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Protein
Submitted name:

Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

Gene

GNAS

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortImported
Gene namesi
Name:GNASImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000087460.23
HGNCiHGNC:4392 GNAS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000087460

PTM / Processingi

Proteomic databases

MaxQBiQ5JWE9
PeptideAtlasiQ5JWE9
PRIDEiQ5JWE9

Expressioni

Gene expression databases

BgeeiENSG00000087460
ExpressionAtlasiQ5JWE9 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5JWE9
SMRiQ5JWE9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili109 – 129Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0099 Eukaryota
ENOG410XPC4 LUCA
GeneTreeiENSGT00910000144108
HOGENOMiHOG000038729
HOVERGENiHBG063184

Family and domain databases

Gene3Di1.10.400.10, 1 hit
InterProiView protein in InterPro
IPR000367 Gprotein_alpha_S
IPR001019 Gprotein_alpha_su
IPR011025 GproteinA_insert
IPR027417 P-loop_NTPase
PANTHERiPTHR10218 PTHR10218, 1 hit
PfamiView protein in Pfam
PF00503 G-alpha, 1 hit
PRINTSiPR00443 GPROTEINAS
SMARTiView protein in SMART
SM00275 G_alpha, 1 hit
SUPFAMiSSF47895 SSF47895, 1 hit
SSF52540 SSF52540, 1 hit

Sequencei

Sequence statusi: Fragment.

Q5JWE9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
PKASRSLKVK KVPLAEKRRQ MRKEALEKRA QKRAEKKRSK LIDKQLQDEK
60 70 80 90 100
MGYMCTHRLL LLGAGESGKS TIVKQMRILH VNGFNGEGGE EDPQAARSNS
110 120 130 140 150
DGSEKATKVQ DIKNNLKEAI ETIVAAMSNL VPPVELANPE NQFRVDYILS
160 170 180 190
VMNVPDFDFP PEFYEHAKAL WEDEGVRACY ERSNEYQLID CAQ
Length:193
Mass (Da):21,934
Last modified:February 15, 2005 - v1
Checksum:iD8F84005A0437333
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei193Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL109840 Genomic DNA No translation available.
AL121917 Genomic DNA No translation available.
AL132655 Genomic DNA No translation available.
KF456967 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000349036; ENSP00000265621; ENSG00000087460
UCSCiuc061ycb.1 human

Similar proteinsi

Entry informationi

Entry nameiQ5JWE9_HUMAN
AccessioniPrimary (citable) accession number: Q5JWE9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: March 28, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health