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Q5JPB2

- ZN831_HUMAN

UniProt

Q5JPB2 - ZN831_HUMAN

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Protein

Zinc finger protein 831

Gene

ZNF831

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri144 – 16623C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri172 – 19625C2H2-type 2PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. nucleic acid binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 831
Gene namesi
Name:ZNF831
Synonyms:C20orf174
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 20

Organism-specific databases

HGNCiHGNC:16167. ZNF831.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162410774.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 16771677Zinc finger protein 831PRO_0000236041Add
BLAST

Proteomic databases

MaxQBiQ5JPB2.
PaxDbiQ5JPB2.
PRIDEiQ5JPB2.

PTM databases

PhosphoSiteiQ5JPB2.

Expressioni

Gene expression databases

BgeeiQ5JPB2.
CleanExiHS_ZNF831.
GenevestigatoriQ5JPB2.

Organism-specific databases

HPAiHPA016839.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000360069.

Structurei

3D structure databases

ProteinModelPortaliQ5JPB2.
SMRiQ5JPB2. Positions 142-190.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili391 – 42333Sequence AnalysisAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi4 – 111108Pro-richAdd
BLAST

Sequence similaritiesi

Contains 2 C2H2-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri144 – 16623C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri172 – 19625C2H2-type 2PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Coiled coil, Repeat, Zinc-finger

Phylogenomic databases

eggNOGiNOG331219.
GeneTreeiENSGT00530000063161.
HOGENOMiHOG000231308.
HOVERGENiHBG080221.
InParanoidiQ5JPB2.
OMAiSPGKVRN.
OrthoDBiEOG769ZHP.
PhylomeDBiQ5JPB2.
TreeFamiTF338213.

Family and domain databases

Gene3Di3.30.160.60. 2 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 2 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5JPB2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEVPEPTCPA PPARDQPAPT PGPPGAPGGQ ASPHLTLGPV LLPPEQGLAP
60 70 80 90 100
PTVFLKALPI PLYHTVPPGG LQPRAPLVTG SLDGGNVPFI LSPVLQPEGP
110 120 130 140 150
GPTQVGKPAA PTLTVNIVGT LPVLSPGLGP TLGSPGKVRN AGKYLCPHCG
160 170 180 190 200
RDCLKPSVLE KHIRSHTGER PFPCATCGIA FKTQSNLYKH RRTQTHLNNS
210 220 230 240 250
RLSSESEGAG GGLLEEGDKA GEPPRPEGRG ESRCQGMHEG ASERPLSPGA
260 270 280 290 300
HVPLLAKNLD VRTEAAPCPG SAFADREAPW DSAPMASPGL PAASTQPWRK
310 320 330 340 350
LPEQKSPTAG KPCALQRQQA TAAEKPWDAK APEGRLRKCE STDSGYLSRS
360 370 380 390 400
DSAEQPHAPC SPLHSLSEHS AESEGEGGPG PGPGVAGAEP GAREAGLELE
410 420 430 440 450
KKRLEERIAQ LISHNQAVVD DAQLDNVRPR KTGLSKQGSI DLPTPYTYKD
460 470 480 490 500
SFHFDIRALE PGRRRAPGPV RSTWTPPDKS RPLFFHSVPT QLSTTVECVP
510 520 530 540 550
VTRSNSLPFV EGSRTWLEPR EPRDPWSRTQ KPLSPRPGPA RLGCRSGLSS
560 570 580 590 600
TDVPSGHPRA LVRQAAVEDL PGTPIGDALV PAEDTDAKRT AAREAMAGKG
610 620 630 640 650
RAGGRKCGQR RLKMFSQEKW QVYGDETFKR IYQKMKASPH GGKKAREVGM
660 670 680 690 700
GSGAELGFPL QKEAAGSSGT VPTQDRRTPV HEDISAGATP EPWGNPPALE
710 720 730 740 750
ASLVTEPTKH GETVARRGDS DRPRVEEAVS SPALGGRDSP CSGSRSPLVS
760 770 780 790 800
PNGRLELGWQ MPPAPGPLKG GDVEAPRPVW PDPKLEGGAR GVGDVQETCL
810 820 830 840 850
WAQTVLRWPS RGSGEDKLPS ERKKLKVEDL HSWKQPEPVS AETPGGPTQP
860 870 880 890 900
ASLSSQKQDA DPGEVPGGSK ESARQVGEPL ESSGASLAAA SVALKRVGPR
910 920 930 940 950
DKATPLHPAA PAPAEHPSLA TPPQAPRVLS ALADNAFSPK YLLRLPQAET
960 970 980 990 1000
PLPLPIPWGP RHSQDSLCSS GWPEERASFV GSGLGTPLSP SPASGPSPGE
1010 1020 1030 1040 1050
ADSILEDPSC SRPQDGRKGA QLGGDKGDRM ATSRPAAREL PISAPGAPRE
1060 1070 1080 1090 1100
ATSSPPTPTC EAHLVQDMEG DSHRIHRLCM GSTLARARLS GDVLNPWVPN
1110 1120 1130 1140 1150
WELGEPPGNA PEDPSSGPLV GPDPCSPLQP GSFLTALTRP QGVPPGWPEL
1160 1170 1180 1190 1200
ALSSHSGTSR SHSTRSPHST QNPFPSLKAE PRLTWCCLSR SVPLPAEQKA
1210 1220 1230 1240 1250
KAASVYLAVH FPGSSLRDEG PNGPPGSNGG WTWTSPGEGG PAQMSKFSYP
1260 1270 1280 1290 1300
TVPGVMPQHQ VSEPEWKKGL PWRAKMSRGN SKQRKLKINP KRYKGNFLQS
1310 1320 1330 1340 1350
CVQLRASRLR TPTWVRRRSR HPPALEGLKP CRTPGQTSSE IAGLNLQEEP
1360 1370 1380 1390 1400
SCATSESPPC CGKEEKKEGD CRQTLGTLSL GTSSRIVREM DKRTVKDISP
1410 1420 1430 1440 1450
SAGEHGDCTT HSTAATSGLS LQSDTCLAVV NDVPLPPGKG LDLGLLETQL
1460 1470 1480 1490 1500
LASQDSVSTD PKPYIFSDAQ RPSSFGSKGT FPHHDIATSV AAVCISLPVR
1510 1520 1530 1540 1550
TDHIAQEIHS AESRDHSQTA GRTLTSSSPD SKVTEEGRAQ TLLPGRPSSG
1560 1570 1580 1590 1600
QRISDSVPLE STEKTHLEIP ASGPSSASSH HKEGRHKTFF PSRGQYGCGE
1610 1620 1630 1640 1650
MTVPCPSLGS DGRKRQVSGL ITRKDSVVPS KPEQPIEIPE APSKSLKKRS
1660 1670
LEGMRKQTRV EFSDTSSDDE DRLVIEI
Length:1,677
Mass (Da):177,949
Last modified:October 23, 2007 - v4
Checksum:iD4D23943AAC3DA89
GO

Sequence cautioni

The sequence CAI46154.1 differs from that shown. Reason: Erroneous initiation. Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti845 – 8451G → R.
Corresponds to variant rs181984 [ dbSNP | Ensembl ].
VAR_026472
Natural varianti1513 – 15131S → P.
Corresponds to variant rs259956 [ dbSNP | Ensembl ].
VAR_026473
Natural varianti1615 – 16151R → H.1 Publication
VAR_069367

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121919 Genomic DNA. Translation: CAI21544.2.
AL713683 mRNA. Translation: CAD28487.1.
AL833682 mRNA. Translation: CAI46154.1. Different initiation.
CCDSiCCDS42894.1.
RefSeqiNP_848552.1. NM_178457.2.
XP_005260329.1. XM_005260272.1.
XP_005260330.1. XM_005260273.1.
XP_005260331.1. XM_005260274.1.
XP_006723761.1. XM_006723698.1.
UniGeneiHs.473204.

Genome annotation databases

EnsembliENST00000371030; ENSP00000360069; ENSG00000124203.
GeneIDi128611.
KEGGihsa:128611.
UCSCiuc002yan.3. human.

Polymorphism databases

DMDMi160370001.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL121919 Genomic DNA. Translation: CAI21544.2 .
AL713683 mRNA. Translation: CAD28487.1 .
AL833682 mRNA. Translation: CAI46154.1 . Different initiation.
CCDSi CCDS42894.1.
RefSeqi NP_848552.1. NM_178457.2.
XP_005260329.1. XM_005260272.1.
XP_005260330.1. XM_005260273.1.
XP_005260331.1. XM_005260274.1.
XP_006723761.1. XM_006723698.1.
UniGenei Hs.473204.

3D structure databases

ProteinModelPortali Q5JPB2.
SMRi Q5JPB2. Positions 142-190.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9606.ENSP00000360069.

PTM databases

PhosphoSitei Q5JPB2.

Polymorphism databases

DMDMi 160370001.

Proteomic databases

MaxQBi Q5JPB2.
PaxDbi Q5JPB2.
PRIDEi Q5JPB2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000371030 ; ENSP00000360069 ; ENSG00000124203 .
GeneIDi 128611.
KEGGi hsa:128611.
UCSCi uc002yan.3. human.

Organism-specific databases

CTDi 128611.
GeneCardsi GC20P057766.
HGNCi HGNC:16167. ZNF831.
HPAi HPA016839.
neXtProti NX_Q5JPB2.
PharmGKBi PA162410774.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG331219.
GeneTreei ENSGT00530000063161.
HOGENOMi HOG000231308.
HOVERGENi HBG080221.
InParanoidi Q5JPB2.
OMAi SPGKVRN.
OrthoDBi EOG769ZHP.
PhylomeDBi Q5JPB2.
TreeFami TF338213.

Miscellaneous databases

GenomeRNAii 128611.
NextBioi 82396.
PROi Q5JPB2.

Gene expression databases

Bgeei Q5JPB2.
CleanExi HS_ZNF831.
Genevestigatori Q5JPB2.

Family and domain databases

Gene3Di 3.30.160.60. 2 hits.
InterProi IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
SMARTi SM00355. ZnF_C2H2. 2 hits.
[Graphical view ]
PROSITEi PS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and comparative analysis of human chromosome 20."
    Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
    , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
    Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 379-1677.
    Tissue: Lymph node.
  3. Cited for: VARIANT HIS-1615.

Entry informationi

Entry nameiZN831_HUMAN
AccessioniPrimary (citable) accession number: Q5JPB2
Secondary accession number(s): Q5TDR4, Q8TCP0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: October 23, 2007
Last modified: October 29, 2014
This is version 79 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3