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Protein
Submitted name:

Pre-B-cell leukemia transcription factor 3

Gene

PBX3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionDNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Pre-B-cell leukemia transcription factor 3Imported
Gene namesi
Name:PBX3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

HGNCiHGNC:8634. PBX3.

Subcellular locationi

  • Nucleus SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000167081.

PTM / Processingi

Proteomic databases

EPDiQ5JS98.
MaxQBiQ5JS98.
PaxDbiQ5JS98.
PeptideAtlasiQ5JS98.
PRIDEiQ5JS98.

Expressioni

Gene expression databases

BgeeiENSG00000167081.
ExpressionAtlasiQ5JS98. baseline and differential.

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

IntActiQ5JS98. 34 interactors.

Structurei

3D structure databases

ProteinModelPortaliQ5JS98.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini233 – 317Homeobox DNA-bindingInterPro annotationAdd BLAST85

Keywords - Domaini

HomeoboxSAAS annotation

Phylogenomic databases

eggNOGiKOG0774. Eukaryota.
ENOG410XRVF. LUCA.
GeneTreeiENSGT00390000016426.
HOGENOMiHOG000266972.
HOVERGENiHBG000122.
OMAiSMQSLNG.
OrthoDBiEOG091G10TD.
PhylomeDBiQ5JS98.

Family and domain databases

InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR001356. Homeobox_dom.
IPR008422. Homeobox_KN_domain.
IPR005542. PBX.
PfamiView protein in Pfam
PF05920. Homeobox_KN. 1 hit.
PF03792. PBC. 1 hit.
SMARTiView protein in SMART
SM00389. HOX. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS50071. HOMEOBOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5JS98-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDQSRMLQT LAGVNLAGHS VQGGMALPPP PHGHEGADGD GRKQDIGDIL
60 70 80 90 100
HQIMTITDQS LDEAQAKKHA LNCHRMKPAL FSVLCEIKEK TGLSIRGAQE
110 120 130 140 150
EDPPDPQLMR LDNMLLAEGV SGPEKGGGSA AAAAAAAASG GSSDNSIEHS
160 170 180 190 200
DYRAKLTQIR QIYHTELEKY EQACNEFTTH VMNLLREQSR TRPISPKEIE
210 220 230 240 250
RMVGIIHRKF SSIQMQLKQS TCEAVMILRS RFLDARRKRR NFSKQATEIL
260 270 280 290 300
NEYFYSHLSN PYPSEEAKEE LAKKCSITVS QSLVKDPKER GSKGSDIQPT
310 320 330 340 350
SVVSNWFGNK RIRYKKNIGK FQEEANLYAA KTAVTAAHAV AAAVQNNQTN
360 370 380 390 400
SPTTPNSGSS GSFNLPNSGD MFMNMQSLNG DSYQGSQVGA NVQSQVDTLR
410 420 430 440 450
HVINQTGGYS DGLGGNSLYS PHNLNANGGW QDATTPSSVT SPTEGPGSVH

SDTSN
Length:455
Mass (Da):49,400
Last modified:February 5, 2008 - v1
Checksum:i57AFE907121F6FD2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL358074 Genomic DNA. No translation available.
AL445186 Genomic DNA. No translation available.
AL627303 Genomic DNA. No translation available.
KF458944 Genomic DNA. No translation available.
RefSeqiXP_006717193.1. XM_006717130.1.
UniGeneiHs.428027.

Genome annotation databases

EnsembliENST00000373487; ENSP00000362586; ENSG00000167081.
GeneIDi5090.
UCSCiuc004bqe.4. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ5JS98_HUMAN
AccessioniPrimary (citable) accession number: Q5JS98
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: July 5, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported