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Protein
Submitted name:

Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

Gene

GNAS

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

GTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortImported
Gene namesi
Name:GNASImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:4392. GNAS.

PTM / Processingi

Proteomic databases

PaxDbiQ5JWE9.
PeptideAtlasiQ5JWE9.
PRIDEiQ5JWE9.

Expressioni

Gene expression databases

BgeeiENSG00000087460.
ExpressionAtlasiQ5JWE9. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000360141.

Structurei

3D structure databases

ProteinModelPortaliQ5JWE9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0099. Eukaryota.
ENOG410XPC4. LUCA.
GeneTreeiENSGT00770000120503.
HOGENOMiHOG000038729.
HOVERGENiHBG063184.

Family and domain databases

Gene3Di1.10.400.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR000367. Gprotein_alpha_S.
IPR001019. Gprotein_alpha_su.
IPR011025. GproteinA_insert.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10218. PTHR10218. 2 hits.
PfamiPF00503. G-alpha. 1 hit.
[Graphical view]
PRINTSiPR00443. GPROTEINAS.
SMARTiSM00275. G_alpha. 1 hit.
[Graphical view]
SUPFAMiSSF47895. SSF47895. 1 hit.
SSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q5JWE9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PKASRSLKVK KVPLAEKRRQ MRKEALEKRA QKRAEKKRSK LIDKQLQDEK
60 70 80 90 100
MGYMCTHRLL LLGAGESGKS TIVKQMRILH VNGFNGEGGE EDPQAARSNS
110 120 130 140 150
DGSEKATKVQ DIKNNLKEAI ETIVAAMSNL VPPVELANPE NQFRVDYILS
160 170 180 190
VMNVPDFDFP PEFYEHAKAL WEDEGVRACY ERSNEYQLID CAQ
Length:193
Mass (Da):21,934
Last modified:February 15, 2005 - v1
Checksum:iD8F84005A0437333
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei193 – 1931Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109840 Genomic DNA. No translation available.
AL121917 Genomic DNA. No translation available.
AL132655 Genomic DNA. No translation available.
KF456967 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000349036; ENSP00000265621; ENSG00000087460.
UCSCiuc061ycb.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109840 Genomic DNA. No translation available.
AL121917 Genomic DNA. No translation available.
AL132655 Genomic DNA. No translation available.
KF456967 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliQ5JWE9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000360141.

Proteomic databases

PaxDbiQ5JWE9.
PeptideAtlasiQ5JWE9.
PRIDEiQ5JWE9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000349036; ENSP00000265621; ENSG00000087460.
UCSCiuc061ycb.1. human.

Organism-specific databases

HGNCiHGNC:4392. GNAS.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0099. Eukaryota.
ENOG410XPC4. LUCA.
GeneTreeiENSGT00770000120503.
HOGENOMiHOG000038729.
HOVERGENiHBG063184.

Miscellaneous databases

ChiTaRSiGNAS. human.

Gene expression databases

BgeeiENSG00000087460.
ExpressionAtlasiQ5JWE9. baseline and differential.

Family and domain databases

Gene3Di1.10.400.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR000367. Gprotein_alpha_S.
IPR001019. Gprotein_alpha_su.
IPR011025. GproteinA_insert.
IPR027417. P-loop_NTPase.
[Graphical view]
PANTHERiPTHR10218. PTHR10218. 2 hits.
PfamiPF00503. G-alpha. 1 hit.
[Graphical view]
PRINTSiPR00443. GPROTEINAS.
SMARTiSM00275. G_alpha. 1 hit.
[Graphical view]
SUPFAMiSSF47895. SSF47895. 1 hit.
SSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5JWE9_HUMAN
AccessioniPrimary (citable) accession number: Q5JWE9
Entry historyi
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: September 7, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.