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Protein
Submitted name:

Peripheral plasma membrane protein CASK

Gene

CASK

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Peripheral plasma membrane protein CASKImported
Gene namesi
Name:CASKImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000147044.20
HGNCiHGNC:1497 CASK

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000147044

PTM / Processingi

Proteomic databases

MaxQBiQ5JS79
PeptideAtlasiQ5JS79
PRIDEiQ5JS79

Expressioni

Gene expression databases

BgeeiENSG00000147044
ExpressionAtlasiQ5JS79 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5JS79
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini67 – 137SH3InterPro annotationAdd BLAST71
Domaini194 – 366Guanylate kinase-likeInterPro annotationAdd BLAST173

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili9 – 29Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0033 Eukaryota
KOG0609 Eukaryota
COG0194 LUCA
GeneTreeiENSGT00760000118866
HOGENOMiHOG000233034

Family and domain databases

InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
IPR036034 PDZ_sf
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
PF07653 SH3_2, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF50044 SSF50044, 2 hits
SSF50156 SSF50156, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Fragment.

Q5JS79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
DEIREINGIS VANQTVEQLQ KMLREMRGSI TFKIVPSYRT QSSSCERDSP
60 70 80 90 100
STSRQSPANG HSSTNNSVSI YVRAQFEYDP AKDDLIPCKE AGIRFRVGDI
110 120 130 140 150
IQIISKDDHN WWQGKLENSK NGTAGLIPSP ELQEWRVACI AMEKTKQEQQ
160 170 180 190 200
ASCTWFGKKK KQYKDKYLAK HNAVFDQLDL VTYEEVVKLP AFKRKTLVLL
210 220 230 240 250
GAHGVGRRHI KNTLITKHPD RFAYPIPHTT RPPKKDEENG KNYYFVSHDQ
260 270 280 290 300
MMQDISNNEY LEYGSHEDAM YGTKLETIRK IHEQGLIAIL DVEPQALKVL
310 320 330 340 350
RTAEFAPFVV FIAAPTITPG LNEDESLQRL QKESDILQRT YAHYFDLTII
360 370 380
NNEIDETIRH LEEAVELVCT APQWVPVSWV Y
Length:381
Mass (Da):43,742
Last modified:February 15, 2005 - v1
Checksum:iE68D4BBC1B5435C0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL158144 Genomic DNA No translation available.
AL353691 Genomic DNA No translation available.
AL445239 Genomic DNA No translation available.
AL603754 Genomic DNA No translation available.
AL627402 Genomic DNA No translation available.
KF459071 Genomic DNA No translation available.
KF459072 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000378168; ENSP00000367410; ENSG00000147044
UCSCiuc064yqr.1 human

Similar proteinsi

Entry informationi

Entry nameiQ5JS79_HUMAN
AccessioniPrimary (citable) accession number: Q5JS79
Secondary accession number(s): A6NFC6
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: May 23, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health