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Protein

Actin-like protein 10

Gene

ACTL10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

SignaLinkiQ5JWF8.

Names & Taxonomyi

Protein namesi
Recommended name:
Actin-like protein 10
Gene namesi
Name:ACTL10
Synonyms:C20orf134
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:16127. ACTL10.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25676.

Polymorphism and mutation databases

BioMutaiACTL10.
DMDMi74742586.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 245245Actin-like protein 10PRO_0000232865Add
BLAST

Proteomic databases

MaxQBiQ5JWF8.
PaxDbiQ5JWF8.
PRIDEiQ5JWF8.

PTM databases

PhosphoSiteiQ5JWF8.

Expressioni

Gene expression databases

BgeeiQ5JWF8.
CleanExiHS_C20orf134.
GenevisibleiQ5JWF8. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000329647.

Structurei

3D structure databases

ProteinModelPortaliQ5JWF8.
SMRiQ5JWF8. Positions 5-244.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the actin family.Curated

Phylogenomic databases

eggNOGiCOG5277.
GeneTreeiENSGT00760000119271.
HOGENOMiHOG000112029.
InParanoidiQ5JWF8.
OMAiWMTRAMY.
OrthoDBiEOG7HB59X.
PhylomeDBiQ5JWF8.
TreeFamiTF300361.

Family and domain databases

InterProiIPR004000. Actin.
[Graphical view]
PANTHERiPTHR11937. PTHR11937. 1 hit.
PfamiPF00022. Actin. 1 hit.
[Graphical view]
SMARTiSM00268. ACTIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5JWF8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASTALLALC STGAFSGLAV EAGAGVCHAT PIYAGHSWHQ ATFRLNVAGS
60 70 80 90 100
TLSRYLRDLL VAANPDLLQQ ALPRKAITHL KKRSCYVSLD FEGDLRDPAR
110 120 130 140 150
HHPASFSVGN GCCVCLSSER FRCPEPIFQP GLLGQAEQGL PALAFRALQK
160 170 180 190 200
MPKTLRTRLA DTVVLAGGST LFPGFAERLD KELEAQCRRH GYAALRPHLV
210 220 230 240
AKHGRGMAVW TGGSMVASLH SFQRRWITRA MYQECGSRLL YDVFN
Length:245
Mass (Da):26,751
Last modified:February 15, 2005 - v1
Checksum:i06EC6260DF9CC2EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121906 Genomic DNA. Translation: CAI22126.1.
CH471077 Genomic DNA. Translation: EAW76309.1.
BC137111 mRNA. Translation: AAI37112.1.
BC137114 mRNA. Translation: AAI37115.1.
CCDSiCCDS33463.1.
RefSeqiNP_001019846.1. NM_001024675.1.
UniGeneiHs.592151.

Genome annotation databases

EnsembliENST00000330271; ENSP00000329647; ENSG00000182584.
GeneIDi170487.
KEGGihsa:170487.
UCSCiuc002wzt.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121906 Genomic DNA. Translation: CAI22126.1.
CH471077 Genomic DNA. Translation: EAW76309.1.
BC137111 mRNA. Translation: AAI37112.1.
BC137114 mRNA. Translation: AAI37115.1.
CCDSiCCDS33463.1.
RefSeqiNP_001019846.1. NM_001024675.1.
UniGeneiHs.592151.

3D structure databases

ProteinModelPortaliQ5JWF8.
SMRiQ5JWF8. Positions 5-244.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000329647.

PTM databases

PhosphoSiteiQ5JWF8.

Polymorphism and mutation databases

BioMutaiACTL10.
DMDMi74742586.

Proteomic databases

MaxQBiQ5JWF8.
PaxDbiQ5JWF8.
PRIDEiQ5JWF8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000330271; ENSP00000329647; ENSG00000182584.
GeneIDi170487.
KEGGihsa:170487.
UCSCiuc002wzt.3. human.

Organism-specific databases

CTDi170487.
GeneCardsiGC20P032255.
HGNCiHGNC:16127. ACTL10.
neXtProtiNX_Q5JWF8.
PharmGKBiPA25676.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiCOG5277.
GeneTreeiENSGT00760000119271.
HOGENOMiHOG000112029.
InParanoidiQ5JWF8.
OMAiWMTRAMY.
OrthoDBiEOG7HB59X.
PhylomeDBiQ5JWF8.
TreeFamiTF300361.

Enzyme and pathway databases

SignaLinkiQ5JWF8.

Miscellaneous databases

GenomeRNAii170487.
NextBioi88949.
PROiQ5JWF8.

Gene expression databases

BgeeiQ5JWF8.
CleanExiHS_C20orf134.
GenevisibleiQ5JWF8. HS.

Family and domain databases

InterProiIPR004000. Actin.
[Graphical view]
PANTHERiPTHR11937. PTHR11937. 1 hit.
PfamiPF00022. Actin. 1 hit.
[Graphical view]
SMARTiSM00268. ACTIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The DNA sequence and comparative analysis of human chromosome 20."
    Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
    , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
    Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.

Entry informationi

Entry nameiACL10_HUMAN
AccessioniPrimary (citable) accession number: Q5JWF8
Secondary accession number(s): B9EH76
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 18, 2006
Last sequence update: February 15, 2005
Last modified: June 24, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.