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Protein

Non-structural protein 3

Gene
N/A
Organism
Rotavirus B (isolate RVB/Human/China/ADRV/1982) (RV-B) (Rotavirus B (isolate adult diarrhea rotavirus))
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May play a role in stimulating the translation of viral mRNAs.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-binding
Biological processTranslation regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Non-structural protein 3UniRule annotation
Short name:
NSP3UniRule annotation
Alternative name(s):
NCVP4UniRule annotation
Non-structural RNA-binding protein 34UniRule annotation
Short name:
NS34UniRule annotation
OrganismiRotavirus B (isolate RVB/Human/China/ADRV/1982) (RV-B) (Rotavirus B (isolate adult diarrhea rotavirus))
Taxonomic identifieri10942 [NCBI]
Taxonomic lineageiVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

  • Host cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Host cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003698481 – 347Non-structural protein 3Add BLAST347

Proteomic databases

PRIDEiQ5K037

Structurei

3D structure databases

ProteinModelPortaliQ5K037
SMRiQ5K037
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili230 – 257UniRule annotationAdd BLAST28

Sequence similaritiesi

Belongs to the rotavirus NSP3 family.UniRule annotation

Keywords - Domaini

Coiled coil

Family and domain databases

HAMAPiMF_04090 ROTA_NSP3, 1 hit
InterProiView protein in InterPro
IPR002873 Rotavirus_NSP3

Sequencei

Sequence statusi: Complete.

Q5K037-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALDALASIL ETVLRNCGIN EISRVTTKFE EALDDCGMKV DDWREAYYKE
60 70 80 90 100
RFPKRMTATT MASQIMNFEI ENLQLRNKAW AEGADRKFRL LSSFEIGNKD
110 120 130 140 150
GHTILVPKTR NAEILLANST SDLKLSSFPS EAVAKLAEEN EKMRKQIEHL
160 170 180 190 200
REQQTSKSTA TLCEALENMT ERMKLIEREK ETVRRMFLEC DKTNQRLRKQ
210 220 230 240 250
IQICEEEATD RLVLVNSHHR EEILIMKREI YRLQMENVTL KEQIDSIEQE
260 270 280 290 300
LDHSNRIVRG LANRAGLVVD EVDSGNETSD LSDDSDHDDH ENSESDLEDM
310 320 330 340
MDPGEDERIP RGGENPRRQA RMLQMREEME RLHEDMEILN LNLDLDI
Length:347
Mass (Da):40,357
Last modified:February 15, 2005 - v1
Checksum:iF99CB0E39BB51A98
GO

Sequence cautioni

The sequence AAA47329 differs from that shown. Reason: Frameshift at position 316.

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti168N → S in AAA47329 (PubMed:16054865).1
Sequence conflicti248E → G in AAA47329 (PubMed:16054865).1
Sequence conflicti281L → H in AAA47329 (PubMed:16054865).1
Sequence conflicti292N → S in AAA47329 (PubMed:16054865).1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M91436 mRNA Translation: AAA47329.1 Frameshift.
AJ867610 Genomic RNA Translation: CAI30288.1

Similar proteinsi

Entry informationi

Entry nameiNSP3_ROTGA
AccessioniPrimary (citable) accession number: Q5K037
Secondary accession number(s): Q86196
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 15, 2005
Last modified: May 23, 2018
This is version 29 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

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