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Protein

DNA ligase

Gene

CNI04170

Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n)-3'-hydroxyl + 5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) + AMP + diphosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigaseUniRule annotationImported
Biological processDNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:CNI04170Imported
OrganismiCryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)Imported
Taxonomic identifieri214684 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesCryptococcaceaeCryptococcusCryptococcus neoformans species complex
Proteomesi
  • UP000002149 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiFungiDB:CNI04170

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiQ5KB11

Interactioni

Protein-protein interaction databases

STRINGi214684.XP_572602.1

Structurei

3D structure databases

ProteinModelPortaliQ5KB11
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini535 – 672DNA_LIGASE_A3InterPro annotationAdd BLAST138

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0967 Eukaryota
COG1793 LUCA
InParanoidiQ5KB11
KOiK10747
OMAiWIKYKRD
OrthoDBiEOG092C0FHN

Family and domain databases

Gene3Di1.10.3260.10, 1 hit
HAMAPiMF_00407 DNA_ligase, 1 hit
InterProiView protein in InterPro
IPR022865 DNA_ligae_ATP-dep_bac/arc
IPR000977 DNA_ligase_ATP-dep
IPR012309 DNA_ligase_ATP-dep_C
IPR012310 DNA_ligase_ATP-dep_cent
IPR016059 DNA_ligase_ATP-dep_CS
IPR012308 DNA_ligase_ATP-dep_N
IPR036599 DNA_ligase_N_sf
IPR012340 NA-bd_OB-fold
PfamiView protein in Pfam
PF04679 DNA_ligase_A_C, 1 hit
PF01068 DNA_ligase_A_M, 1 hit
PF04675 DNA_ligase_A_N, 1 hit
SUPFAMiSSF117018 SSF117018, 1 hit
SSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00574 dnl1, 1 hit
PROSITEiView protein in PROSITE
PS00697 DNA_LIGASE_A1, 1 hit
PS00333 DNA_LIGASE_A2, 1 hit
PS50160 DNA_LIGASE_A3, 1 hit

Sequencei

Sequence statusi: Complete.

Q5KB11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDIEYPVKS NIRKKRTVIL SDDEDEGLGP SVIKEQVSSP KHSHLSDEET
60 70 80 90 100
EPPRKVAKTS SKVAPIFAPK EKKEKPSPKT SSALSKAPAK KIEVKSKGEK
110 120 130 140 150
PLASIFTKAT RKPEPKDDDE MSDEVKQKGK DEEEEDEIYD EVEDKQEGEA
160 170 180 190 200
AVKLASIFTK NQKSVPVADK GWKDGEAVPY PALVSTFEKI EATTKRLEIL
210 220 230 240 250
EFLTQFLLVV AKRDTATDAK GSMLLKVVYL CINRLCPDYM GIELGIGESL
260 270 280 290 300
LIKAIAESTG RAMPKIKEDL KKEGDLGKVA MNSRNTQSTM FKPKPLTVPY
310 320 330 340 350
VFQCLTDIAK ASGNASQAKK VGIIKKLLAA CQGTEAKFII RSLEGKLRIG
360 370 380 390 400
LADKTVVVAL AHAIVLKTIG DKKPPPEKLA IMLEQGAETV KAVYSELPSY
410 420 430 440 450
DLVIPALLQG GVEGLRERCK LTPGVPLKPM LAKPTKAITE VLDRFEGKEF
460 470 480 490 500
TCEYKYDGER AQVHLLEDGT ISVFSRNSEN MSAKYPDLVD QIPRSMKPTA
510 520 530 540 550
KTFVIDAEAV AYDLETKKIL PFQDLSRRKR KDVKAEDITV RVHIFAFDLL
560 570 580 590 600
YLNGESLLAK ELKERRQLLQ EHFQPVESEF AFAKSSDGST TEEIQALLEE
610 620 630 640 650
SVKDGCEGLM VKMLTSESST YEPSRRSMNW LKLKKDYLSG VGDSLDLVVV
660 670 680 690 700
GAYHGKGKRT AVYGAFLLAC YDPDSEHYQT ICKIGTGFSE EILTQFYELL
710 720 730 740 750
KPLELEVVRG DIEVGGAKPD VWFEPRVVWE VLTADLSLSP IYAAAHGVID
760 770 780 790 800
SRGISLRFPR FIRIRDDKSA DEATTAEQVS EFYQRQISAG GKKGAGADVD

DFW
Length:803
Mass (Da):89,050
Last modified:February 15, 2005 - v1
Checksum:i8F400926CE1B836A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017349 Genomic DNA Translation: AAW45295.1
RefSeqiXP_572602.1, XM_572602.1
UniGeneiFne.3837

Genome annotation databases

EnsemblFungiiAAW45295; AAW45295; CNI04170
GeneIDi3259559
KEGGicne:CNI04170

Similar proteinsi

Entry informationi

Entry nameiQ5KB11_CRYNJ
AccessioniPrimary (citable) accession number: Q5KB11
Secondary accession number(s): Q55MN6
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: May 23, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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