Q5JWF8 (ACL10_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Actin-like protein 10

Gene names

Name:	ACTL10
Synonyms:	C20orf134

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	245 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the actin family.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 245	245	Actin-like protein 10		PRO_0000232865

Sequences

	Sequence		Length	Mass (Da)
	Q5JWF8 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: 06EC6260DF9CC2EE	FASTA	245	26,751
	10 20 30 40 50 60 MASTALLALC STGAFSGLAV EAGAGVCHAT PIYAGHSWHQ ATFRLNVAGS TLSRYLRDLL 70 80 90 100 110 120 VAANPDLLQQ ALPRKAITHL KKRSCYVSLD FEGDLRDPAR HHPASFSVGN GCCVCLSSER 130 140 150 160 170 180 FRCPEPIFQP GLLGQAEQGL PALAFRALQK MPKTLRTRLA DTVVLAGGST LFPGFAERLD 190 200 210 220 230 240 KELEAQCRRH GYAALRPHLV AKHGRGMAVW TGGSMVASLH SFQRRWITRA MYQECGSRLL YDVFN

References

[1]	"The DNA sequence and comparative analysis of human chromosome 20." Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J. Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Testis.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL121906 Genomic DNA. Translation: CAI22126.1. CH471077 Genomic DNA. Translation: EAW76309.1. BC137111 mRNA. Translation: AAI37112.1. BC137114 mRNA. Translation: AAI37115.1.
IPI	IPI00333246.
RefSeq	NP_001019846.1. NM_001024675.1.
UniGene	Hs.592151.
3D structure databases
ProteinModelPortal	Q5JWF8.
ModBase	Search...
PTM databases
PhosphoSite	Q5JWF8.
Polymorphism databases
DMDM	74742586.
Proteomic databases
PaxDb	Q5JWF8.
PRIDE	Q5JWF8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000330271; ENSP00000329647; ENSG00000182584.
GeneID	170487.
KEGG	hsa:170487.
UCSC	uc002wzt.3. human.
Organism-specific databases
CTD	170487.
GeneCards	GC20P032255.
HGNC	HGNC:16127. ACTL10.
neXtProt	NX_Q5JWF8.
PharmGKB	PA25676.
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG5277.
HOGENOM	HOG000112029.
InParanoid	Q5JWF8.
OMA	WHEATFR.
OrthoDB	EOG47D9GV.
Gene expression databases
Bgee	Q5JWF8.
CleanEx	HS_C20orf134.
Genevestigator	Q5JWF8.
GermOnline	ENSG00000182584. Homo sapiens.
Family and domain databases
InterPro	IPR004000. Actin-related. [Graphical view]
PANTHER	PTHR11937. PTHR11937. 1 hit.
Pfam	PF00022. Actin. 1 hit. [Graphical view]
SMART	SM00268. ACTIN. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	170487.
NextBio	88949.

Entry information

Entry name

ACL10_HUMAN

Accession

Primary (citable) accession number: Q5JWF8
Secondary accession number(s): B9EH76

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 18, 2006
Last sequence update:	February 15, 2005
Last modified:	May 1, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.