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Protein

Non-structural protein 3

Gene
N/A
Organism
Rotavirus B (isolate Human/China/ADRV/1982) (RV-B) (Rotavirus B (isolate adult diarrhea rotavirus))
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Non-structural protein 3
Short name:
NSP3
OrganismiRotavirus B (isolate Human/China/ADRV/1982) (RV-B) (Rotavirus B (isolate adult diarrhea rotavirus))
Taxonomic identifieri10942 [NCBI]
Taxonomic lineageiVirusesdsRNA virusesReoviridaeSedoreovirinaeRotavirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 347347Non-structural protein 3PRO_0000369848Add
BLAST

Proteomic databases

PRIDEiQ5K037.

Structurei

3D structure databases

ProteinModelPortaliQ5K037.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili130 – 263134Sequence AnalysisAdd
BLAST
Coiled coili317 – 34630Sequence AnalysisAdd
BLAST

Sequence similaritiesi

Belongs to the rotavirus B NSP3 family.Curated

Keywords - Domaini

Coiled coil

Sequencei

Sequence statusi: Complete.

Q5K037-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALDALASIL ETVLRNCGIN EISRVTTKFE EALDDCGMKV DDWREAYYKE
60 70 80 90 100
RFPKRMTATT MASQIMNFEI ENLQLRNKAW AEGADRKFRL LSSFEIGNKD
110 120 130 140 150
GHTILVPKTR NAEILLANST SDLKLSSFPS EAVAKLAEEN EKMRKQIEHL
160 170 180 190 200
REQQTSKSTA TLCEALENMT ERMKLIEREK ETVRRMFLEC DKTNQRLRKQ
210 220 230 240 250
IQICEEEATD RLVLVNSHHR EEILIMKREI YRLQMENVTL KEQIDSIEQE
260 270 280 290 300
LDHSNRIVRG LANRAGLVVD EVDSGNETSD LSDDSDHDDH ENSESDLEDM
310 320 330 340
MDPGEDERIP RGGENPRRQA RMLQMREEME RLHEDMEILN LNLDLDI
Length:347
Mass (Da):40,357
Last modified:February 15, 2005 - v1
Checksum:iF99CB0E39BB51A98
GO

Sequence cautioni

The sequence AAA47329.1 differs from that shown. Reason: Frameshift at position 316. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti168 – 1681N → S in AAA47329 (PubMed:16054865).Curated
Sequence conflicti248 – 2481E → G in AAA47329 (PubMed:16054865).Curated
Sequence conflicti281 – 2811L → H in AAA47329 (PubMed:16054865).Curated
Sequence conflicti292 – 2921N → S in AAA47329 (PubMed:16054865).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M91436 mRNA. Translation: AAA47329.1. Frameshift.
AJ867610 Genomic RNA. Translation: CAI30288.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M91436 mRNA. Translation: AAA47329.1. Frameshift.
AJ867610 Genomic RNA. Translation: CAI30288.1.

3D structure databases

ProteinModelPortaliQ5K037.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ5K037.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Primary identification of the seventh RNA segment of the group B rotavirus ADRV."
    Mackow E.R., Chen G., Werner R., Fay M.E., Tao H.
    Submitted (AUG-1992) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "The evolution of human group B rotaviruses: correction and an update."
    Jiang B., Wang Y., Glass R.I., Fang Z.-Y.
    J. Clin. Virol. 34:158-159(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiNSP3_ROTGA
AccessioniPrimary (citable) accession number: Q5K037
Secondary accession number(s): Q86196
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 15, 2005
Last modified: October 1, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.