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Q5KB11

- Q5KB11_CRYNJ

UniProt

Q5KB11 - Q5KB11_CRYNJ

Protein

DNA ligase

Gene

CNI04170

Organism
Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (15 Feb 2005)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:CNI04170Imported
    OrganismiCryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans)Imported
    Taxonomic identifieri214684 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesTremellaceaeFilobasidiellaFilobasidiella/Cryptococcus neoformans species complex
    ProteomesiUP000002149: Chromosome 9

    Interactioni

    Protein-protein interaction databases

    STRINGi214684.CNI04170.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5KB11.
    SMRiQ5KB11. Positions 164-787.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    KOiK10747.
    OrthoDBiEOG7TXKRG.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    HAMAPiMF_00407. DNA_ligase.
    InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5KB11-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDIEYPVKS NIRKKRTVIL SDDEDEGLGP SVIKEQVSSP KHSHLSDEET    50
    EPPRKVAKTS SKVAPIFAPK EKKEKPSPKT SSALSKAPAK KIEVKSKGEK 100
    PLASIFTKAT RKPEPKDDDE MSDEVKQKGK DEEEEDEIYD EVEDKQEGEA 150
    AVKLASIFTK NQKSVPVADK GWKDGEAVPY PALVSTFEKI EATTKRLEIL 200
    EFLTQFLLVV AKRDTATDAK GSMLLKVVYL CINRLCPDYM GIELGIGESL 250
    LIKAIAESTG RAMPKIKEDL KKEGDLGKVA MNSRNTQSTM FKPKPLTVPY 300
    VFQCLTDIAK ASGNASQAKK VGIIKKLLAA CQGTEAKFII RSLEGKLRIG 350
    LADKTVVVAL AHAIVLKTIG DKKPPPEKLA IMLEQGAETV KAVYSELPSY 400
    DLVIPALLQG GVEGLRERCK LTPGVPLKPM LAKPTKAITE VLDRFEGKEF 450
    TCEYKYDGER AQVHLLEDGT ISVFSRNSEN MSAKYPDLVD QIPRSMKPTA 500
    KTFVIDAEAV AYDLETKKIL PFQDLSRRKR KDVKAEDITV RVHIFAFDLL 550
    YLNGESLLAK ELKERRQLLQ EHFQPVESEF AFAKSSDGST TEEIQALLEE 600
    SVKDGCEGLM VKMLTSESST YEPSRRSMNW LKLKKDYLSG VGDSLDLVVV 650
    GAYHGKGKRT AVYGAFLLAC YDPDSEHYQT ICKIGTGFSE EILTQFYELL 700
    KPLELEVVRG DIEVGGAKPD VWFEPRVVWE VLTADLSLSP IYAAAHGVID 750
    SRGISLRFPR FIRIRDDKSA DEATTAEQVS EFYQRQISAG GKKGAGADVD 800
    DFW 803
    Length:803
    Mass (Da):89,050
    Last modified:February 15, 2005 - v1
    Checksum:i8F400926CE1B836A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017349 Genomic DNA. Translation: AAW45295.1.
    RefSeqiXP_572602.1. XM_572602.1.
    UniGeneiFne.3837.

    Genome annotation databases

    EnsemblFungiiAAW45295; AAW45295; CNI04170.
    GeneIDi3259559.
    KEGGicne:CNI04170.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE017349 Genomic DNA. Translation: AAW45295.1 .
    RefSeqi XP_572602.1. XM_572602.1.
    UniGenei Fne.3837.

    3D structure databases

    ProteinModelPortali Q5KB11.
    SMRi Q5KB11. Positions 164-787.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 214684.CNI04170.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii AAW45295 ; AAW45295 ; CNI04170 .
    GeneIDi 3259559.
    KEGGi cne:CNI04170.

    Phylogenomic databases

    KOi K10747.
    OrthoDBi EOG7TXKRG.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    HAMAPi MF_00407. DNA_ligase.
    InterProi IPR022865. DNA_ligae_ATP-dep_bac/arc.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans."
      Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D., Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E., Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A., Fox D.S.
      , Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C., Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J., Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A., Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E., Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A., Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W., Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.
      Science 307:1321-1324(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JEC21 / ATCC MYA-565Imported.

    Entry informationi

    Entry nameiQ5KB11_CRYNJ
    AccessioniPrimary (citable) accession number: Q5KB11
    Secondary accession number(s): Q55MN6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 15, 2005
    Last sequence update: February 15, 2005
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3