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Protein
Submitted name:

Ubiquitin-like modifier-activating enzyme 1

Gene

UBA1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Ubiquitin-like modifier-activating enzyme 1Imported
Gene namesi
Name:UBA1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000130985.16
HGNCiHGNC:12469 UBA1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000130985

PTM / Processingi

Proteomic databases

EPDiQ5JRS0
MaxQBiQ5JRS0
PeptideAtlasiQ5JRS0
PRIDEiQ5JRS0

Expressioni

Gene expression databases

BgeeiENSG00000130985
ExpressionAtlasiQ5JRS0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5JRS0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini69 – 239ThiFInterPro annotationAdd BLAST171
Domaini241 – 284E1_FCCHInterPro annotationAdd BLAST44

Phylogenomic databases

eggNOGiKOG2012 Eukaryota
COG0476 LUCA
GeneTreeiENSGT00390000016689
HOGENOMiHOG000202122

Family and domain databases

InterProiView protein in InterPro
IPR032418 E1_FCCH
IPR000594 ThiF_NAD_FAD-bd
IPR035985 Ubiquitin-activating_enz
IPR000011 UBQ/SUMO-activ_enz_E1-like
PfamiView protein in Pfam
PF16190 E1_FCCH, 1 hit
PF00899 ThiF, 1 hit
PRINTSiPR01849 UBIQUITINACT
SUPFAMiSSF69572 SSF69572, 1 hit

Sequencei

Sequence statusi: Fragment.

Q5JRS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLCVIYHLDN PVGKMSSSPL SKKRRVSGPD PKPGSNCSPA QSVLSEVPSV
60 70 80 90 100
PTNGMAKNGS EADIDEGLYS RQLYVLGHEA MKRLQTSSVL VSGLRGLGVE
110 120 130 140 150
IAKNIILGGV KAVTLHDQGT AQWADLSSQF YLREEDIGKN RAEVSQPRLA
160 170 180 190 200
ELNSYVPVTA YTGPLVEDFL SGFQVVVLTN TPLEDQLRVG EFCHNRGIKL
210 220 230 240 250
VVADTRGLFG QLFCDFGEEM ILTDSNGEQP LSAMVSMVTK DNPGVVTCLD
260 270 280
EARHGFESGD FVSFSEVQGM VELNGNQPME IKVL
Length:284
Mass (Da):30,764
Last modified:February 15, 2005 - v1
Checksum:iD941D1D79E6E4AAF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei284Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL513366 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000442035; ENSP00000389583; ENSG00000130985
UCSCiuc064ytz.1 human

Similar proteinsi

Entry informationi

Entry nameiQ5JRS0_HUMAN
AccessioniPrimary (citable) accession number: Q5JRS0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: June 20, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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