Q5JQC4 (CT47A_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Cancer/testis antigen 47A

Alternative name(s):
Cancer/testis antigen 47
Short name=CT47

Gene names

Name:	CT47A1
Synonyms:	CT47.1
AND
Name:	CT47A2
Synonyms:	CT47.2
AND
Name:	CT47A3
Synonyms:	CT47.3
AND
Name:	CT47A4
Synonyms:	CT47.4
AND
Name:	CT47A5
Synonyms:	CT47.5
AND
Name:	CT47A6
Synonyms:	CT47.6
AND
Name:	CT47A7
Synonyms:	CT47.7
AND
Name:	CT47A8
Synonyms:	CT47.8
AND
Name:	CT47A9
Synonyms:	CT47.9
AND
Name:	CT47A10
Synonyms:	CT47.10
AND
Name:	CT47A11
Synonyms:	CT47.11
AND
Name:	CT47A12
Synonyms:	CT47.12

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	288 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Tissue specificity

Strongly expressed in testis, low expression in placenta, and very low expression in brain. Ref.3

Ontologies

Keywords
Domain	Coiled coil
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 288	288	Cancer/testis antigen 47A		PRO_0000284450
Regions
	Coiled coil	259 – 287	29	Potential
	Compositional bias	92 – 98	7	Poly-Glu
Experimental info
	Sequence conflict	161	1	L → P in AAH29540. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q5JQC4 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: AED9537B9C8EBF60	FASTA	288	30,100
	10 20 30 40 50 60 MSATGDRHPT QGDQEAPVSQ EGAQAEAAGA GNQEGGDSGP DSSDVVPAAE VVGVAGPVEG 70 80 90 100 110 120 LGEEEGEQAA GLAAVPRGGS AEEDSDIGPA TEEEEEEEGN EAANFDLAVV ARRYPASGIH 130 140 150 160 170 180 FVLLDMVHSL LHRLSHNDHI LIENRQLSRL MVGPHAAARN LWGNLPPLLL PQRLGAGAAA 190 200 210 220 230 240 RAGEGLGLIQ EAASVPEPAV PADLAEMARE PAEEAAEEKL SEEATEEPDA EEPATEEPTA 250 260 270 280 QEATAPEEVT KSQPEKWDEE AQDAAGEEEK EQEKEKDAEN KVKNSKGT

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence of the human X chromosome." Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C. , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R. Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Testis.
[3]	"Identification of a new cancer/testis gene family, CT47, among expressed multicopy genes on the human X chromosome." Chen Y.-T., Iseli C., Venditti C.A., Old L.J., Simpson A.J.G., Jongeneel C.V. Genes Chromosomes Cancer 45:392-400(2006) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION, TISSUE SPECIFICITY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL670379 Genomic DNA. Translation: CAI42057.1. AL670379 Genomic DNA. Translation: CAI42058.1. AL670379 Genomic DNA. Translation: CAI42059.1. AL670379 Genomic DNA. Translation: CAI42060.1. AL670379 Genomic DNA. Translation: CAI42061.1. AL670379 Genomic DNA. Translation: CAI42062.1. AL670379 Genomic DNA. Translation: CAI42063.1. AL670379 Genomic DNA. Translation: CAI42064.1. AL670379 Genomic DNA. Translation: CAI42065.1. AL670379 Genomic DNA. Translation: CAI42066.1. AL670379 Genomic DNA. Translation: CAI42067.1. AC008162 Genomic DNA. No translation available. BC029540 mRNA. Translation: AAH29540.1.
IPI	IPI00167090.
RefSeq	NP_001073606.1. NM_001080137.1. NP_001073607.1. NM_001080138.1. NP_001073608.1. NM_001080139.1. NP_001073609.1. NM_001080140.1. NP_001073610.1. NM_001080141.1. NP_001073611.1. NM_001080142.1. NP_001073612.1. NM_001080143.1. NP_001073613.1. NM_001080144.1. NP_001073614.1. NM_001080145.1. NP_001073615.1. NM_001080146.1. NP_001229851.1. NM_001242922.1. NP_775842.2. NM_173571.2.
UniGene	Hs.522775. Hs.712504. Hs.715076. Hs.723061. Hs.729566.
3D structure databases
ProteinModelPortal	Q5JQC4.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000360328.
PTM databases
PhosphoSite	Q5JQC4.
Proteomic databases
PaxDb	Q5JQC4.
PeptideAtlas	Q5JQC4.
PRIDE	Q5JQC4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000371280; ENSP00000360328; ENSG00000236371. ENST00000415858; ENSP00000389513; ENSG00000230594. ENST00000416816; ENSP00000414509; ENSG00000226685. ENST00000417256; ENSP00000408204; ENSG00000226600. ENST00000419194; ENSP00000399711; ENSG00000237957. ENST00000419982; ENSP00000391318; ENSG00000226685. ENST00000430448; ENSP00000411909; ENSG00000224089. ENST00000433030; ENSP00000393315; ENSG00000236371. ENST00000434414; ENSP00000404093; ENSG00000236371. ENST00000434883; ENSP00000392283; ENSG00000228517. ENST00000439466; ENSP00000390070; ENSG00000237957. ENST00000441330; ENSP00000398559; ENSG00000236126. ENST00000443600; ENSP00000415974; ENSG00000226023. ENST00000457020; ENSP00000410400; ENSG00000226929. ENST00000457977; ENSP00000400046; ENSG00000230347. ENST00000458218; ENSP00000414253; ENSG00000242362.
GeneID	100507170. 255313. 653282. 728036. 728042. 728049. 728062. 728072. 728075. 728082. 728090. 728096.
KEGG	hsa:100507170. hsa:255313. hsa:653282. hsa:728036. hsa:728042. hsa:728049. hsa:728062. hsa:728072. hsa:728075. hsa:728082. hsa:728090. hsa:728096.
UCSC	uc004eta.3. human.
Organism-specific databases
CTD	100507170. 255313. 653282. 728036. 728042. 728049. 728062. 728072. 728075. 728082. 728090. 728096.
GeneCards	GC0XM120012. GC0XM120067. GC0XM120072. GC0XM120077. GC0XM120082. GC0XM120087. GC0XM120092. GC0XM120093. GC0XM120101. GC0XM120106. GC0XM120111. GC0XM120112.
HGNC	HGNC:33282. CT47A1. HGNC:33291. CT47A10. HGNC:27397. CT47A11. HGNC:33292. CT47A12. HGNC:33283. CT47A2. HGNC:33284. CT47A3. HGNC:33285. CT47A4. HGNC:33286. CT47A5. HGNC:33287. CT47A6. HGNC:33288. CT47A7. HGNC:33289. CT47A8. HGNC:33290. CT47A9.
HPA	HPA042483.
MIM	300592. gene. 300780. gene. 300781. gene. 300782. gene. 300783. gene. 300784. gene. 300785. gene. 300786. gene. 300787. gene. 300788. gene. 300789. gene.
neXtProt	NX_Q5JQC4.
PharmGKB	PA164718206.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG130989.
HOGENOM	HOG000112037.
HOVERGEN	HBG094803.
InParanoid	Q5JQC4.
OMA	RLSHNDH.
OrthoDB	EOG4S4PJ0.
Gene expression databases
Bgee	Q5JQC4.
Genevestigator	Q5JQC4.
Family and domain databases
ProtoNet	Search...
Other
NextBio	92541.
SOURCE	Search...

Entry information

Entry name

CT47A_HUMAN

Accession

Primary (citable) accession number: Q5JQC4
Secondary accession number(s): Q8N747

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 17, 2007
Last sequence update:	February 15, 2005
Last modified:	April 3, 2013
This is version 72 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.