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Protein
Submitted name:

Double-stranded RNA-binding protein Staufen homolog 1

Gene

STAU1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Double-stranded RNA-binding protein Staufen homolog 1Imported
Gene namesi
Name:STAU1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000124214.19.
HGNCiHGNC:11370. STAU1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000124214.

PTM / Processingi

Proteomic databases

MaxQBiQ5JW30.
PaxDbiQ5JW30.
PeptideAtlasiQ5JW30.
PRIDEiQ5JW30.

Expressioni

Gene expression databases

BgeeiENSG00000124214.
ExpressionAtlasiQ5JW30. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiQ5JW30. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliQ5JW30.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini46 – 81DRBMInterPro annotationAdd BLAST36
Domaini103 – 170DRBMInterPro annotationAdd BLAST68
Domaini203 – 271DRBMInterPro annotationAdd BLAST69

Phylogenomic databases

eggNOGiKOG3732. Eukaryota.
ENOG410XSCK. LUCA.
GeneTreeiENSGT00900000140998.
HOGENOMiHOG000231025.
HOVERGENiHBG005013.

Family and domain databases

InterProiView protein in InterPro
IPR014720. dsRBD_dom.
IPR032478. Staufen_C.
PfamiView protein in Pfam
PF00035. dsrm. 3 hits.
PF16482. Staufen_C. 1 hit.
SMARTiView protein in SMART
SM00358. DSRM. 3 hits.
PROSITEiView protein in PROSITE
PS50137. DS_RBD. 3 hits.

Sequencei

Sequence statusi: Complete.

Q5JW30-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLGKKPMYK PVDPYSRMQS TYNYNMRGGA YPPRYFYPFP VPPLLYQVEL
60 70 80 90 100
SVGGQQFNGK GKTRQAAKHD AAAKALRILQ NEPLPERLEV NGRESEEENL
110 120 130 140 150
NKSEISQVFE IALKRNLPVN FEVARESGPP HMKNFVTKVS VGEFVGEGEG
160 170 180 190 200
KSKKISKKNA AIAVLEELKK LPPLPAVERV KPRIKKKTKP IVKTSPEYGQ
210 220 230 240 250
GINPISRLAQ IQQAKKEKEP EYTLLTERGL PRRREFVMQV KVGNHTAEGT
260 270 280 290 300
GTNKKVAKRN AAENMLEILG FKVPQAQPTK PALKSEEKTP IKKPGDGRKV
310 320 330 340 350
TFFEPGSGDE NGTSNKEDEF RMPYLSHQQL PAGILPMVPE VAQAVGVSQG
360 370 380 390 400
HHTKDFTRAA PNPAKATVTA MIARELLYGG TSPTAETILK NNISSGHVPH
410 420 430 440 450
GPLTRPSEQL DYLSRVQGFQ VEYKDFPKNN KNEFVSLINC SSQPPLISHG
460 470 480 490
IGKDVESCHD MAALNILKLL SELDQQSTEM PRTGNGPMSV CGRC
Length:494
Mass (Da):54,709
Last modified:February 15, 2005 - v1
Checksum:i30E8C846636AFBBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL133174 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000371792; ENSP00000360857; ENSG00000124214.
UCSCiuc061xpn.1. human.

Similar proteinsi

Entry informationi

Entry nameiQ5JW30_HUMAN
AccessioniPrimary (citable) accession number: Q5JW30
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: October 25, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported