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Protein
Submitted name:

Ubiquitin-like modifier-activating enzyme 1

Gene

UBA1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitin-like modifier-activating enzyme 1Imported
Gene namesi
Name:UBA1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

HGNCiHGNC:12469. UBA1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000130985.

PTM / Processingi

Proteomic databases

MaxQBiQ5JRS3.
PaxDbiQ5JRS3.
PeptideAtlasiQ5JRS3.
PRIDEiQ5JRS3.

Expressioni

Gene expression databases

BgeeiENSG00000130985.
ExpressionAtlasiQ5JRS3. baseline and differential.

Interactioni

Protein-protein interaction databases

MINTiMINT-1376624.
STRINGi9606.ENSP00000338413.

Structurei

3D structure databases

ProteinModelPortaliQ5JRS3.
SMRiQ5JRS3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini106 – 195ThiFInterPro annotationAdd BLAST90

Phylogenomic databases

eggNOGiKOG2012. Eukaryota.
COG0476. LUCA.
GeneTreeiENSGT00390000016689.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR000594. ThiF_NAD_FAD-bd.
[Graphical view]
PfamiPF00899. ThiF. 1 hit.
[Graphical view]
SUPFAMiSSF69572. SSF69572. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q5JRS3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKPHFPPAL PAPAAIPGIK GEENGCLLLP TYSVPGSMLC VIYHLDNPVG
60 70 80 90 100
KMSSSPLSKK RRVSGPDPKP GSNCSPAQSV LSEVPSVPTN GMAKNGSEAD
110 120 130 140 150
IDEGLYSRQL YVLGHEAMKR LQTSSVLVSG LRGLGVEIAK NIILGGVKAV
160 170 180 190
TLHDQGTAQW ADLSSQFYLR EEDIGKNRAE VSQPRLAELN SYVPV
Length:195
Mass (Da):20,746
Last modified:February 15, 2005 - v1
Checksum:i4A6A3032862A4200
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei195Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL513366 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000457753; ENSP00000404796; ENSG00000130985.
UCSCiuc064yua.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL513366 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliQ5JRS3.
SMRiQ5JRS3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1376624.
STRINGi9606.ENSP00000338413.

Proteomic databases

MaxQBiQ5JRS3.
PaxDbiQ5JRS3.
PeptideAtlasiQ5JRS3.
PRIDEiQ5JRS3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000457753; ENSP00000404796; ENSG00000130985.
UCSCiuc064yua.1. human.

Organism-specific databases

HGNCiHGNC:12469. UBA1.
OpenTargetsiENSG00000130985.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2012. Eukaryota.
COG0476. LUCA.
GeneTreeiENSGT00390000016689.

Miscellaneous databases

ChiTaRSiUBA1. human.

Gene expression databases

BgeeiENSG00000130985.
ExpressionAtlasiQ5JRS3. baseline and differential.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR000594. ThiF_NAD_FAD-bd.
[Graphical view]
PfamiPF00899. ThiF. 1 hit.
[Graphical view]
SUPFAMiSSF69572. SSF69572. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5JRS3_HUMAN
AccessioniPrimary (citable) accession number: Q5JRS3
Entry historyi
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: November 30, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.