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Protein

P antigen family member 3

Gene

PAGE3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciZFISH:G66-33774-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
P antigen family member 3
Short name:
PAGE-3
Alternative name(s):
G antigen family D member 1
Prostate-associated gene 3 protein
Gene namesi
Name:PAGE3
Synonyms:GAGED1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

HGNCiHGNC:4110. PAGE3.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000204279.

Polymorphism and mutation databases

DMDMi74742310.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002473601 – 113P antigen family member 3Add BLAST113

Proteomic databases

PaxDbiQ5JUK9.
PRIDEiQ5JUK9.

Expressioni

Gene expression databases

BgeeiENSG00000204279.
CleanExiHS_PAGE3.

Organism-specific databases

HPAiHPA062248.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
FAM9BQ8IZU03EBI-10244544,EBI-10175124
MEOX1P502213EBI-10244544,EBI-2864512

Protein-protein interaction databases

IntActiQ5JUK9. 2 interactors.

Structurei

3D structure databases

ProteinModelPortaliQ5JUK9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GAGE family.Curated

Phylogenomic databases

eggNOGiENOG410JGTD. Eukaryota.
ENOG4111340. LUCA.
GeneTreeiENSGT00840000129979.
HOGENOMiHOG000237345.
HOVERGENiHBG099032.
InParanoidiQ5JUK9.
OMAiAYLWELT.
OrthoDBiEOG091G0Z0U.
PhylomeDBiQ5JUK9.
TreeFamiTF340669.

Family and domain databases

InterProiIPR031320. GAGE.
IPR008625. GAGE_fam.
[Graphical view]
PANTHERiPTHR14047. PTHR14047. 1 hit.
PfamiPF05831. GAGE. 1 hit.
[Graphical view]
SMARTiSM01379. GAGE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5JUK9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGHQRTRSR SRERRDDQDS NHPVGAVVAQ ELPSNDQLQQ EEPPIESQDY
60 70 80 90 100
TPGQERDEGA LDFQVLGLAA YLWELTRSKT GGERGDGPNV KGEFLPNLEP
110
VKIPEAGEGQ PSV
Length:113
Mass (Da):12,480
Last modified:February 15, 2005 - v1
Checksum:iD46910FC698E09B2
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_02709735N → D.2 PublicationsCorresponds to variant rs4826381dbSNPEnsembl.1
Natural variantiVAR_02709853G → S.Corresponds to variant rs2296807dbSNPEnsembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL158819 Genomic DNA. Translation: CAI40488.1.
CH471154 Genomic DNA. Translation: EAW93220.1.
BC140001 mRNA. Translation: AAI40002.1.
BC140741 mRNA. Translation: AAI40742.1.
BC144449 mRNA. Translation: AAI44450.1.
CCDSiCCDS35307.1.
RefSeqiNP_001017931.2. NM_001017931.2.
NP_001164723.1. NM_001171252.1.
NP_001290542.1. NM_001303613.1.
XP_016884771.1. XM_017029282.1.
UniGeneiHs.163473.

Genome annotation databases

EnsembliENST00000374951; ENSP00000364089; ENSG00000204279.
ENST00000519203; ENSP00000429571; ENSG00000204279.
GeneIDi139793.
KEGGihsa:139793.
UCSCiuc022bxs.4. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL158819 Genomic DNA. Translation: CAI40488.1.
CH471154 Genomic DNA. Translation: EAW93220.1.
BC140001 mRNA. Translation: AAI40002.1.
BC140741 mRNA. Translation: AAI40742.1.
BC144449 mRNA. Translation: AAI44450.1.
CCDSiCCDS35307.1.
RefSeqiNP_001017931.2. NM_001017931.2.
NP_001164723.1. NM_001171252.1.
NP_001290542.1. NM_001303613.1.
XP_016884771.1. XM_017029282.1.
UniGeneiHs.163473.

3D structure databases

ProteinModelPortaliQ5JUK9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ5JUK9. 2 interactors.

Polymorphism and mutation databases

DMDMi74742310.

Proteomic databases

PaxDbiQ5JUK9.
PRIDEiQ5JUK9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000374951; ENSP00000364089; ENSG00000204279.
ENST00000519203; ENSP00000429571; ENSG00000204279.
GeneIDi139793.
KEGGihsa:139793.
UCSCiuc022bxs.4. human.

Organism-specific databases

CTDi139793.
GeneCardsiPAGE3.
HGNCiHGNC:4110. PAGE3.
HPAiHPA062248.
MIMi300739. gene.
neXtProtiNX_Q5JUK9.
OpenTargetsiENSG00000204279.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410JGTD. Eukaryota.
ENOG4111340. LUCA.
GeneTreeiENSGT00840000129979.
HOGENOMiHOG000237345.
HOVERGENiHBG099032.
InParanoidiQ5JUK9.
OMAiAYLWELT.
OrthoDBiEOG091G0Z0U.
PhylomeDBiQ5JUK9.
TreeFamiTF340669.

Enzyme and pathway databases

BioCyciZFISH:G66-33774-MONOMER.

Miscellaneous databases

GenomeRNAii139793.
PROiQ5JUK9.
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000204279.
CleanExiHS_PAGE3.

Family and domain databases

InterProiIPR031320. GAGE.
IPR008625. GAGE_fam.
[Graphical view]
PANTHERiPTHR14047. PTHR14047. 1 hit.
PfamiPF05831. GAGE. 1 hit.
[Graphical view]
SMARTiSM01379. GAGE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPAGE3_HUMAN
AccessioniPrimary (citable) accession number: Q5JUK9
Secondary accession number(s): A5D6Y1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: February 15, 2005
Last modified: November 2, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.