Q5JQI0 (Q5JQI0_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
NEU1 protein EMBL CAG46714.1

Submitted name:
Sialidase 1 (Lysosomal sialidase), isoform CRA_a EMBL EAX03536.1
Submitted name:
cDNA, FLJ93471, Homo sapiens sialidase 1 (lysosomal sialidase) (NEU1), mRNA EMBL BAG35842.1

Gene names

Name:	NEU1 EMBL CAG46714.1
ORF Names:	hCG_43692 EMBL EAX03536.1

Organism

Homo sapiens (Human) EMBL BAG35842.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	415 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Cellular_component	cell junction Inferred from direct assay. Source: HPA intracellular membrane-bounded organelle Inferred from direct assay. Source: HPA lysosome Inferred from electronic annotation. Source: Compara
Molecular_function	exo-alpha-sialidase activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	415	1	EMBL CAG46714.1

Sequences

	Sequence		Length	Mass (Da)
	Q5JQI0 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: 360E60A256DEA07F	FASTA	415	45,467
	10 20 30 40 50 60 MTGERPSTAL PDRRWGPRIL GFWGGCRVWV FAAIFLLLSL AASWSKAEND FGLVQPLVTM 70 80 90 100 110 120 EQLLWVSGRQ IGSVDTFRIP LITATPRGTL LAFAEARKMS SSDEGAKFIA LRRSMDQGST 130 140 150 160 170 180 WSPTAFIVND GDVPDGLNLG AVVSDVETGV VFLFYSLCAH KAGCQVASTM LVWSKDDGVS 190 200 210 220 230 240 WSTPRNLSLD IGTEVFAPGP GSGIQKQREP RKGRLIVCGH GTLERDGVFC LLSDDHGASW 250 260 270 280 290 300 RYGSGVSGIP YGQPKQENDF NPDECQPYEL PDGSVVINAR NQNNYHCHCR IVLRSYDACD 310 320 330 340 350 360 TLRPRDVTFD PELVDPVVAA GAVVTSSGIV FFSNPAHPEF RVNLTLRWSF SNGTSWRKET 370 380 390 400 410 VQLWPGPSGY SSLATLEGSM DGEEQAPQLY VLYEKGRNHY TESISVAKIS VYGTL

References

[1]	"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)." Halleck A., Ebert L., Mkoundinya M., Schick M., Eisenstein S., Neubert P., Kstrang K., Schatten R., Shen B., Henze S., Mar W., Korn B., Zuo D., Hu Y., LaBaer J. Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	"NEDO functional analysis of protein and research application project." Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Cerebellum EMBL BAG35842.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK313006 mRNA. Translation: BAG35842.1. CR541916 mRNA. Translation: CAG46714.1. CH471081 Genomic DNA. Translation: EAX03536.1.
IPI	IPI00029817.
RefSeq	NP_000425.1. NM_000434.3.
UniGene	Hs.520037.
3D structure databases
ProteinModelPortal	Q5JQI0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5JQI0.
Protein family/group databases
CAZy	GH33. Glycoside Hydrolase Family 33.
Proteomic databases
PRIDE	Q5JQI0.
Protocols and materials databases
DNASU	4758.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4758.
KEGG	hsa:4758.
Organism-specific databases
CTD	4758.
PharmGKB	PA31560.
Phylogenomic databases
HOVERGEN	HBG057314.
KO	K01186.
OMA	YEKGRNQ.
PhylomeDB	Q5JQI0.
Gene expression databases
ArrayExpress	Q5JQI0.
Family and domain databases
Gene3D	2.120.10.10. 1 hit.
InterPro	IPR026942. Sialidase-1. IPR026856. Sialidase_fam. IPR011040. Sialidases. [Graphical view]
PANTHER	PTHR10628. PTHR10628. 1 hit. PTHR10628:SF9. PTHR10628:SF9. 1 hit.
SUPFAM	SSF50939. Sialidase. 1 hit.
ProtoNet	Search...
Other
ChiTaRS	NEU1. human.
GenomeRNAi	4758.
NextBio	18328.

Entry information

Entry name

Q5JQI0_HUMAN

Accession

Primary (citable) accession number: Q5JQI0

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	May 1, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.