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Protein
Submitted name:

Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Gene

PDHA1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrialImported
Gene namesi
Name:PDHA1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

HGNCiHGNC:8806. PDHA1.

PTM / Processingi

Proteomic databases

PaxDbiQ5JPU3.
PeptideAtlasiQ5JPU3.
PRIDEiQ5JPU3.

Expressioni

Gene expression databases

BgeeiENSG00000131828.
ExpressionAtlasiQ5JPU3. baseline and differential.

Interactioni

Protein-protein interaction databases

MINTiMINT-1417364.
STRINGi9606.ENSP00000369134.

Structurei

3D structure databases

ProteinModelPortaliQ5JPU3.
SMRiQ5JPU3. Positions 1-109.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 8080E1_dhInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG0225. Eukaryota.
COG1071. LUCA.
GeneTreeiENSGT00530000063174.
HOGENOMiHOG000138172.

Family and domain databases

Gene3Di3.40.50.970. 1 hit.
InterProiIPR001017. DH_E1.
IPR029061. THDP-binding.
[Graphical view]
PfamiPF00676. E1_dh. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5JPU3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELQTYRYHG HSMSDPGVSY RTREEIQEVR SKSDPIMLLK DRMVNSNLAS
60 70 80 90 100
VEELKEIDVE VRKEIEDAAQ FATADPEPPL EELGYHIYSS DPPFEVRGAN

QWIKFKSVS
Length:109
Mass (Da):12,588
Last modified:February 15, 2005 - v1
Checksum:i60DAC681847CC89C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL732326 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000379804; ENSP00000369132; ENSG00000131828.
UCSCiuc064ygm.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL732326 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliQ5JPU3.
SMRiQ5JPU3. Positions 1-109.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-1417364.
STRINGi9606.ENSP00000369134.

Proteomic databases

PaxDbiQ5JPU3.
PeptideAtlasiQ5JPU3.
PRIDEiQ5JPU3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000379804; ENSP00000369132; ENSG00000131828.
UCSCiuc064ygm.1. human.

Organism-specific databases

HGNCiHGNC:8806. PDHA1.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0225. Eukaryota.
COG1071. LUCA.
GeneTreeiENSGT00530000063174.
HOGENOMiHOG000138172.

Miscellaneous databases

ChiTaRSiPDHA1. human.

Gene expression databases

BgeeiENSG00000131828.
ExpressionAtlasiQ5JPU3. baseline and differential.

Family and domain databases

Gene3Di3.40.50.970. 1 hit.
InterProiIPR001017. DH_E1.
IPR029061. THDP-binding.
[Graphical view]
PfamiPF00676. E1_dh. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ5JPU3_HUMAN
AccessioniPrimary (citable) accession number: Q5JPU3
Entry historyi
Integrated into UniProtKB/TrEMBL: February 15, 2005
Last sequence update: February 15, 2005
Last modified: September 7, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.