti: Chromosome 7

Organism-specific databases

EuPathDBiFungiDB:CNG03130

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiQ5KDQ7

Interactioni

Protein-protein interaction databases

STRINGi214684.XP_572020.1

Structurei

3D structure databases

ProteinModelPortaliQ5KDQ7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini73 – 269Tr-type GInterPro annotationAdd BLAST197

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0460 Eukaryota
COG0050 LUCA
HOGENOMiHOG000229290
InParanoidiQ5KDQ7
KOiK02358
OMAiYGHIDCP
OrthoDBiEOG092C2HV8

Family and domain databases

CDDicd03697 EFTU_II, 1 hit
HAMAPiMF_00118_B EF_Tu_B, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR033720 EFTU_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004541 Transl_elong_EFTu/EF1A_bac/org
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00485 EF-Tu, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5KDQ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRNALQSRL SSTLRTAELR AARPVAGPSV LAARTFVSKP LPSPRFRAAV
60 70 80 90 100
LTPRRLPTRS YAAEAGGKFT RSKPHFNIGT IGHVDHGKTT LTAAITKHLA
110 120 130 140 150
EQGGGKFMDY SQIDKAPEEK ARGITISTAH VEYETPNRHY AHIDCPGHAD
160 170 180 190 200
YIKNMITGAA QLDGAIIVVS ATDGQMPQTR EHLLLARQVG IKKLVVFINK
210 220 230 240 250
VDQVDDPEML ELVEMEMREL LGQYGFDGEE TPIVMGSALA ALEGRDPERG
260 270 280 290 300
AQKIQELMEK ADEWLDVPSR DLDKPFLMYV EDVFSISGRG TVVTGKVERG
310 320 330 340 350
TITKGSEVEI VGLGAPVKTI LTGIEMFHKE LERGEAGDNM GALLRGIKRE
360 370 380 390 400
QVRRGQVLVQ PGSIKSVKKF KAQIYILTKE EGGRYTPFMA NYRPQLFIRT
410 420 430 440 450
TDVTCALTFP EGTEGAHEKL VMPGDNVEMI GDLVHDIALE PGSRFTLREG
460
GKTIGTGIVS EIYE
Length:464
Mass (Da):50,930
Last modified:February 15, 2005 - v1
Checksum:i498AA1F7AB036528
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017347 Genomic DNA Translation: AAW44713.1
RefSeqiXP_572020.1, XM_572020.1
UniGeneiFne.7634

Genome annotation databases

EnsemblFungiiAAW44713; AAW44713; CNG03130
GeneIDi3258600
KEGGicne:CNG03130

Similar proteinsi

Entry informationi

Entry nameiQ5KDQ7_CRYNJ
AccessioniPrimary (citable) accession number: Q5KDQ7
Secondary accession number(s): Q55PQ1
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: May 23, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health