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Protein

Aspartate aminotransferase

Gene

mAAT

Organism
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate aminotransferaseUniRule annotation (EC:2.6.1.1UniRule annotation)
Gene namesi
Name:mAATImported
ORF Names:AAEL002399Imported
OrganismiAedes aegypti (Yellowfever mosquito) (Culex aegypti)Imported
Taxonomic identifieri7159 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraNematoceraCulicoideaCulicidaeCulicinaeAediniAedesStegomyia
Proteomesi
  • UP000008820 Componenti: Unassembled WGS sequence

PTM / Processingi

Proteomic databases

PRIDEiQ5K6H3.

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi7159.AAEL002399-PA.

Structurei

3D structure databases

ProteinModelPortaliQ5K6H3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini57 – 424Aminotran_1_2InterPro annotationAdd BLAST368

Phylogenomic databases

eggNOGiKOG1411. Eukaryota.
COG1448. LUCA.
HOGENOMiHOG000185898.
KOiK14455.
OMAiWANHAAV.
OrthoDBiEOG091G06G3.
PhylomeDBiQ5K6H3.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11879. PTHR11879. 1 hit.
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSiPR00799. TRANSAMINASE.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5K6H3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MACSKTFQGT AVLLRNSAVF NGCISKRASS WWGAVQMGPP DVILGVTEAY
60 70 80 90 100
KKDTNPKKIN LGVGAYRDDN GKPFVLPSVR KAEQRMMEKQ LDKEYSPISG
110 120 130 140 150
TAEFCKHSIT LALGDDSQHV ANGQNATVQA ISGTGALRVG GAFLNGFFPG
160 170 180 190 200
TKDIYLPTPS WGNHGPIFRH SGLNVKAYRY YDPSTCGFDF KGALEDLSKI
210 220 230 240 250
PERSIVLLHA CAHNPTGVDP RPEQWAEMSA VFKKRNLFPF FDMAYQGFAS
260 270 280 290 300
GDVAKDALAV RAFLKDGHQI ALAQSFAKNM GLYGERAGAF SLICSDKEEA
310 320 330 340 350
ARTMSQIKIL IRPMYSNPPI HGARLVSEIL GDANLKQEWL GDVKLMADRI
360 370 380 390 400
ISVRTKLQDN LKKLGSSRNW QHITEQIGMF CFTGMDQKQC ERLTKEFSVY
410 420
LTKDGRISMA GVTTKNVDYL AEAIHAVTK
Length:429
Mass (Da):47,262
Last modified:February 15, 2005 - v1
Checksum:iC4E6F4F8984B476A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF395206 mRNA. Translation: AAQ02892.1.
CH477240 Genomic DNA. Translation: EAT46448.1.
RefSeqiXP_001655159.1. XM_001655109.1.
UniGeneiAae.18361.

Genome annotation databases

EnsemblMetazoaiAAEL002399-RA; AAEL002399-PA; AAEL002399.
GeneIDi5574496.
KEGGiaag:AaeL_AAEL002399.
VectorBaseiAAEL002399-RA; AAEL002399-PA; AAEL002399.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF395206 mRNA. Translation: AAQ02892.1.
CH477240 Genomic DNA. Translation: EAT46448.1.
RefSeqiXP_001655159.1. XM_001655109.1.
UniGeneiAae.18361.

3D structure databases

ProteinModelPortaliQ5K6H3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7159.AAEL002399-PA.

Proteomic databases

PRIDEiQ5K6H3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiAAEL002399-RA; AAEL002399-PA; AAEL002399.
GeneIDi5574496.
KEGGiaag:AaeL_AAEL002399.
VectorBaseiAAEL002399-RA; AAEL002399-PA; AAEL002399.

Phylogenomic databases

eggNOGiKOG1411. Eukaryota.
COG1448. LUCA.
HOGENOMiHOG000185898.
KOiK14455.
OMAiWANHAAV.
OrthoDBiEOG091G06G3.
PhylomeDBiQ5K6H3.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR000796. Asp_trans.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11879. PTHR11879. 1 hit.
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSiPR00799. TRANSAMINASE.
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5K6H3_AEDAE
AccessioniPrimary (citable) accession number: Q5K6H3
Entry historyi
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: November 30, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Miscellaneous

In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.UniRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.