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Protein

Carboxypeptidase

Gene

CTSA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

CarboxypeptidaseUniRule annotation, Hydrolase, Protease

Protein family/group databases

ESTHERihuman-CTSA. Carboxypeptidase_S10.

Names & Taxonomyi

Protein namesi
Recommended name:
CarboxypeptidaseUniRule annotation (EC:3.4.16.-UniRule annotation)
Gene namesi
Name:CTSAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:9251. CTSA.

PTM / Processingi

Proteomic databases

EPDiQ5JZH0.
PaxDbiQ5JZH0.
PRIDEiQ5JZH0.

Expressioni

Gene expression databases

BgeeiQ5JZH0.
ExpressionAtlasiQ5JZH0. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000361562.

Chemistry

BindingDBiQ5JZH0.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S10 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1282. Eukaryota.
COG2939. LUCA.
GeneTreeiENSGT00790000123075.
HOGENOMiHOG000198295.
HOVERGENiHBG053652.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR018202. Ser_caboxypep_ser_AS.
[Graphical view]
PANTHERiPTHR11802. PTHR11802. 1 hit.
PfamiPF00450. Peptidase_S10. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q5JZH0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QDFFRLFPEY KNNKLFLTGE SYAGIYIPTL AVLVMQDPSM NLQGLAVGNG
60 70 80 90 100
LSSYEQNDNS LVYFAYYHGL LGNRLWSSLQ THCCSQNKCN FYDNKDLECV
110 120 130 140 150
TNLQEVARIV GNSGLNIYNL YAPCAGGVPS HFRTLLWSRI WATSSLACHS
160 170 180 190 200
SGCGIRHCCA QGIKCAWTPP APTQQLLPPT STTRTCGRPS TSRSSCHNGT

CA
Length:202
Mass (Da):22,248
Last modified:November 13, 2013 - v2
Checksum:i142F94C81E555F5C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei202 – 2021Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL008726 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000419493; ENSP00000408533; ENSG00000064601.
UCSCiuc061xkk.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL008726 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000361562.

Chemistry

BindingDBiQ5JZH0.

Protein family/group databases

ESTHERihuman-CTSA. Carboxypeptidase_S10.

Proteomic databases

EPDiQ5JZH0.
PaxDbiQ5JZH0.
PRIDEiQ5JZH0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000419493; ENSP00000408533; ENSG00000064601.
UCSCiuc061xkk.1. human.

Organism-specific databases

HGNCiHGNC:9251. CTSA.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1282. Eukaryota.
COG2939. LUCA.
GeneTreeiENSGT00790000123075.
HOGENOMiHOG000198295.
HOVERGENiHBG053652.

Miscellaneous databases

ChiTaRSiCTSA. human.

Gene expression databases

BgeeiQ5JZH0.
ExpressionAtlasiQ5JZH0. baseline and differential.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR018202. Ser_caboxypep_ser_AS.
[Graphical view]
PANTHERiPTHR11802. PTHR11802. 1 hit.
PfamiPF00450. Peptidase_S10. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
PROSITEiPS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and comparative analysis of human chromosome 20."
    Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
    , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
    Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (SEP-2013) to UniProtKB
    Cited for: IDENTIFICATION.
  4. "N-terminome analysis of the human mitochondrial proteome."
    Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M., Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.
    Proteomics 15:2519-2524(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiQ5JZH0_HUMAN
AccessioniPrimary (citable) accession number: Q5JZH0
Entry historyi
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: November 13, 2013
Last modified: May 11, 2016
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.