TFDP1

Functionⁱ

GO - Molecular functionⁱ

DNA binding Source: UniProtKB-KW
DNA binding transcription factor activity Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cell cycle Source: InterPro
transcription, DNA-templated Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-bindingUniRule annotation
Biological process	Transcription, Transcription regulationUniRule annotation

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Transcription factor Dp-1Imported
Gene namesⁱ	Name:TFDP1Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 13

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000198176.12.
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:11749. TFDP1.

Keywords - Cellular componentⁱ

NucleusUniRule annotation

Pathology & Biotechⁱ

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000198176.

OpenTargetsⁱ

ENSG00000198176.

PTM / Processingⁱ

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	Q5JSB5.
PRIDEⁱ	Q5JSB5.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000198176.
ExpressionAtlasⁱ	Q5JSB5. baseline and differential.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	111 – 193	E2F_TDPInterPro annotationAdd BLAST		83

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	202 – 222	Sequence analysisAdd BLAST		21

Sequence similaritiesⁱ

Belongs to the E2F/DP family.UniRule annotation

Keywords - Domainⁱ

Coiled coilSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG2829. Eukaryota. ENOG410Y9QP. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000018222.
HOGENOMⁱ	HOG000030696.
HOVERGENⁱ	HBG009894.

Family and domain databases

Gene3Dⁱ	1.10.10.10. 1 hit. 1.20.140.80. 1 hit.
InterProⁱ	View protein in InterPro IPR028313. DP-1. IPR037241. E2F-DP_heterodim. IPR003316. E2F_WHTH_DNA-bd_dom. IPR038168. TF_DP_C_sf. IPR014889. Transc_factor_DP_C. IPR015648. Transcrpt_fac_DP. IPR036388. WH-like_DNA-bd_sf. IPR036390. WH_DNA-bd_sf.
PANTHERⁱ	PTHR12548. PTHR12548. 1 hit. PTHR12548:SF4. PTHR12548:SF4. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF08781. DP. 1 hit. PF02319. E2F_TDP. 1 hit.
PIRSFⁱ	PIRSF009404. Transcription_factor_DP. 1 hit.
SMARTⁱ	View protein in SMART SM01372. E2F_TDP. 1 hit.
SUPFAMⁱ	SSF144074. SSF144074. 1 hit. SSF46785. SSF46785. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Fragment.

Q5JSB5-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAKDAGLIEA NGELKVFIDQ NLSPGKGVVS LVAVHPSTVN PLGKQLLPKT 
        60         70         80         90        100
FGQSNVNIAQ QVVIGTPQRP AASNTLVVGS PHTPSTHFAS QNQPSDSSPW 
       110        120        130        140        150
SAGKRNRKGE KNGKGLRHFS MKVCEKVQRK GTTSYNEVAD ELVAEFSAAD 
       160        170        180        190        200
NHILPNESAY DQKNIRRRVY DALNVLMAMN IISKEKKEIK WIGLPTNSAQ 
       210        220        230 
ECQNLEVERQ RRLERIKQKQ SQLQELILQQ IAFKN

Length:235

Mass (Da):26,062

Last modified:October 5, 2016 - v8

Checksum:ⁱ738BAD9D389A9881

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	235	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL442125 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AL442125 Genomic DNA. No translation available.

Genome annotation databases

Ensemblⁱ	ENST00000408980; ENSP00000386145; ENSG00000198176.
UCSC genome browser More...UCSCⁱ	uc058yob.1. human.

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q5JSB5	UPI0007DC7C83 UPI0005CFF4D2 Q5JSB6 A0A2J8X7R5 A0A2J8KSY4	Homo sapiens (Human) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Pan troglodytes (Chimpanzee)	235	UniRef100_Q5JSB5	Cluster: Transcription factor Dp-1 (Fragment)	6

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q5JSB5	UPI0007DC7C83 UPI0005CFF4D2 Q5JSB6 A0A2J8X7R5 A0A2J8KSY4 UPI0002065747 B7Z569	Homo sapiens (Human) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Pan troglodytes (Chimpanzee)	235	UniRef90_Q5JSB5	Cluster: Transcription factor Dp-1 (Fragment)	8

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q5JSB5	UPI0007DC7C83 UPI0005CFF4D2 Q5JSB6 A0A2J8X7R5 A0A2J8KSY4 UPI0002065747 B7Z569 UPI0006444BED UPI00099FEA51 UPI00099FB7C9 +48	Homo sapiens (Human) Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) Pan troglodytes (Chimpanzee) Clupea harengus (Atlantic herring) Oncorhynchus kisutch (Coho salmon) (Salmo kisutch) Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) Salmo salar (Atlantic salmon) Salvelinus alpinus (Arctic char) (Salmo alpinus) Boleophthalmus pectinirostris (Great blue-spotted mudskipper) (Gobius pectinirostris) Monopterus albus (Swamp eel) And more	235	UniRef50_Q5JSB5	Cluster: Transcription factor Dp-1 (Fragment)	59

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AL442125 Genomic DNA. No translation available.

Select the link destinations:
EMBLⁱ
GenBankⁱ
DDBJⁱ

Links Updated

AL442125 Genomic DNA. No translation available.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	Q5JSB5.
PRIDEⁱ	Q5JSB5.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000408980; ENSP00000386145; ENSG00000198176.
UCSC genome browser More...UCSCⁱ	uc058yob.1. human.

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000198176.12.
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:11749. TFDP1.
Open Targets More...OpenTargetsⁱ	ENSG00000198176.
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG2829. Eukaryota. ENOG410Y9QP. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000018222.
HOGENOMⁱ	HOG000030696.
HOVERGENⁱ	HBG009894.

Miscellaneous databases

ChiTaRSⁱ	TFDP1. human.

ChiTaRSⁱ

TFDP1. human.

Gene expression databases

Bgeeⁱ	ENSG00000198176.
ExpressionAtlasⁱ	Q5JSB5. baseline and differential.

Family and domain databases

Gene3Dⁱ	1.10.10.10. 1 hit. 1.20.140.80. 1 hit.
InterProⁱ	View protein in InterPro IPR028313. DP-1. IPR037241. E2F-DP_heterodim. IPR003316. E2F_WHTH_DNA-bd_dom. IPR038168. TF_DP_C_sf. IPR014889. Transc_factor_DP_C. IPR015648. Transcrpt_fac_DP. IPR036388. WH-like_DNA-bd_sf. IPR036390. WH_DNA-bd_sf.
PANTHERⁱ	PTHR12548. PTHR12548. 1 hit. PTHR12548:SF4. PTHR12548:SF4. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF08781. DP. 1 hit. PF02319. E2F_TDP. 1 hit.
PIRSFⁱ	PIRSF009404. Transcription_factor_DP. 1 hit.
SMARTⁱ	View protein in SMART SM01372. E2F_TDP. 1 hit.
SUPFAMⁱ	SSF144074. SSF144074. 1 hit. SSF46785. SSF46785. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q5JSB5_HUMAN
Accessionⁱ	Q5JSB5Primary (citable) accession number: Q5JSB5
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	February 15, 2005
	Last sequence update:	October 5, 2016
	Last modified:	March 28, 2018
	This is version 116 of the entry and version 8 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q5JSB5 (Q5JSB5_HUMAN)

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Transcription factor Dp-1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Other locations

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ