SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5JSL3

- DOC11_HUMAN

UniProt

Q5JSL3 - DOC11_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Dedicator of cytokinesis protein 11
Gene
DOCK11, ZIZ2
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP By similarity.

GO - Molecular functioni

  1. Rho guanyl-nucleotide exchange factor activity Source: Ensembl
Complete GO annotation...

GO - Biological processi

  1. blood coagulation Source: Reactome
  2. small GTPase mediated signal transduction Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Guanine-nucleotide releasing factor

Enzyme and pathway databases

ReactomeiREACT_24970. Factors involved in megakaryocyte development and platelet production.

Names & Taxonomyi

Protein namesi
Recommended name:
Dedicator of cytokinesis protein 11
Alternative name(s):
Activated Cdc42-associated guanine nucleotide exchange factor
Short name:
ACG
Zizimin-2
Gene namesi
Name:DOCK11
Synonyms:ZIZ2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X

Organism-specific databases

HGNCiHGNC:23483. DOCK11.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: Reactome
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA128394757.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 20732073Dedicator of cytokinesis protein 11
PRO_0000299558Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei161 – 1611Phosphoserine1 Publication
Modified residuei248 – 2481Phosphotyrosine1 Publication
Modified residuei251 – 2511Phosphotyrosine1 Publication
Modified residuei266 – 2661Phosphothreonine1 Publication
Modified residuei440 – 4401Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ5JSL3.
PaxDbiQ5JSL3.
PRIDEiQ5JSL3.

PTM databases

PhosphoSiteiQ5JSL3.

Expressioni

Gene expression databases

ArrayExpressiQ5JSL3.
BgeeiQ5JSL3.
CleanExiHS_DOCK11.
GenevestigatoriQ5JSL3.

Organism-specific databases

HPAiHPA059695.

Interactioni

Subunit structurei

Interacts with CDC42 By similarity.

Protein-protein interaction databases

BioGridi126589. 3 interactions.
IntActiQ5JSL3. 4 interactions.
STRINGi9606.ENSP00000276202.

Structurei

3D structure databases

ProteinModelPortaliQ5JSL3.
SMRiQ5JSL3. Positions 162-294, 1613-2035.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini165 – 272108PH
Add
BLAST
Domaini640 – 818179DHR-1
Add
BLAST
Domaini1609 – 2036428DHR-2
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni66 – 12661Interaction with activated CDC42 By similarity
Add
BLAST

Domaini

The DHR-2 domain is necessary for the GEF activity By similarity.

Sequence similaritiesi

Belongs to the DOCK family.
Contains 1 DHR-1 domain.
Contains 1 DHR-2 domain.
Contains 1 PH domain.

Phylogenomic databases

eggNOGiNOG242127.
HOGENOMiHOG000231373.
HOVERGENiHBG107819.
PhylomeDBiQ5JSL3.
TreeFamiTF313629.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR016024. ARM-type_fold.
IPR027007. DHR-1_domain.
IPR027357. DHR-2.
IPR026791. DOCK.
IPR010703. DOCK_C.
IPR021816. DOCK_C/D_N.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
[Graphical view]
PANTHERiPTHR23317. PTHR23317. 1 hit.
PfamiPF06920. Ded_cyto. 1 hit.
PF14429. DOCK-C2. 1 hit.
PF11878. DUF3398. 1 hit.
PF00169. PH. 1 hit.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 4 hits.
PROSITEiPS51650. DHR_1. 1 hit.
PS51651. DHR_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5JSL3-1 [UniParc]FASTAAdd to Basket

« Hide

MAEVRKFTKR LSKPGTAAEL RQSVSEAVRG SVVLEKAKVV EPLDYENVIA     50
QRKTQIYSDP LRDLLMFPME DISISVIGRQ RRTVQSTVPE DAEKRAQSLF 100
VKECIKTYST DWHVVNYKYE DFSGDFRMLP CKSLRPEKIP NHVFEIDEDC 150
EKDEDSSSLC SQKGGVIKQG WLHKANVNST ITVTMKVFKR RYFYLTQLPD 200
GSYILNSYKD EKNSKESKGC IYLDACIDVV QCPKMRRHAF ELKMLDKYSH 250
YLAAETEQEM EEWLITLKKI IQINTDSLVQ EKKETVETAQ DDETSSQGKA 300
ENIMASLERS MHPELMKYGR ETEQLNKLSR GDGRQNLFSF DSEVQRLDFS 350
GIEPDIKPFE EKCNKRFLVN CHDLTFNILG QIGDNAKGPP TNVEPFFINL 400
ALFDVKNNCK ISADFHVDLN PPSVREMLWG SSTQLASDGS PKGSSPESYI 450
HGIAESQLRY IQQGIFSVTN PHPEIFLVAR IEKVLQGNIT HCAEPYIKNS 500
DPVKTAQKVH RTAKQVCSRL GQYRMPFAWA ARPIFKDTQG SLDLDGRFSP 550
LYKQDSSKLS SEDILKLLSE YKKPEKTKLQ IIPGQLNITV ECVPVDLSNC 600
ITSSYVPLKP FEKNCQNITV EVEEFVPEMT KYCYPFTIYK NHLYVYPLQL 650
KYDSQKTFAK ARNIAVCVEF RDSDESDASA LKCIYGKPAG SVFTTNAYAV 700
VSHHNQNPEF YDEIKIELPI HLHQKHHLLF TFYHVSCEIN TKGTTKKQDT 750
VETPVGFAWV PLLKDGRIIT FEQQLPVSAN LPPGYLNLND AESRRQCNVD 800
IKWVDGAKPL LKIKSHLEST IYTQDLHVHK FFHHCQLIQS GSKEVPGELI 850
KYLKCLHAME IQVMIQFLPV ILMQLFRVLT NMTHEDDVPI NCTMVLLHIV 900
SKCHEEGLDS YLRSFIKYSF RPEKPSAPQA QLIHETLATT MIAILKQSAD 950
FLSINKLLKY SWFFFEIIAK SMATYLLEEN KIKLPRGQRF PETYHHVLHS 1000
LLLAIIPHVT IRYAEIPDES RNVNYSLASF LKRCLTLMDR GFIFNLINDY 1050
ISGFSPKDPK VLAEYKFEFL QTICNHEHYI PLNLPMAFAK PKLQRVQDSN 1100
LEYSLSDEYC KHHFLVGLLL RETSIALQDN YEIRYTAISV IKNLLIKHAF 1150
DTRYQHKNQQ AKIAQLYLPF VGLLLENIQR LAGRDTLYSC AAMPNSASRD 1200
EFPCGFTSPA NRGSLSTDKD TAYGSFQNGH GIKREDSRGS LIPEGATGFP 1250
DQGNTGENTR QSSTRSSVSQ YNRLDQYEIR SLLMCYLYIV KMISEDTLLT 1300
YWNKVSPQEL INILILLEVC LFHFRYMGKR NIARVHDAWL SKHFGIDRKS 1350
QTMPALRNRS GVMQARLQHL SSLESSFTLN HSSTTTEADI FHQALLEGNT 1400
ATEVSLTVLD TISFFTQCFK TQLLNNDGHN PLMKKVFDIH LAFLKNGQSE 1450
VSLKHVFASL RAFISKFPSA FFKGRVNMCA AFCYEVLKCC TSKISSTRNE 1500
ASALLYLLMR NNFEYTKRKT FLRTHLQIII AVSQLIADVA LSGGSRFQES 1550
LFIINNFANS DRPMKATAFP AEVKDLTKRI RTVLMATAQM KEHEKDPEML 1600
IDLQYSLAKS YASTPELRKT WLDSMAKIHV KNGDFSEAAM CYVHVAALVA 1650
EFLHRKKLFP NGCSAFKKIT PNIDEEGAMK EDAGMMDVHY SEEVLLELLE 1700
QCVDGLWKAE RYEIISEISK LIVPIYEKRR EFEKLTQVYR TLHGAYTKIL 1750
EVMHTKKRLL GTFFRVAFYG QSFFEEEDGK EYIYKEPKLT GLSEISLRLV 1800
KLYGEKFGTE NVKIIQDSDK VNAKELDPKY AHIQVTYVKP YFDDKELTER 1850
KTEFERNHNI SRFVFEAPYT LSGKKQGCIE EQCKRRTILT TSNSFPYVKK 1900
RIPINCEQQI NLKPIDVATD EIKDKTAELQ KLCSSTDVDM IQLQLKLQGC 1950
VSVQVNAGPL AYARAFLNDS QASKYPPKKV SELKDMFRKF IQACSIALEL 2000
NERLIKEDQV EYHEGLKSNF RDMVKELSDI IHEQILQEDT MHSPWMSNTL 2050
HVFCAISGTS SDRGYGSPRY AEV 2073
Length:2,073
Mass (Da):237,671
Last modified:September 11, 2007 - v2
Checksum:i558FC01EE5D23B6E
GO

Sequence cautioni

The sequence BAB71253.1 differs from that shown. Reason: Erroneous initiation.
The sequence BAC86230.1 differs from that shown. Reason: Erroneous initiation.
The sequence CAI41407.1 differs from that shown. Reason: Erroneous gene model prediction.
The sequence CAI41411.1 differs from that shown. Reason: Erroneous gene model prediction.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti813 – 8131I → F.
Corresponds to variant rs16995229 [ dbSNP | Ensembl ].
VAR_034854

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti376 – 3761F → L in AAU04438. 1 Publication
Sequence conflicti740 – 7401N → K in AAU04438. 1 Publication
Sequence conflicti1984 – 19841K → E in AAU04438. 1 Publication
Sequence conflicti1984 – 19841K → E in BAB71253. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY692226 mRNA. Translation: AAU04438.1.
AL391237, AC007021, AL391280 Genomic DNA. Translation: CAI41407.1. Sequence problems.
AL391280, AC007021, AL391237 Genomic DNA. Translation: CAI41411.1. Sequence problems.
CH471161 Genomic DNA. Translation: EAW89895.1.
AK056684 mRNA. Translation: BAB71253.1. Different initiation.
AK125641 mRNA. Translation: BAC86230.1. Different initiation.
BC047713 mRNA. Translation: AAH47713.1.
CCDSiCCDS35373.1.
RefSeqiNP_653259.3. NM_144658.3.
UniGeneiHs.368203.

Genome annotation databases

EnsembliENST00000276202; ENSP00000276202; ENSG00000147251.
GeneIDi139818.
KEGGihsa:139818.
UCSCiuc004eqp.2. human.

Polymorphism databases

DMDMi158563857.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY692226 mRNA. Translation: AAU04438.1 .
AL391237 , AC007021 , AL391280 Genomic DNA. Translation: CAI41407.1 . Sequence problems.
AL391280 , AC007021 , AL391237 Genomic DNA. Translation: CAI41411.1 . Sequence problems.
CH471161 Genomic DNA. Translation: EAW89895.1 .
AK056684 mRNA. Translation: BAB71253.1 . Different initiation.
AK125641 mRNA. Translation: BAC86230.1 . Different initiation.
BC047713 mRNA. Translation: AAH47713.1 .
CCDSi CCDS35373.1.
RefSeqi NP_653259.3. NM_144658.3.
UniGenei Hs.368203.

3D structure databases

ProteinModelPortali Q5JSL3.
SMRi Q5JSL3. Positions 162-294, 1613-2035.
ModBasei Search...

Protein-protein interaction databases

BioGridi 126589. 3 interactions.
IntActi Q5JSL3. 4 interactions.
STRINGi 9606.ENSP00000276202.

PTM databases

PhosphoSitei Q5JSL3.

Polymorphism databases

DMDMi 158563857.

Proteomic databases

MaxQBi Q5JSL3.
PaxDbi Q5JSL3.
PRIDEi Q5JSL3.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000276202 ; ENSP00000276202 ; ENSG00000147251 .
GeneIDi 139818.
KEGGi hsa:139818.
UCSCi uc004eqp.2. human.

Organism-specific databases

CTDi 139818.
GeneCardsi GC0XP117629.
H-InvDB HIX0017007.
HGNCi HGNC:23483. DOCK11.
HPAi HPA059695.
MIMi 300681. gene.
neXtProti NX_Q5JSL3.
PharmGKBi PA128394757.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG242127.
HOGENOMi HOG000231373.
HOVERGENi HBG107819.
PhylomeDBi Q5JSL3.
TreeFami TF313629.

Enzyme and pathway databases

Reactomei REACT_24970. Factors involved in megakaryocyte development and platelet production.

Miscellaneous databases

ChiTaRSi DOCK11. human.
GeneWikii Dock11.
GenomeRNAii 139818.
NextBioi 84048.
PROi Q5JSL3.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q5JSL3.
Bgeei Q5JSL3.
CleanExi HS_DOCK11.
Genevestigatori Q5JSL3.

Family and domain databases

Gene3Di 2.30.29.30. 1 hit.
InterProi IPR016024. ARM-type_fold.
IPR027007. DHR-1_domain.
IPR027357. DHR-2.
IPR026791. DOCK.
IPR010703. DOCK_C.
IPR021816. DOCK_C/D_N.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
[Graphical view ]
PANTHERi PTHR23317. PTHR23317. 1 hit.
Pfami PF06920. Ded_cyto. 1 hit.
PF14429. DOCK-C2. 1 hit.
PF11878. DUF3398. 1 hit.
PF00169. PH. 1 hit.
[Graphical view ]
SMARTi SM00233. PH. 1 hit.
[Graphical view ]
SUPFAMi SSF48371. SSF48371. 4 hits.
PROSITEi PS51650. DHR_1. 1 hit.
PS51651. DHR_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of a DOCK180-related guanine nucleotide exchange factor that is capable of mediating a positive feedback activation of Cdc42."
    Lin Q., Yang W., Baird D., Feng Q., Cerione R.A.
    J. Biol. Chem. 281:35253-35262(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Brain.
  2. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 811-2073.
    Tissue: Synovium.
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1283-2073.
    Tissue: Testis.
  6. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-161, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic kidney.
  7. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-248; TYR-251; THR-266 AND SER-440, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
    Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
    Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  9. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiDOC11_HUMAN
AccessioniPrimary (citable) accession number: Q5JSL3
Secondary accession number(s): A6NMF0
, Q66M66, Q6ZUJ5, Q86VU8, Q96MN3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: September 11, 2007
Last modified: September 3, 2014
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Miscellaneous

'Zizim' means 'spike' in Hebrew.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi