Q5KB11 (Q5KB11_CRYNJ) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617

Gene names

Ordered Locus Names:

CNI04170

Organism

Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) [Reference proteome] EMBL AAW45295.1

Taxonomic identifier

214684 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Basidiomycota › Agaricomycotina › Tremellomycetes › Tremellales › Tremellaceae › Filobasidiella › Filobasidiella/Cryptococcus neoformans species complex › Cryptococcus neoformans › Cryptococcus neoformans var. neoformans

Protein attributes

Sequence length	803 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617 EMBL AAW45295.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5KB11 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 8F400926CE1B836A	FASTA	803	89,050
	10 20 30 40 50 60 MSDIEYPVKS NIRKKRTVIL SDDEDEGLGP SVIKEQVSSP KHSHLSDEET EPPRKVAKTS 70 80 90 100 110 120 SKVAPIFAPK EKKEKPSPKT SSALSKAPAK KIEVKSKGEK PLASIFTKAT RKPEPKDDDE 130 140 150 160 170 180 MSDEVKQKGK DEEEEDEIYD EVEDKQEGEA AVKLASIFTK NQKSVPVADK GWKDGEAVPY 190 200 210 220 230 240 PALVSTFEKI EATTKRLEIL EFLTQFLLVV AKRDTATDAK GSMLLKVVYL CINRLCPDYM 250 260 270 280 290 300 GIELGIGESL LIKAIAESTG RAMPKIKEDL KKEGDLGKVA MNSRNTQSTM FKPKPLTVPY 310 320 330 340 350 360 VFQCLTDIAK ASGNASQAKK VGIIKKLLAA CQGTEAKFII RSLEGKLRIG LADKTVVVAL 370 380 390 400 410 420 AHAIVLKTIG DKKPPPEKLA IMLEQGAETV KAVYSELPSY DLVIPALLQG GVEGLRERCK 430 440 450 460 470 480 LTPGVPLKPM LAKPTKAITE VLDRFEGKEF TCEYKYDGER AQVHLLEDGT ISVFSRNSEN 490 500 510 520 530 540 MSAKYPDLVD QIPRSMKPTA KTFVIDAEAV AYDLETKKIL PFQDLSRRKR KDVKAEDITV 550 560 570 580 590 600 RVHIFAFDLL YLNGESLLAK ELKERRQLLQ EHFQPVESEF AFAKSSDGST TEEIQALLEE 610 620 630 640 650 660 SVKDGCEGLM VKMLTSESST YEPSRRSMNW LKLKKDYLSG VGDSLDLVVV GAYHGKGKRT 670 680 690 700 710 720 AVYGAFLLAC YDPDSEHYQT ICKIGTGFSE EILTQFYELL KPLELEVVRG DIEVGGAKPD 730 740 750 760 770 780 VWFEPRVVWE VLTADLSLSP IYAAAHGVID SRGISLRFPR FIRIRDDKSA DEATTAEQVS 790 800 EFYQRQISAG GKKGAGADVD DFW

References

[1]

"The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans." Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D., Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E., Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A., Fox D.S. , Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C., Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J., Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A., Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E., Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A., Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W., Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W. Science 307:1321-1324(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JEC21 / ATCC MYA-565.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE017349 Genomic DNA. Translation: AAW45295.1.
RefSeq	XP_572602.1. XM_572602.1.
UniGene	Fne.3837.
3D structure databases
ProteinModelPortal	Q5KB11.
SMR	Q5KB11. Positions 164-787.
ModBase	Search...
Protein-protein interaction databases
STRING	214684.CNI04170.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3259559.
KEGG	cne:CNI04170.
Phylogenomic databases
KO	K10747.
OrthoDB	EOG4RV60K.
Family and domain databases
Gene3D	1.10.3260.10. 1 hit. 2.40.50.140. 1 hit.
HAMAP	MF_00407. DNA_ligase.
InterPro	IPR022865. DNA_ligae_ATP-dep_bac/arc. IPR000977. DNA_ligase_ATP-dep. IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit. SSF117018. SSF117018. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS00697. DNA_LIGASE_A1. 1 hit. PS00333. DNA_LIGASE_A2. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5KB11_CRYNJ

Accession

Primary (citable) accession number: Q5KB11
Secondary accession number(s): Q55MN6

Entry history

Integrated into UniProtKB/TrEMBL:	February 15, 2005
Last sequence update:	February 15, 2005
Last modified:	May 1, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)