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Protein
Submitted name:

Four and a half LIM domains protein 1

Gene

FHL1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Four and a half LIM domains protein 1Imported
Gene namesi
Name:FHL1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000022267.16.
HGNCiHGNC:3702. FHL1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000022267.

Expressioni

Gene expression databases

BgeeiENSG00000022267.
ExpressionAtlasiQ5JXI3. baseline and differential.

Structurei

3D structure databases

SMRiQ5JXI3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini38 – 98LIM zinc-bindingInterPro annotationAdd BLAST61
Domaini99 – 160LIM zinc-bindingInterPro annotationAdd BLAST62
Domaini161 – 207LIM zinc-bindingInterPro annotationAdd BLAST47

Keywords - Domaini

LIM domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410INGD. Eukaryota.
ENOG410YDMU. LUCA.
GeneTreeiENSGT00760000118910.
HOGENOMiHOG000231075.
HOVERGENiHBG074526.

Family and domain databases

InterProiView protein in InterPro
IPR001781. Znf_LIM.
PfamiView protein in Pfam
PF00412. LIM. 3 hits.
SMARTiView protein in SMART
SM00132. LIM. 3 hits.
PROSITEiView protein in PROSITE
PS00478. LIM_DOMAIN_1. 3 hits.
PS50023. LIM_DOMAIN_2. 3 hits.

Sequencei

Sequence statusi: Fragment.

Q5JXI3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAEKFDCHYC RDPLQGKKYV QKDGHHCCLK CFDKFCANTC VECRKPIGAD
60 70 80 90 100
SKEVHYKNRF WHDTCFRCAK CLHPLANETF VAKDNKILCN KCTTREDSPK
110 120 130 140 150
CKGCFKAIVA GDQNVEYKGT VWHKDCFTCS NCKQVIGTGS FFPKGEDFYC
160 170 180 190 200
VTCHETKFAK HCVKCNKAIT SGGITYQDQP WHADCFVCVT CSKKLAGQRF

TAVEDQY
Length:207
Mass (Da):23,617
Last modified:February 15, 2005 - v1
Checksum:i8E33E575B33C9CC0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei207Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL078638 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000434885; ENSP00000413798; ENSG00000022267.
ENST00000452016; ENSP00000408038; ENSG00000022267.
UCSCiuc065bgy.1. human.

Similar proteinsi

Entry informationi

Entry nameiQ5JXI3_HUMAN
AccessioniPrimary (citable) accession number: Q5JXI3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: October 25, 2017
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported