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Protein
Submitted name:

Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Gene

PDHA1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrialImported
Gene namesi
Name:PDHA1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000131828.13
HGNCiHGNC:8806 PDHA1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000131828

PTM / Processingi

Proteomic databases

MaxQBiQ5JPU3
PeptideAtlasiQ5JPU3
PRIDEiQ5JPU3

Expressioni

Gene expression databases

BgeeiENSG00000131828
ExpressionAtlasiQ5JPU3 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5JPU3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 80E1_dhInterPro annotationAdd BLAST80

Phylogenomic databases

eggNOGiKOG0225 Eukaryota
COG1071 LUCA
GeneTreeiENSGT00530000063174
HOGENOMiHOG000138172

Family and domain databases

InterProiView protein in InterPro
IPR001017 DH_E1
IPR029061 THDP-binding
PfamiView protein in Pfam
PF00676 E1_dh, 1 hit
SUPFAMiSSF52518 SSF52518, 1 hit

Sequencei

Sequence statusi: Complete.

Q5JPU3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELQTYRYHG HSMSDPGVSY RTREEIQEVR SKSDPIMLLK DRMVNSNLAS
60 70 80 90 100
VEELKEIDVE VRKEIEDAAQ FATADPEPPL EELGYHIYSS DPPFEVRGAN

QWIKFKSVS
Length:109
Mass (Da):12,588
Last modified:February 15, 2005 - v1
Checksum:i60DAC681847CC89C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL732326 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000379804; ENSP00000369132; ENSG00000131828
UCSCiuc064ygm.1 human

Similar proteinsi

Entry informationi

Entry nameiQ5JPU3_HUMAN
AccessioniPrimary (citable) accession number: Q5JPU3
Entry historyiIntegrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: May 23, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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