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Protein

Tight junction-associated protein 1

Gene

TJAP1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Tight junction-associated protein 1
Alternative name(s):
Protein incorporated later into tight junctions
Tight junction protein 4
Gene namesi
Name:TJAP1
Synonyms:PILT, TJP4
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

HGNCiHGNC:17949. TJAP1.

Subcellular locationi

  • Golgi apparatus By similarity
  • Cell junctiontight junction By similarity

  • Note: Recruited to tight junctions (TJ) during late stages of maturation of the TJ complexes. Excluded from adherens junctions and desmosomes (By similarity).By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Golgi apparatus, Tight junction

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA38268.

Polymorphism and mutation databases

BioMutaiTJAP1.
DMDMi74742134.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedCombined sources
Chaini2 – 557556Tight junction-associated protein 1PRO_0000072550Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylthreonineCombined sources
Modified residuei300 – 3001PhosphoserineCombined sources
Modified residuei318 – 3181PhosphothreonineCombined sources
Modified residuei320 – 3201PhosphoserineCombined sources
Modified residuei345 – 3451PhosphoserineCombined sources
Modified residuei422 – 4221PhosphothreonineCombined sources
Modified residuei491 – 4911PhosphoserineCombined sources
Modified residuei545 – 5451PhosphoserineCombined sources

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ5JTD0.
MaxQBiQ5JTD0.
PaxDbiQ5JTD0.
PeptideAtlasiQ5JTD0.
PRIDEiQ5JTD0.

PTM databases

iPTMnetiQ5JTD0.
PhosphoSiteiQ5JTD0.

Expressioni

Tissue specificityi

Ubiquitously expressed.1 Publication

Gene expression databases

BgeeiQ5JTD0.
CleanExiHS_TJAP1.
ExpressionAtlasiQ5JTD0. baseline and differential.
GenevisibleiQ5JTD0. HS.

Organism-specific databases

HPAiHPA030164.
HPA030165.
HPA030166.

Interactioni

Subunit structurei

Interacts with DLG1.1 Publication

Protein-protein interaction databases

BioGridi125043. 19 interactions.
IntActiQ5JTD0. 14 interactions.
STRINGi9606.ENSP00000361522.

Structurei

3D structure databases

ProteinModelPortaliQ5JTD0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili36 – 175140Sequence analysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi271 – 32757Pro-richAdd
BLAST

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IJKM. Eukaryota.
ENOG410Z76C. LUCA.
GeneTreeiENSGT00530000063778.
HOVERGENiHBG056279.
InParanoidiQ5JTD0.
KOiK06105.
OMAiMSEGVPG.
OrthoDBiEOG7JT6VT.
PhylomeDBiQ5JTD0.
TreeFamiTF331612.

Family and domain databases

InterProiIPR028179. Tjap1.
[Graphical view]
PANTHERiPTHR28664:SF3. PTHR28664:SF3. 1 hit.
PfamiPF15453. Pilt. 2 hits.
[Graphical view]

Sequences (4)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 4 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q5JTD0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MTSAAPAKKP YRKAPPEHRE LRLEIPGSRL EQEEPLTDAE RMKLLQEENE
60 70 80 90 100
ELRRRLASAT RRTEALEREL EIGQDCLELE LGQSREELDK FKDKFRRLQN
110 120 130 140 150
SYTASQRTNQ ELEDKLHTLA SLSHSWIFAI KKAEMDRKTL DWEIVELTNK
160 170 180 190 200
LLDAKNTINK LEELNERYRL DCNLAVQLLK CNKSHFRNHK FADLPCELQD
210 220 230 240 250
MVRKHLHSGQ EAASPGPAPS LAPGAVVPTS VIARVLEKPE SLLLNSAQSG
260 270 280 290 300
SAGRPLAEDV FVHVDMSEGV PGDPASPPAP GSPTPQPNGE CHSLGTARGS
310 320 330 340 350
PEEELPLPAF EKLNPYPTPS PPHPLYPGRR VIEFSEDKVR IPRNSPLPNC
360 370 380 390 400
TYATRQAISL SLVEEGSERA RPSPVPSTPA SAQASPHHQP SPAPLTLSAP
410 420 430 440 450
ASSASSEEDL LVSWQRAFVD RTPPPAAVAQ RTAFGRDALP ELQRHFAHSP
460 470 480 490 500
ADRDEVVQAP SARPEESELL LPTEPDSGFP REEEELNLPI SPEEERQSLL
510 520 530 540 550
PINRGTEEGP GTSHTEGRAW PLPSSSRPQR SPKRMGVHHL HRKDSLTQAQ

EQGNLLN
Note: No experimental confirmation available.
Length:557
Mass (Da):61,821
Last modified:February 15, 2005 - v1
Checksum:i07D41B72E1CB0E20
GO
Isoform 2 (identifier: Q5JTD0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     120-129: Missing.

Show »
Length:547
Mass (Da):60,721
Checksum:i25EEC24A2CAE1789
GO
Isoform 3 (identifier: Q5JTD0-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     44-557: Missing.

Note: No experimental confirmation available.
Show »
Length:43
Mass (Da):4,959
Checksum:iC9195BEA9B859982
GO
Isoform 4 (identifier: Q5JTD0-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-65: Missing.
     66-66: L → M
     120-129: Missing.

Note: No experimental confirmation available.
Show »
Length:482
Mass (Da):53,174
Checksum:i7A8B2B9A850B9DBE
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti174 – 1741L → P in BAB14867 (PubMed:14702039).Curated
Sequence conflicti185 – 1862HF → QV in CAI46221 (PubMed:17974005).Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 6565Missing in isoform 4. 1 PublicationVSP_015999Add
BLAST
Alternative sequencei44 – 557514Missing in isoform 3. 1 PublicationVSP_016000Add
BLAST
Alternative sequencei66 – 661L → M in isoform 4. 1 PublicationVSP_016001
Alternative sequencei120 – 12910Missing in isoform 2 and isoform 4. 3 PublicationsVSP_016002

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK024269 mRNA. Translation: BAB14867.1.
CR749480 mRNA. Translation: CAH18308.1.
AL117398 Transcribed RNA. Translation: CAI46221.1.
AL355802 Genomic DNA. Translation: CAI42617.1.
AL355802 Genomic DNA. Translation: CAI42618.1.
AL355802 Genomic DNA. Translation: CAI42619.1.
BC046239 mRNA. Translation: AAH46239.1.
BC064401 mRNA. Translation: AAH64401.1.
CCDSiCCDS4898.1. [Q5JTD0-2]
CCDS55004.1. [Q5JTD0-1]
RefSeqiNP_001139488.1. NM_001146016.1. [Q5JTD0-1]
NP_001139489.1. NM_001146017.1. [Q5JTD0-1]
NP_001139490.1. NM_001146018.1. [Q5JTD0-2]
NP_001139491.1. NM_001146019.1. [Q5JTD0-2]
NP_001139492.1. NM_001146020.1. [Q5JTD0-2]
NP_542171.2. NM_080604.2. [Q5JTD0-2]
XP_006715312.1. XM_006715249.1. [Q5JTD0-1]
XP_006715313.1. XM_006715250.2. [Q5JTD0-1]
XP_006715314.1. XM_006715251.2. [Q5JTD0-1]
XP_006715315.1. XM_006715252.2. [Q5JTD0-1]
XP_006715316.1. XM_006715253.2. [Q5JTD0-1]
XP_006715317.1. XM_006715254.2. [Q5JTD0-1]
XP_006715319.1. XM_006715256.1. [Q5JTD0-1]
XP_006715320.1. XM_006715257.2. [Q5JTD0-1]
XP_006715321.1. XM_006715258.2. [Q5JTD0-1]
XP_006715322.1. XM_006715259.2. [Q5JTD0-1]
XP_006715323.1. XM_006715260.1. [Q5JTD0-1]
XP_006715324.1. XM_006715261.1. [Q5JTD0-1]
XP_006715325.1. XM_006715262.2. [Q5JTD0-1]
XP_006715326.1. XM_006715263.2. [Q5JTD0-1]
XP_006715327.1. XM_006715264.2. [Q5JTD0-1]
XP_006715328.1. XM_006715265.1. [Q5JTD0-2]
XP_006715329.1. XM_006715266.1. [Q5JTD0-2]
XP_011513296.1. XM_011514994.1. [Q5JTD0-1]
XP_011513297.1. XM_011514995.1. [Q5JTD0-1]
UniGeneiHs.520145.

Genome annotation databases

EnsembliENST00000259751; ENSP00000259751; ENSG00000137221. [Q5JTD0-2]
ENST00000372444; ENSP00000361521; ENSG00000137221. [Q5JTD0-2]
ENST00000372445; ENSP00000361522; ENSG00000137221. [Q5JTD0-1]
ENST00000372449; ENSP00000361527; ENSG00000137221. [Q5JTD0-1]
ENST00000372452; ENSP00000361530; ENSG00000137221. [Q5JTD0-2]
ENST00000436109; ENSP00000407080; ENSG00000137221. [Q5JTD0-2]
ENST00000438588; ENSP00000408769; ENSG00000137221. [Q5JTD0-1]
ENST00000612912; ENSP00000484142; ENSG00000137221. [Q5JTD0-3]
GeneIDi93643.
KEGGihsa:93643.
UCSCiuc003ovc.3. human. [Q5JTD0-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK024269 mRNA. Translation: BAB14867.1.
CR749480 mRNA. Translation: CAH18308.1.
AL117398 Transcribed RNA. Translation: CAI46221.1.
AL355802 Genomic DNA. Translation: CAI42617.1.
AL355802 Genomic DNA. Translation: CAI42618.1.
AL355802 Genomic DNA. Translation: CAI42619.1.
BC046239 mRNA. Translation: AAH46239.1.
BC064401 mRNA. Translation: AAH64401.1.
CCDSiCCDS4898.1. [Q5JTD0-2]
CCDS55004.1. [Q5JTD0-1]
RefSeqiNP_001139488.1. NM_001146016.1. [Q5JTD0-1]
NP_001139489.1. NM_001146017.1. [Q5JTD0-1]
NP_001139490.1. NM_001146018.1. [Q5JTD0-2]
NP_001139491.1. NM_001146019.1. [Q5JTD0-2]
NP_001139492.1. NM_001146020.1. [Q5JTD0-2]
NP_542171.2. NM_080604.2. [Q5JTD0-2]
XP_006715312.1. XM_006715249.1. [Q5JTD0-1]
XP_006715313.1. XM_006715250.2. [Q5JTD0-1]
XP_006715314.1. XM_006715251.2. [Q5JTD0-1]
XP_006715315.1. XM_006715252.2. [Q5JTD0-1]
XP_006715316.1. XM_006715253.2. [Q5JTD0-1]
XP_006715317.1. XM_006715254.2. [Q5JTD0-1]
XP_006715319.1. XM_006715256.1. [Q5JTD0-1]
XP_006715320.1. XM_006715257.2. [Q5JTD0-1]
XP_006715321.1. XM_006715258.2. [Q5JTD0-1]
XP_006715322.1. XM_006715259.2. [Q5JTD0-1]
XP_006715323.1. XM_006715260.1. [Q5JTD0-1]
XP_006715324.1. XM_006715261.1. [Q5JTD0-1]
XP_006715325.1. XM_006715262.2. [Q5JTD0-1]
XP_006715326.1. XM_006715263.2. [Q5JTD0-1]
XP_006715327.1. XM_006715264.2. [Q5JTD0-1]
XP_006715328.1. XM_006715265.1. [Q5JTD0-2]
XP_006715329.1. XM_006715266.1. [Q5JTD0-2]
XP_011513296.1. XM_011514994.1. [Q5JTD0-1]
XP_011513297.1. XM_011514995.1. [Q5JTD0-1]
UniGeneiHs.520145.

3D structure databases

ProteinModelPortaliQ5JTD0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi125043. 19 interactions.
IntActiQ5JTD0. 14 interactions.
STRINGi9606.ENSP00000361522.

PTM databases

iPTMnetiQ5JTD0.
PhosphoSiteiQ5JTD0.

Polymorphism and mutation databases

BioMutaiTJAP1.
DMDMi74742134.

Proteomic databases

EPDiQ5JTD0.
MaxQBiQ5JTD0.
PaxDbiQ5JTD0.
PeptideAtlasiQ5JTD0.
PRIDEiQ5JTD0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000259751; ENSP00000259751; ENSG00000137221. [Q5JTD0-2]
ENST00000372444; ENSP00000361521; ENSG00000137221. [Q5JTD0-2]
ENST00000372445; ENSP00000361522; ENSG00000137221. [Q5JTD0-1]
ENST00000372449; ENSP00000361527; ENSG00000137221. [Q5JTD0-1]
ENST00000372452; ENSP00000361530; ENSG00000137221. [Q5JTD0-2]
ENST00000436109; ENSP00000407080; ENSG00000137221. [Q5JTD0-2]
ENST00000438588; ENSP00000408769; ENSG00000137221. [Q5JTD0-1]
ENST00000612912; ENSP00000484142; ENSG00000137221. [Q5JTD0-3]
GeneIDi93643.
KEGGihsa:93643.
UCSCiuc003ovc.3. human. [Q5JTD0-1]

Organism-specific databases

CTDi93643.
GeneCardsiTJAP1.
H-InvDBHIX0165025.
HGNCiHGNC:17949. TJAP1.
HPAiHPA030164.
HPA030165.
HPA030166.
MIMi612658. gene.
neXtProtiNX_Q5JTD0.
PharmGKBiPA38268.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IJKM. Eukaryota.
ENOG410Z76C. LUCA.
GeneTreeiENSGT00530000063778.
HOVERGENiHBG056279.
InParanoidiQ5JTD0.
KOiK06105.
OMAiMSEGVPG.
OrthoDBiEOG7JT6VT.
PhylomeDBiQ5JTD0.
TreeFamiTF331612.

Miscellaneous databases

ChiTaRSiTJAP1. human.
GeneWikiiTJAP1.
GenomeRNAii93643.
PROiQ5JTD0.
SOURCEiSearch...

Gene expression databases

BgeeiQ5JTD0.
CleanExiHS_TJAP1.
ExpressionAtlasiQ5JTD0. baseline and differential.
GenevisibleiQ5JTD0. HS.

Family and domain databases

InterProiIPR028179. Tjap1.
[Graphical view]
PANTHERiPTHR28664:SF3. PTHR28664:SF3. 1 hit.
PfamiPF15453. Pilt. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 4).
    Tissue: Testis and Uterus.
  3. "The DNA sequence and analysis of human chromosome 6."
    Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
    Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Tissue: Muscle and Skin.
  5. "Pilt, a novel peripheral membrane protein at tight junctions in epithelial cells."
    Kawabe H., Nakanishi H., Asada M., Fukuhara A., Morimoto K., Takeuchi M., Takai Y.
    J. Biol. Chem. 276:48350-48355(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH DLG1, TISSUE SPECIFICITY.
  6. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
    Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.
    Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  7. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Platelet.
  8. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-318; SER-320; SER-345 AND SER-545, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-300 AND SER-545, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  11. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-300; SER-491 AND SER-545, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  12. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-300; SER-491 AND SER-545, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  13. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT THR-2, CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS], IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  14. "Toward a comprehensive characterization of a human cancer cell phosphoproteome."
    Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J., Mohammed S.
    J. Proteome Res. 12:260-271(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-300; SER-345; THR-422 AND SER-545, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma and Erythroleukemia.
  15. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-300; THR-422 AND SER-491, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.

Entry informationi

Entry nameiTJAP1_HUMAN
AccessioniPrimary (citable) accession number: Q5JTD0
Secondary accession number(s): Q05BH9
, Q5JTD1, Q5JWW1, Q68DB2, Q6P2P3, Q9H7V7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: February 15, 2005
Last modified: July 6, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.