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Protein
Submitted name:

Double-stranded RNA-binding protein Staufen homolog 1

Gene

STAU1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Double-stranded RNA-binding protein Staufen homolog 1Imported
Gene namesi
Name:STAU1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:11370. STAU1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000124214.

PTM / Processingi

Proteomic databases

MaxQBiQ5JW30.
PaxDbiQ5JW30.
PeptideAtlasiQ5JW30.
PRIDEiQ5JW30.

Expressioni

Gene expression databases

BgeeiENSG00000124214.
ExpressionAtlasiQ5JW30. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiQ5JW30. 1 interactor.
STRINGi9606.ENSP00000360922.

Structurei

3D structure databases

ProteinModelPortaliQ5JW30.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini46 – 81DRBM (double-stranded RNA-binding)InterPro annotationAdd BLAST36
Domaini103 – 170DRBM (double-stranded RNA-binding)InterPro annotationAdd BLAST68
Domaini203 – 271DRBM (double-stranded RNA-binding)InterPro annotationAdd BLAST69

Phylogenomic databases

eggNOGiKOG3732. Eukaryota.
ENOG410XSCK. LUCA.
GeneTreeiENSGT00830000128290.
HOGENOMiHOG000231025.
HOVERGENiHBG005013.

Family and domain databases

Gene3Di3.30.160.20. 3 hits.
InterProiIPR014720. dsRBD_dom.
IPR032478. Staufen_C.
[Graphical view]
PfamiPF00035. dsrm. 3 hits.
PF16482. Staufen_C. 1 hit.
[Graphical view]
SMARTiSM00358. DSRM. 3 hits.
[Graphical view]
PROSITEiPS50137. DS_RBD. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5JW30-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLGKKPMYK PVDPYSRMQS TYNYNMRGGA YPPRYFYPFP VPPLLYQVEL
60 70 80 90 100
SVGGQQFNGK GKTRQAAKHD AAAKALRILQ NEPLPERLEV NGRESEEENL
110 120 130 140 150
NKSEISQVFE IALKRNLPVN FEVARESGPP HMKNFVTKVS VGEFVGEGEG
160 170 180 190 200
KSKKISKKNA AIAVLEELKK LPPLPAVERV KPRIKKKTKP IVKTSPEYGQ
210 220 230 240 250
GINPISRLAQ IQQAKKEKEP EYTLLTERGL PRRREFVMQV KVGNHTAEGT
260 270 280 290 300
GTNKKVAKRN AAENMLEILG FKVPQAQPTK PALKSEEKTP IKKPGDGRKV
310 320 330 340 350
TFFEPGSGDE NGTSNKEDEF RMPYLSHQQL PAGILPMVPE VAQAVGVSQG
360 370 380 390 400
HHTKDFTRAA PNPAKATVTA MIARELLYGG TSPTAETILK NNISSGHVPH
410 420 430 440 450
GPLTRPSEQL DYLSRVQGFQ VEYKDFPKNN KNEFVSLINC SSQPPLISHG
460 470 480 490
IGKDVESCHD MAALNILKLL SELDQQSTEM PRTGNGPMSV CGRC
Length:494
Mass (Da):54,709
Last modified:February 15, 2005 - v1
Checksum:i30E8C846636AFBBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL133174 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000371792; ENSP00000360857; ENSG00000124214.
UCSCiuc061xpn.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL133174 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliQ5JW30.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ5JW30. 1 interactor.
STRINGi9606.ENSP00000360922.

Proteomic databases

MaxQBiQ5JW30.
PaxDbiQ5JW30.
PeptideAtlasiQ5JW30.
PRIDEiQ5JW30.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000371792; ENSP00000360857; ENSG00000124214.
UCSCiuc061xpn.1. human.

Organism-specific databases

HGNCiHGNC:11370. STAU1.
OpenTargetsiENSG00000124214.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3732. Eukaryota.
ENOG410XSCK. LUCA.
GeneTreeiENSGT00830000128290.
HOGENOMiHOG000231025.
HOVERGENiHBG005013.

Miscellaneous databases

ChiTaRSiSTAU1. human.

Gene expression databases

BgeeiENSG00000124214.
ExpressionAtlasiQ5JW30. baseline and differential.

Family and domain databases

Gene3Di3.30.160.20. 3 hits.
InterProiIPR014720. dsRBD_dom.
IPR032478. Staufen_C.
[Graphical view]
PfamiPF00035. dsrm. 3 hits.
PF16482. Staufen_C. 1 hit.
[Graphical view]
SMARTiSM00358. DSRM. 3 hits.
[Graphical view]
PROSITEiPS50137. DS_RBD. 3 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5JW30_HUMAN
AccessioniPrimary (citable) accession number: Q5JW30
Entry historyi
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: November 30, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.