ID   Q5JTQ9_HUMAN            Unreviewed;       135 AA.
AC   Q5JTQ9;
DT   15-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2005, sequence version 1.
DT   27-MAR-2024, entry version 104.
DE   SubName: Full=Catenin alpha like 1 {ECO:0000313|Ensembl:ENSP00000363722.1};
GN   Name=CTNNAL1 {ECO:0000313|Ensembl:ENSP00000363722.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000363722.1, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000363722.1, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15164053; DOI=10.1038/nature02465;
RA   Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L.,
RA   Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R.,
RA   Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S.,
RA   Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K.,
RA   Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y.,
RA   Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C.,
RA   Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E.,
RA   Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M.,
RA   Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J.,
RA   Frankish A., Frankland J.A., French L., Fricker D.G., Garner P.,
RA   Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S.,
RA   Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E.,
RA   Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D.,
RA   Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E.,
RA   Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K.,
RA   Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S.,
RA   Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J.,
RA   Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E.,
RA   McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V.,
RA   Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S.,
RA   Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K.,
RA   Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J.,
RA   Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M.,
RA   West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L.,
RA   Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.,
RA   Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J.,
RA   Dunham I.;
RT   "DNA sequence and analysis of human chromosome 9.";
RL   Nature 429:369-374(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000363722.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AL354797; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; Q5JTQ9; -.
DR   SMR; Q5JTQ9; -.
DR   MassIVE; Q5JTQ9; -.
DR   MaxQB; Q5JTQ9; -.
DR   PeptideAtlas; Q5JTQ9; -.
DR   ProteomicsDB; 63228; -.
DR   Antibodypedia; 14981; 166 antibodies from 27 providers.
DR   Ensembl; ENST00000374594.1; ENSP00000363722.1; ENSG00000119326.15.
DR   UCSC; uc064uze.1; human.
DR   HGNC; HGNC:2512; CTNNAL1.
DR   VEuPathDB; HostDB:ENSG00000119326; -.
DR   GeneTree; ENSGT01030000234543; -.
DR   HOGENOM; CLU_1885076_0_0_1; -.
DR   OMA; DQQKMAK; -.
DR   ChiTaRS; CTNNAL1; human.
DR   Proteomes; UP000005640; Chromosome 9.
DR   Bgee; ENSG00000119326; Expressed in right adrenal gland cortex and 208 other cell types or tissues.
DR   ExpressionAtlas; Q5JTQ9; baseline and differential.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   GO; GO:0007266; P:Rho protein signal transduction; IEA:InterPro.
DR   Gene3D; 1.20.120.230; Alpha-catenin/vinculin-like; 1.
DR   InterPro; IPR036723; Alpha-catenin/vinculin-like_sf.
DR   InterPro; IPR030045; CTNNAL1.
DR   PANTHER; PTHR46342; ALPHA-CATULIN; 1.
DR   PANTHER; PTHR46342:SF1; ALPHA-CATULIN; 1.
DR   SUPFAM; SSF47220; alpha-catenin/vinculin-like; 1.
PE   1: Evidence at protein level;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Proteomics identification {ECO:0007829|EPD:Q5JTQ9,
KW   ECO:0007829|MaxQB:Q5JTQ9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
SQ   SEQUENCE   135 AA;  15332 MW;  8CDBCFA811E64ADC CRC64;
     MSSMAYSLYL FTRGEGPLKT SQDLIHQLEV FAAEGLKLTS SVQAFSKQLK DDDKLMLLLE
     INKLIPLCHQ LQTVTKTSLQ NKVFLKVDKC ITKTRSMMAL LVQLLSLCYK LLKKLQMENN
     GWVSVTNKDT MDSKT
//