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Protein
Submitted name:

E3 ubiquitin-protein ligase TRIM32

Gene

TRIM32

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
E3 ubiquitin-protein ligase TRIM32Imported
Gene namesi
Name:TRIM32Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:16380. TRIM32.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000119401.

PTM / Processingi

Proteomic databases

EPDiQ5JVY0.
MaxQBiQ5JVY0.
PaxDbiQ5JVY0.
PeptideAtlasiQ5JVY0.
PRIDEiQ5JVY0.

Expressioni

Gene expression databases

BgeeiENSG00000119401.
ExpressionAtlasiQ5JVY0. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiQ5JVY0. 1 interactor.
MINTiMINT-1461567.
STRINGi9606.ENSP00000363095.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 65RING-typeInterPro annotationAdd BLAST46
Domaini95 – 138B box-typeInterPro annotationAdd BLAST44

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili139 – 172Sequence analysisAdd BLAST34

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiENOG410ITFD. Eukaryota.
ENOG410XRCH. LUCA.
GeneTreeiENSGT00550000074377.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR033569. TRIM32.
IPR027370. Znf-RING_LisH.
IPR000315. Znf_B-box.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
[Graphical view]
PANTHERiPTHR24103:SF363. PTHR24103:SF363. 1 hit.
PfamiPF00643. zf-B_box. 1 hit.
PF13445. zf-RING_UBOX. 1 hit.
[Graphical view]
SMARTiSM00336. BBOX. 1 hit.
SM00184. RING. 1 hit.
[Graphical view]
PROSITEiPS50119. ZF_BBOX. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q5JVY0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAAAASHLN LDALREVLEC PICMESFTEE QLRPKLLHCG HTICRQCLEK
60 70 80 90 100
LLASSINGVR CPFCSKITRI TSLTQLTDNL TVLKIIDTAG LSEAVGLLMC
110 120 130 140 150
RSCGRRLPRQ FCRSCGLVLC EPCREADHQP PGHCTLPVKE AAEERRRDFG
160 170
EKLTRLRELM GELQRRKAAL EG
Length:172
Mass (Da):19,188
Last modified:October 5, 2016 - v8
Checksum:i451BD2F93895FB1F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei172Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL133284 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000411410; ENSP00000412603; ENSG00000119401.
UCSCiuc064vhp.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL133284 Genomic DNA. No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ5JVY0. 1 interactor.
MINTiMINT-1461567.
STRINGi9606.ENSP00000363095.

Proteomic databases

EPDiQ5JVY0.
MaxQBiQ5JVY0.
PaxDbiQ5JVY0.
PeptideAtlasiQ5JVY0.
PRIDEiQ5JVY0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000411410; ENSP00000412603; ENSG00000119401.
UCSCiuc064vhp.1. human.

Organism-specific databases

HGNCiHGNC:16380. TRIM32.
OpenTargetsiENSG00000119401.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410ITFD. Eukaryota.
ENOG410XRCH. LUCA.
GeneTreeiENSGT00550000074377.

Gene expression databases

BgeeiENSG00000119401.
ExpressionAtlasiQ5JVY0. baseline and differential.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
InterProiIPR033569. TRIM32.
IPR027370. Znf-RING_LisH.
IPR000315. Znf_B-box.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
[Graphical view]
PANTHERiPTHR24103:SF363. PTHR24103:SF363. 1 hit.
PfamiPF00643. zf-B_box. 1 hit.
PF13445. zf-RING_UBOX. 1 hit.
[Graphical view]
SMARTiSM00336. BBOX. 1 hit.
SM00184. RING. 1 hit.
[Graphical view]
PROSITEiPS50119. ZF_BBOX. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5JVY0_HUMAN
AccessioniPrimary (citable) accession number: Q5JVY0
Entry historyi
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: October 5, 2016
Last modified: November 30, 2016
This is version 96 of the entry and version 8 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.