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Q5JWF8 (ACL10_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Actin-like protein 10
Gene names
Name:ACTL10
Synonyms:C20orf134
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length245 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the actin family.

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 245245Actin-like protein 10
PRO_0000232865

Sequences

Sequence LengthMass (Da)Tools
Q5JWF8 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 06EC6260DF9CC2EE

FASTA24526,751
        10         20         30         40         50         60 
MASTALLALC STGAFSGLAV EAGAGVCHAT PIYAGHSWHQ ATFRLNVAGS TLSRYLRDLL 

        70         80         90        100        110        120 
VAANPDLLQQ ALPRKAITHL KKRSCYVSLD FEGDLRDPAR HHPASFSVGN GCCVCLSSER 

       130        140        150        160        170        180 
FRCPEPIFQP GLLGQAEQGL PALAFRALQK MPKTLRTRLA DTVVLAGGST LFPGFAERLD 

       190        200        210        220        230        240 
KELEAQCRRH GYAALRPHLV AKHGRGMAVW TGGSMVASLH SFQRRWITRA MYQECGSRLL 


YDVFN 

« Hide

References

[1]"The DNA sequence and comparative analysis of human chromosome 20."
Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. expand/collapse author list , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Testis.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL121906 Genomic DNA. Translation: CAI22126.1.
CH471077 Genomic DNA. Translation: EAW76309.1.
BC137111 mRNA. Translation: AAI37112.1.
BC137114 mRNA. Translation: AAI37115.1.
CCDSCCDS33463.1.
RefSeqNP_001019846.1. NM_001024675.1.
UniGeneHs.592151.

3D structure databases

ProteinModelPortalQ5JWF8.
SMRQ5JWF8. Positions 5-244.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ5JWF8.

Polymorphism databases

DMDM74742586.

Proteomic databases

MaxQBQ5JWF8.
PaxDbQ5JWF8.
PRIDEQ5JWF8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000330271; ENSP00000329647; ENSG00000182584.
GeneID170487.
KEGGhsa:170487.
UCSCuc002wzt.3. human.

Organism-specific databases

CTD170487.
GeneCardsGC20P032255.
HGNCHGNC:16127. ACTL10.
neXtProtNX_Q5JWF8.
PharmGKBPA25676.
GenAtlasSearch...

Phylogenomic databases

eggNOGCOG5277.
HOGENOMHOG000112029.
InParanoidQ5JWF8.
OMAWMTRAMY.
OrthoDBEOG7HB59X.
PhylomeDBQ5JWF8.
TreeFamTF300361.

Enzyme and pathway databases

SignaLinkQ5JWF8.

Gene expression databases

BgeeQ5JWF8.
CleanExHS_C20orf134.
GenevestigatorQ5JWF8.

Family and domain databases

InterProIPR004000. Actin-related.
[Graphical view]
PANTHERPTHR11937. PTHR11937. 1 hit.
PfamPF00022. Actin. 1 hit.
[Graphical view]
SMARTSM00268. ACTIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi170487.
NextBio88949.
PROQ5JWF8.

Entry information

Entry nameACL10_HUMAN
AccessionPrimary (citable) accession number: Q5JWF8
Secondary accession number(s): B9EH76
Entry history
Integrated into UniProtKB/Swiss-Prot: April 18, 2006
Last sequence update: February 15, 2005
Last modified: July 9, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 20

Human chromosome 20: entries, gene names and cross-references to MIM