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Q5JQC4

- CT47A_HUMAN

UniProt

Q5JQC4 - CT47A_HUMAN

Protein

Cancer/testis antigen 47A

Gene

CT47A1

more
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (15 Feb 2005)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cancer/testis antigen 47A
    Alternative name(s):
    Cancer/testis antigen 47
    Short name:
    CT47
    Gene namesi
    Name:CT47A1
    Synonyms:CT47.1
    AND
    Name:CT47A2
    Synonyms:CT47.2
    AND
    Name:CT47A3
    Synonyms:CT47.3
    AND
    Name:CT47A4
    Synonyms:CT47.4
    AND
    Name:CT47A5
    Synonyms:CT47.5
    AND
    Name:CT47A6
    Synonyms:CT47.6
    AND
    Name:CT47A7
    Synonyms:CT47.7
    AND
    Name:CT47A8
    Synonyms:CT47.8
    AND
    Name:CT47A9
    Synonyms:CT47.9
    AND
    Name:CT47A10
    Synonyms:CT47.10
    AND
    Name:CT47A11
    Synonyms:CT47.11
    AND
    Name:CT47A12
    Synonyms:CT47.12
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome X

    Organism-specific databases

    HGNCiHGNC:33282. CT47A1.
    HGNC:33291. CT47A10.
    HGNC:27397. CT47A11.
    HGNC:33292. CT47A12.
    HGNC:33283. CT47A2.
    HGNC:33284. CT47A3.
    HGNC:33285. CT47A4.
    HGNC:33286. CT47A5.
    HGNC:33287. CT47A6.
    HGNC:33288. CT47A7.
    HGNC:33289. CT47A8.
    HGNC:33290. CT47A9.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA164718206.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 288288Cancer/testis antigen 47APRO_0000284450Add
    BLAST

    Proteomic databases

    MaxQBiQ5JQC4.
    PaxDbiQ5JQC4.
    PeptideAtlasiQ5JQC4.
    PRIDEiQ5JQC4.

    PTM databases

    PhosphoSiteiQ5JQC4.

    Expressioni

    Tissue specificityi

    Strongly expressed in testis, low expression in placenta, and very low expression in brain.1 Publication

    Gene expression databases

    BgeeiQ5JQC4.
    GenevestigatoriQ5JQC4.

    Organism-specific databases

    HPAiHPA042483.

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000360328.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5JQC4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili259 – 28729Sequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi92 – 987Poly-Glu

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiNOG130989.
    HOGENOMiHOG000112037.
    HOVERGENiHBG094803.
    InParanoidiQ5JQC4.
    OMAiRLSHNDH.
    OrthoDBiEOG71CFNT.
    PhylomeDBiQ5JQC4.
    TreeFamiTF342556.

    Family and domain databases

    InterProiIPR028930. CT47.
    [Graphical view]
    PANTHERiPTHR32157. PTHR32157. 1 hit.
    PfamiPF15623. CT47. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5JQC4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSATGDRHPT QGDQEAPVSQ EGAQAEAAGA GNQEGGDSGP DSSDVVPAAE    50
    VVGVAGPVEG LGEEEGEQAA GLAAVPRGGS AEEDSDIGPA TEEEEEEEGN 100
    EAANFDLAVV ARRYPASGIH FVLLDMVHSL LHRLSHNDHI LIENRQLSRL 150
    MVGPHAAARN LWGNLPPLLL PQRLGAGAAA RAGEGLGLIQ EAASVPEPAV 200
    PADLAEMARE PAEEAAEEKL SEEATEEPDA EEPATEEPTA QEATAPEEVT 250
    KSQPEKWDEE AQDAAGEEEK EQEKEKDAEN KVKNSKGT 288
    Length:288
    Mass (Da):30,100
    Last modified:February 15, 2005 - v1
    Checksum:iAED9537B9C8EBF60
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti161 – 1611L → P in AAH29540. (PubMed:15489334)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL670379 Genomic DNA. Translation: CAI42057.1.
    AL670379 Genomic DNA. Translation: CAI42058.1.
    AL670379 Genomic DNA. Translation: CAI42059.1.
    AL670379 Genomic DNA. Translation: CAI42060.1.
    AL670379 Genomic DNA. Translation: CAI42061.1.
    AL670379 Genomic DNA. Translation: CAI42062.1.
    AL670379 Genomic DNA. Translation: CAI42063.1.
    AL670379 Genomic DNA. Translation: CAI42064.1.
    AL670379 Genomic DNA. Translation: CAI42065.1.
    AL670379 Genomic DNA. Translation: CAI42066.1.
    AL670379 Genomic DNA. Translation: CAI42067.1.
    AC008162 Genomic DNA. No translation available.
    BC029540 mRNA. Translation: AAH29540.1.
    CCDSiCCDS35381.1.
    CCDS35382.1.
    CCDS35383.1.
    CCDS35384.1.
    CCDS35385.1.
    CCDS35386.1.
    CCDS35387.1.
    CCDS35388.1.
    CCDS35389.1.
    CCDS35390.1.
    CCDS35391.1.
    CCDS56607.1.
    RefSeqiNP_001073606.1. NM_001080137.1.
    NP_001073607.1. NM_001080138.1.
    NP_001073608.1. NM_001080139.1.
    NP_001073609.1. NM_001080140.1.
    NP_001073610.1. NM_001080141.1.
    NP_001073611.1. NM_001080142.1.
    NP_001073612.1. NM_001080143.1.
    NP_001073613.1. NM_001080144.1.
    NP_001073614.1. NM_001080145.1.
    NP_001073615.1. NM_001080146.1.
    NP_001229851.1. NM_001242922.1.
    NP_775842.2. NM_173571.2.
    UniGeneiHs.522775.
    Hs.712504.
    Hs.715076.
    Hs.723061.
    Hs.729566.

    Genome annotation databases

    EnsembliENST00000415858; ENSP00000389513; ENSG00000230594.
    ENST00000416816; ENSP00000414509; ENSG00000226685.
    ENST00000417256; ENSP00000408204; ENSG00000226600.
    ENST00000419194; ENSP00000399711; ENSG00000226023.
    ENST00000419982; ENSP00000391318; ENSG00000226685.
    ENST00000430448; ENSP00000411909; ENSG00000224089.
    ENST00000433030; ENSP00000393315; ENSG00000236371.
    ENST00000434883; ENSP00000392283; ENSG00000228517.
    ENST00000439466; ENSP00000390070; ENSG00000237957.
    ENST00000441330; ENSP00000398559; ENSG00000236126.
    ENST00000443600; ENSP00000415974; ENSG00000226023.
    ENST00000457020; ENSP00000410400; ENSG00000226929.
    ENST00000457977; ENSP00000400046; ENSG00000230347.
    ENST00000458218; ENSP00000414253; ENSG00000242362.
    GeneIDi100507170.
    255313.
    653282.
    728036.
    728042.
    728049.
    728062.
    728072.
    728075.
    728082.
    728090.
    728096.
    KEGGihsa:100507170.
    hsa:255313.
    hsa:653282.
    hsa:728036.
    hsa:728042.
    hsa:728049.
    hsa:728062.
    hsa:728072.
    hsa:728075.
    hsa:728082.
    hsa:728090.
    hsa:728096.
    UCSCiuc004eta.3. human.

    Polymorphism databases

    DMDMi74741726.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL670379 Genomic DNA. Translation: CAI42057.1 .
    AL670379 Genomic DNA. Translation: CAI42058.1 .
    AL670379 Genomic DNA. Translation: CAI42059.1 .
    AL670379 Genomic DNA. Translation: CAI42060.1 .
    AL670379 Genomic DNA. Translation: CAI42061.1 .
    AL670379 Genomic DNA. Translation: CAI42062.1 .
    AL670379 Genomic DNA. Translation: CAI42063.1 .
    AL670379 Genomic DNA. Translation: CAI42064.1 .
    AL670379 Genomic DNA. Translation: CAI42065.1 .
    AL670379 Genomic DNA. Translation: CAI42066.1 .
    AL670379 Genomic DNA. Translation: CAI42067.1 .
    AC008162 Genomic DNA. No translation available.
    BC029540 mRNA. Translation: AAH29540.1 .
    CCDSi CCDS35381.1.
    CCDS35382.1.
    CCDS35383.1.
    CCDS35384.1.
    CCDS35385.1.
    CCDS35386.1.
    CCDS35387.1.
    CCDS35388.1.
    CCDS35389.1.
    CCDS35390.1.
    CCDS35391.1.
    CCDS56607.1.
    RefSeqi NP_001073606.1. NM_001080137.1.
    NP_001073607.1. NM_001080138.1.
    NP_001073608.1. NM_001080139.1.
    NP_001073609.1. NM_001080140.1.
    NP_001073610.1. NM_001080141.1.
    NP_001073611.1. NM_001080142.1.
    NP_001073612.1. NM_001080143.1.
    NP_001073613.1. NM_001080144.1.
    NP_001073614.1. NM_001080145.1.
    NP_001073615.1. NM_001080146.1.
    NP_001229851.1. NM_001242922.1.
    NP_775842.2. NM_173571.2.
    UniGenei Hs.522775.
    Hs.712504.
    Hs.715076.
    Hs.723061.
    Hs.729566.

    3D structure databases

    ProteinModelPortali Q5JQC4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000360328.

    PTM databases

    PhosphoSitei Q5JQC4.

    Polymorphism databases

    DMDMi 74741726.

    Proteomic databases

    MaxQBi Q5JQC4.
    PaxDbi Q5JQC4.
    PeptideAtlasi Q5JQC4.
    PRIDEi Q5JQC4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000415858 ; ENSP00000389513 ; ENSG00000230594 .
    ENST00000416816 ; ENSP00000414509 ; ENSG00000226685 .
    ENST00000417256 ; ENSP00000408204 ; ENSG00000226600 .
    ENST00000419194 ; ENSP00000399711 ; ENSG00000226023 .
    ENST00000419982 ; ENSP00000391318 ; ENSG00000226685 .
    ENST00000430448 ; ENSP00000411909 ; ENSG00000224089 .
    ENST00000433030 ; ENSP00000393315 ; ENSG00000236371 .
    ENST00000434883 ; ENSP00000392283 ; ENSG00000228517 .
    ENST00000439466 ; ENSP00000390070 ; ENSG00000237957 .
    ENST00000441330 ; ENSP00000398559 ; ENSG00000236126 .
    ENST00000443600 ; ENSP00000415974 ; ENSG00000226023 .
    ENST00000457020 ; ENSP00000410400 ; ENSG00000226929 .
    ENST00000457977 ; ENSP00000400046 ; ENSG00000230347 .
    ENST00000458218 ; ENSP00000414253 ; ENSG00000242362 .
    GeneIDi 100507170.
    255313.
    653282.
    728036.
    728042.
    728049.
    728062.
    728072.
    728075.
    728082.
    728090.
    728096.
    KEGGi hsa:100507170.
    hsa:255313.
    hsa:653282.
    hsa:728036.
    hsa:728042.
    hsa:728049.
    hsa:728062.
    hsa:728072.
    hsa:728075.
    hsa:728082.
    hsa:728090.
    hsa:728096.
    UCSCi uc004eta.3. human.

    Organism-specific databases

    CTDi 100507170.
    255313.
    653282.
    728036.
    728042.
    728049.
    728062.
    728072.
    728075.
    728082.
    728090.
    728096.
    GeneCardsi GC0XM120012.
    GC0XM120067.
    GC0XM120072.
    GC0XM120077.
    GC0XM120082.
    GC0XM120087.
    GC0XM120092.
    GC0XM120093.
    GC0XM120101.
    GC0XM120106.
    GC0XM120111.
    GC0XM120112.
    HGNCi HGNC:33282. CT47A1.
    HGNC:33291. CT47A10.
    HGNC:27397. CT47A11.
    HGNC:33292. CT47A12.
    HGNC:33283. CT47A2.
    HGNC:33284. CT47A3.
    HGNC:33285. CT47A4.
    HGNC:33286. CT47A5.
    HGNC:33287. CT47A6.
    HGNC:33288. CT47A7.
    HGNC:33289. CT47A8.
    HGNC:33290. CT47A9.
    HPAi HPA042483.
    MIMi 300592. gene.
    300780. gene.
    300781. gene.
    300782. gene.
    300783. gene.
    300784. gene.
    300785. gene.
    300786. gene.
    300787. gene.
    300788. gene.
    300789. gene.
    neXtProti NX_Q5JQC4.
    PharmGKBi PA164718206.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG130989.
    HOGENOMi HOG000112037.
    HOVERGENi HBG094803.
    InParanoidi Q5JQC4.
    OMAi RLSHNDH.
    OrthoDBi EOG71CFNT.
    PhylomeDBi Q5JQC4.
    TreeFami TF342556.

    Miscellaneous databases

    NextBioi 92541.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q5JQC4.
    Genevestigatori Q5JQC4.

    Family and domain databases

    InterProi IPR028930. CT47.
    [Graphical view ]
    PANTHERi PTHR32157. PTHR32157. 1 hit.
    Pfami PF15623. CT47. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The DNA sequence of the human X chromosome."
      Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
      , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
      Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Testis.
    3. "Identification of a new cancer/testis gene family, CT47, among expressed multicopy genes on the human X chromosome."
      Chen Y.-T., Iseli C., Venditti C.A., Old L.J., Simpson A.J.G., Jongeneel C.V.
      Genes Chromosomes Cancer 45:392-400(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION, TISSUE SPECIFICITY.

    Entry informationi

    Entry nameiCT47A_HUMAN
    AccessioniPrimary (citable) accession number: Q5JQC4
    Secondary accession number(s): Q8N747
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 17, 2007
    Last sequence update: February 15, 2005
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome X
      Human chromosome X: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

    External Data

    Dasty 3