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Protein

Placenta-specific protein 9

Gene

PLAC9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Placenta-specific protein 9
Gene namesi
Name:PLAC9
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:19255. PLAC9.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134941839.

Polymorphism and mutation databases

BioMutaiPLAC9.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence analysisAdd
BLAST
Chaini23 – 9775Placenta-specific protein 9PRO_0000261405Add
BLAST

Proteomic databases

PaxDbiQ5JTB6.
PRIDEiQ5JTB6.

PTM databases

iPTMnetiQ5JTB6.

Expressioni

Gene expression databases

BgeeiQ5JTB6.
CleanExiHS_PLAC9.
ExpressionAtlasiQ5JTB6. baseline and differential.
GenevisibleiQ5JTB6. HS.

Organism-specific databases

HPAiHPA043469.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
EMILIN1Q9Y6C25EBI-3923605,EBI-744586

Protein-protein interaction databases

BioGridi128524. 4 interactions.
IntActiQ5JTB6. 4 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ5JTB6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PLAC9 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410J8HG. Eukaryota.
ENOG41118J4. LUCA.
GeneTreeiENSGT00390000017848.
HOGENOMiHOG000115572.
HOVERGENiHBG056275.
InParanoidiQ5JTB6.
OMAiVCDRHMA.
PhylomeDBiQ5JTB6.
TreeFamiTF338208.

Family and domain databases

InterProiIPR027941. PLAC9.
[Graphical view]
PfamiPF15205. PLAC9. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5JTB6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPLLCALTG LALLRAAGSL AAAEPFSPPR GDSAQSTACD RHMAVQRRLD
60 70 80 90
VMEEMVEKTV DHLGTEVKGL LGLLEELAWN LPPGPFSPAP DLLGDGF
Length:97
Mass (Da):10,309
Last modified:February 15, 2005 - v1
Checksum:i02B112554401952F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL356095 Genomic DNA. Translation: CAI40449.1.
BC066348 mRNA. Translation: AAH66348.1.
BC090922 mRNA. Translation: AAH90922.1.
BC117332 mRNA. Translation: AAI17333.1.
BC117334 mRNA. Translation: AAI17335.1.
CCDSiCCDS31232.1.
RefSeqiNP_001012991.1. NM_001012973.1.
UniGeneiHs.204947.

Genome annotation databases

EnsembliENST00000372263; ENSP00000361337; ENSG00000189129.
GeneIDi219348.
KEGGihsa:219348.
UCSCiuc001kbp.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL356095 Genomic DNA. Translation: CAI40449.1.
BC066348 mRNA. Translation: AAH66348.1.
BC090922 mRNA. Translation: AAH90922.1.
BC117332 mRNA. Translation: AAI17333.1.
BC117334 mRNA. Translation: AAI17335.1.
CCDSiCCDS31232.1.
RefSeqiNP_001012991.1. NM_001012973.1.
UniGeneiHs.204947.

3D structure databases

ProteinModelPortaliQ5JTB6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi128524. 4 interactions.
IntActiQ5JTB6. 4 interactions.

PTM databases

iPTMnetiQ5JTB6.

Polymorphism and mutation databases

BioMutaiPLAC9.

Proteomic databases

PaxDbiQ5JTB6.
PRIDEiQ5JTB6.

Protocols and materials databases

DNASUi219348.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000372263; ENSP00000361337; ENSG00000189129.
GeneIDi219348.
KEGGihsa:219348.
UCSCiuc001kbp.2. human.

Organism-specific databases

CTDi219348.
GeneCardsiPLAC9.
HGNCiHGNC:19255. PLAC9.
HPAiHPA043469.
MIMi612857. gene.
neXtProtiNX_Q5JTB6.
PharmGKBiPA134941839.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J8HG. Eukaryota.
ENOG41118J4. LUCA.
GeneTreeiENSGT00390000017848.
HOGENOMiHOG000115572.
HOVERGENiHBG056275.
InParanoidiQ5JTB6.
OMAiVCDRHMA.
PhylomeDBiQ5JTB6.
TreeFamiTF338208.

Miscellaneous databases

GenomeRNAii219348.
PROiQ5JTB6.
SOURCEiSearch...

Gene expression databases

BgeeiQ5JTB6.
CleanExiHS_PLAC9.
ExpressionAtlasiQ5JTB6. baseline and differential.
GenevisibleiQ5JTB6. HS.

Family and domain databases

InterProiIPR027941. PLAC9.
[Graphical view]
PfamiPF15205. PLAC9. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The DNA sequence and comparative analysis of human chromosome 10."
    Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
    , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
    Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Placenta and Testis.

Entry informationi

Entry nameiPLAC9_HUMAN
AccessioniPrimary (citable) accession number: Q5JTB6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: February 15, 2005
Last modified: June 8, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.