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Protein
Submitted name:

Peripheral plasma membrane protein CASK

Gene

CASK

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Peripheral plasma membrane protein CASKImported
Gene namesi
Name:CASKImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000147044.20.
HGNCiHGNC:1497. CASK.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000147044.

PTM / Processingi

Proteomic databases

MaxQBiQ5JS79.
PaxDbiQ5JS79.
PeptideAtlasiQ5JS79.
PRIDEiQ5JS79.

Expressioni

Gene expression databases

BgeeiENSG00000147044.
ExpressionAtlasiQ5JS79. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ5JS79.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini67 – 137SH3InterPro annotationAdd BLAST71
Domaini194 – 366Guanylate kinase-likeInterPro annotationAdd BLAST173

Keywords - Domaini

SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0033. Eukaryota.
KOG0609. Eukaryota.
COG0194. LUCA.
GeneTreeiENSGT00760000118866.
HOGENOMiHOG000233034.

Family and domain databases

InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
IPR036034. PDZ_sf.
IPR036028. SH3-like_dom_sf.
IPR001452. SH3_domain.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
PF07653. SH3_2. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SM00326. SH3. 1 hit.
SUPFAMiSSF50044. SSF50044. 2 hits.
SSF50156. SSF50156. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
PS50002. SH3. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q5JS79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DEIREINGIS VANQTVEQLQ KMLREMRGSI TFKIVPSYRT QSSSCERDSP
60 70 80 90 100
STSRQSPANG HSSTNNSVSI YVRAQFEYDP AKDDLIPCKE AGIRFRVGDI
110 120 130 140 150
IQIISKDDHN WWQGKLENSK NGTAGLIPSP ELQEWRVACI AMEKTKQEQQ
160 170 180 190 200
ASCTWFGKKK KQYKDKYLAK HNAVFDQLDL VTYEEVVKLP AFKRKTLVLL
210 220 230 240 250
GAHGVGRRHI KNTLITKHPD RFAYPIPHTT RPPKKDEENG KNYYFVSHDQ
260 270 280 290 300
MMQDISNNEY LEYGSHEDAM YGTKLETIRK IHEQGLIAIL DVEPQALKVL
310 320 330 340 350
RTAEFAPFVV FIAAPTITPG LNEDESLQRL QKESDILQRT YAHYFDLTII
360 370 380
NNEIDETIRH LEEAVELVCT APQWVPVSWV Y
Length:381
Mass (Da):43,742
Last modified:February 15, 2005 - v1
Checksum:iE68D4BBC1B5435C0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL158144 Genomic DNA. No translation available.
AL353691 Genomic DNA. No translation available.
AL445239 Genomic DNA. No translation available.
AL603754 Genomic DNA. No translation available.
AL627402 Genomic DNA. No translation available.
KF459071 Genomic DNA. No translation available.
KF459072 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000378168; ENSP00000367410; ENSG00000147044.
UCSCiuc064yqr.1. human.

Similar proteinsi

Entry informationi

Entry nameiQ5JS79_HUMAN
AccessioniPrimary (citable) accession number: Q5JS79
Secondary accession number(s): A6NFC6
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: November 22, 2017
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported