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Protein

Uncharacterized protein CXorf66

Gene

CXorf66

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein CXorf66
Gene namesi
Name:CXorf66
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000203933.2
HGNCiHGNC:33743 CXorf66
neXtProtiNX_Q5JRM2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini20 – 47ExtracellularSequence analysisAdd BLAST28
Transmembranei48 – 68HelicalSequence analysisAdd BLAST21
Topological domaini69 – 361CytoplasmicSequence analysisAdd BLAST293

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

DisGeNETi347487
OpenTargetsiENSG00000203933
PharmGKBiPA164718516

Polymorphism and mutation databases

BioMutaiCXorf66
DMDMi74741872

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Sequence analysisAdd BLAST19
ChainiPRO_000034843420 – 361Uncharacterized protein CXorf66Add BLAST342

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi24N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ5JRM2
PeptideAtlasiQ5JRM2
PRIDEiQ5JRM2

PTM databases

iPTMnetiQ5JRM2
PhosphoSitePlusiQ5JRM2

Expressioni

Gene expression databases

BgeeiENSG00000203933

Organism-specific databases

HPAiHPA048517

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000359571

Structurei

3D structure databases

ProteinModelPortaliQ5JRM2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi91 – 177Ser-richAdd BLAST87

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J08X Eukaryota
ENOG41117EF LUCA
GeneTreeiENSGT00390000004226
HOGENOMiHOG000112110
InParanoidiQ5JRM2
OMAiFNPKRSV
OrthoDBiEOG091G0CJA
PhylomeDBiQ5JRM2
TreeFamiTF352168

Family and domain databases

InterProiView protein in InterPro
IPR038873 CXorf66
PANTHERiPTHR37340 PTHR37340, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q5JRM2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLVICVLLL SIWKNNCMTT NQTNGSSTTG DKPVESMQTK LNYLRRNLLI
60 70 80 90 100
LVGIIIMVFV FICFCYLHYN CLSDDASKAG MVKKKGIAAK SSKTSFSEAK
110 120 130 140 150
TASQCSPETQ PMLSTADKSS DSSSPERASA QSSTEKLIRP SSLQKPSIPN
160 170 180 190 200
SAGKLTRPSY PKRSSKSSCS KKLSKSSHLE KAHKKGSLEK LCKLDYACKL
210 220 230 240 250
ASSDKPVRPP QLFKPLYSSH PQNEISPSKP FGPQELAKPP KHFNPKRSVS
260 270 280 290 300
LGRAALLSNS ELAETCQPYK KKHLVAKTYR PLVNDISEAK EKNTQNLHVS
310 320 330 340 350
SKVKSSSRSF RKLDSRNNAY GDHVNDSDTM KYYSEVDSDK VIIITCDRGY
360
NQVTSEVTLN D
Length:361
Mass (Da):39,944
Last modified:February 15, 2005 - v1
Checksum:i3CC5814E66EA947C
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_046157233P → L. Corresponds to variant dbSNP:rs5955139Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590077 Genomic DNA No translation available.
BC137148 mRNA Translation: AAI37149.1
BC137149 mRNA Translation: AAI37150.1
CCDSiCCDS35411.1
RefSeqiNP_001013421.1, NM_001013403.2
UniGeneiHs.121384

Genome annotation databases

EnsembliENST00000370540; ENSP00000359571; ENSG00000203933
GeneIDi347487
KEGGihsa:347487
UCSCiuc004fbb.4 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCX066_HUMAN
AccessioniPrimary (citable) accession number: Q5JRM2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: February 15, 2005
Last modified: May 23, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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