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Protein

Testis-expressed sequence 30 protein

Gene

TEX30

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Testis-expressed sequence 30 protein
Gene namesi
Name:TEX30
Synonyms:C13orf27
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 13

Organism-specific databases

HGNCiHGNC:25188. TEX30.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA147358470.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 227227Testis-expressed sequence 30 proteinPRO_0000274312Add
BLAST

Proteomic databases

MaxQBiQ5JUR7.
PaxDbiQ5JUR7.
PRIDEiQ5JUR7.

PTM databases

PhosphoSiteiQ5JUR7.

Expressioni

Gene expression databases

BgeeiQ5JUR7.
CleanExiHS_C13orf27.
ExpressionAtlasiQ5JUR7. baseline and differential.
GenevestigatoriQ5JUR7.

Organism-specific databases

HPAiHPA053545.

Interactioni

Protein-protein interaction databases

BioGridi124998. 3 interactions.
STRINGi9606.ENSP00000365199.

Structurei

3D structure databases

ProteinModelPortaliQ5JUR7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG3571.
GeneTreeiENSGT00390000016489.
HOGENOMiHOG000006654.
HOVERGENiHBG081256.
InParanoidiQ5JUR7.
OMAiYPLHRPK.
OrthoDBiEOG7DC25Q.
PhylomeDBiQ5JUR7.
TreeFamiTF332335.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR029059. AB_hydrolase_5.
IPR026555. NSL3/Tex30.
[Graphical view]
PANTHERiPTHR13136. PTHR13136. 1 hit.
PfamiPF12695. Abhydrolase_5. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q5JUR7-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSHTEVKLKI PFGNKLLDAV CLVPNKSLTY GIILTHGASG DMNLPHLMSL
60 70 80 90 100
ASHLASHGFF CLRFTCKGLN IVHRIKAYKS VLNYLKTSGE YKLAGVFLGG
110 120 130 140 150
RSMGSRAAAS VMCHIEPDDG DDFVRGLICI SYPLHHPKQQ HKLRDEDLFR
160 170 180 190 200
LKEPVLFVSG SADEMCEKNL LEKVAQKMQA PHKIHWIEKA NHSMAVKGRS
210 220
TNDVFKEINT QILFWIQEIT EMDKKCH
Length:227
Mass (Da):25,585
Last modified:February 15, 2005 - v1
Checksum:iB37C06A38A91E774
GO
Isoform 2 (identifier: Q5JUR7-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     100-113: GRSMGSRAAASVMC → ELVGESGTENASSP
     114-227: Missing.

Note: No experimental confirmation available. Gene prediction based on EST data.

Show »
Length:113
Mass (Da):12,220
Checksum:i6C724738FA56E3E2
GO

Sequence cautioni

The sequence AAH15148.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei100 – 11314GRSMG…ASVMC → ELVGESGTENASSP in isoform 2. CuratedVSP_055706Add
BLAST
Alternative sequencei114 – 227114Missing in isoform 2. CuratedVSP_055707Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL157769 Genomic DNA. No translation available.
BC015148 mRNA. Translation: AAH15148.2. Different initiation.
CCDSiCCDS66578.1. [Q5JUR7-2]
CCDS9503.2. [Q5JUR7-1]
RefSeqiNP_001273704.1. NM_001286775.1. [Q5JUR7-2]
NP_001273705.1. NM_001286776.1.
NP_620134.3. NM_138779.4. [Q5JUR7-1]
XP_005254154.1. XM_005254097.1. [Q5JUR7-1]
UniGeneiHs.398111.

Genome annotation databases

EnsembliENST00000376019; ENSP00000365187; ENSG00000151287.
ENST00000376021; ENSP00000365189; ENSG00000151287.
ENST00000376027; ENSP00000365195; ENSG00000151287. [Q5JUR7-2]
ENST00000376029; ENSP00000365197; ENSG00000151287. [Q5JUR7-2]
ENST00000376032; ENSP00000365200; ENSG00000151287. [Q5JUR7-1]
GeneIDi93081.
KEGGihsa:93081.
UCSCiuc001vpn.3. human. [Q5JUR7-1]

Polymorphism databases

DMDMi74742331.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL157769 Genomic DNA. No translation available.
BC015148 mRNA. Translation: AAH15148.2. Different initiation.
CCDSiCCDS66578.1. [Q5JUR7-2]
CCDS9503.2. [Q5JUR7-1]
RefSeqiNP_001273704.1. NM_001286775.1. [Q5JUR7-2]
NP_001273705.1. NM_001286776.1.
NP_620134.3. NM_138779.4. [Q5JUR7-1]
XP_005254154.1. XM_005254097.1. [Q5JUR7-1]
UniGeneiHs.398111.

3D structure databases

ProteinModelPortaliQ5JUR7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi124998. 3 interactions.
STRINGi9606.ENSP00000365199.

Chemistry

ChEMBLiCHEMBL2189125.

PTM databases

PhosphoSiteiQ5JUR7.

Polymorphism databases

DMDMi74742331.

Proteomic databases

MaxQBiQ5JUR7.
PaxDbiQ5JUR7.
PRIDEiQ5JUR7.

Protocols and materials databases

DNASUi93081.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000376019; ENSP00000365187; ENSG00000151287.
ENST00000376021; ENSP00000365189; ENSG00000151287.
ENST00000376027; ENSP00000365195; ENSG00000151287. [Q5JUR7-2]
ENST00000376029; ENSP00000365197; ENSG00000151287. [Q5JUR7-2]
ENST00000376032; ENSP00000365200; ENSG00000151287. [Q5JUR7-1]
GeneIDi93081.
KEGGihsa:93081.
UCSCiuc001vpn.3. human. [Q5JUR7-1]

Organism-specific databases

CTDi93081.
GeneCardsiGC13M103419.
HGNCiHGNC:25188. TEX30.
HPAiHPA053545.
neXtProtiNX_Q5JUR7.
PharmGKBiPA147358470.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiCOG3571.
GeneTreeiENSGT00390000016489.
HOGENOMiHOG000006654.
HOVERGENiHBG081256.
InParanoidiQ5JUR7.
OMAiYPLHRPK.
OrthoDBiEOG7DC25Q.
PhylomeDBiQ5JUR7.
TreeFamiTF332335.

Miscellaneous databases

GenomeRNAii93081.
NextBioi35539295.
PROiQ5JUR7.

Gene expression databases

BgeeiQ5JUR7.
CleanExiHS_C13orf27.
ExpressionAtlasiQ5JUR7. baseline and differential.
GenevestigatoriQ5JUR7.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR029059. AB_hydrolase_5.
IPR026555. NSL3/Tex30.
[Graphical view]
PANTHERiPTHR13136. PTHR13136. 1 hit.
PfamiPF12695. Abhydrolase_5. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The DNA sequence and analysis of human chromosome 13."
    Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L., Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P., Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L., Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S., Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T.
    Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Testis.

Entry informationi

Entry nameiTEX30_HUMAN
AccessioniPrimary (citable) accession number: Q5JUR7
Secondary accession number(s): Q5JUR8, Q96KZ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: February 15, 2005
Last modified: January 7, 2015
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 13
    Human chromosome 13: entries, gene names and cross-references to MIM

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.