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Q5JPB2

- ZN831_HUMAN

UniProt

Q5JPB2 - ZN831_HUMAN

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Protein

Zinc finger protein 831

Gene
ZNF831, C20orf174
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri144 – 16623C2H2-type 1Add
BLAST
Zinc fingeri172 – 19625C2H2-type 2Add
BLAST

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. nucleic acid binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 831
Gene namesi
Name:ZNF831
Synonyms:C20orf174
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 20

Organism-specific databases

HGNCiHGNC:16167. ZNF831.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162410774.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 16771677Zinc finger protein 831PRO_0000236041Add
BLAST

Proteomic databases

PaxDbiQ5JPB2.
PRIDEiQ5JPB2.

PTM databases

PhosphoSiteiQ5JPB2.

Expressioni

Gene expression databases

BgeeiQ5JPB2.
CleanExiHS_ZNF831.
GenevestigatoriQ5JPB2.

Organism-specific databases

HPAiHPA016839.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000360069.

Structurei

3D structure databases

ProteinModelPortaliQ5JPB2.
SMRiQ5JPB2. Positions 142-190.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili391 – 42333 Reviewed predictionAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi4 – 111108Pro-richAdd
BLAST

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri144 – 16623C2H2-type 1Add
BLAST
Zinc fingeri172 – 19625C2H2-type 2Add
BLAST

Keywords - Domaini

Coiled coil, Repeat, Zinc-finger

Phylogenomic databases

eggNOGiNOG331219.
HOGENOMiHOG000231308.
HOVERGENiHBG080221.
InParanoidiQ5JPB2.
OMAiSPGKVRN.
OrthoDBiEOG769ZHP.
PhylomeDBiQ5JPB2.
TreeFamiTF338213.

Family and domain databases

Gene3Di3.30.160.60. 2 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 2 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5JPB2-1 [UniParc]FASTAAdd to Basket

« Hide

MEVPEPTCPA PPARDQPAPT PGPPGAPGGQ ASPHLTLGPV LLPPEQGLAP     50
PTVFLKALPI PLYHTVPPGG LQPRAPLVTG SLDGGNVPFI LSPVLQPEGP 100
GPTQVGKPAA PTLTVNIVGT LPVLSPGLGP TLGSPGKVRN AGKYLCPHCG 150
RDCLKPSVLE KHIRSHTGER PFPCATCGIA FKTQSNLYKH RRTQTHLNNS 200
RLSSESEGAG GGLLEEGDKA GEPPRPEGRG ESRCQGMHEG ASERPLSPGA 250
HVPLLAKNLD VRTEAAPCPG SAFADREAPW DSAPMASPGL PAASTQPWRK 300
LPEQKSPTAG KPCALQRQQA TAAEKPWDAK APEGRLRKCE STDSGYLSRS 350
DSAEQPHAPC SPLHSLSEHS AESEGEGGPG PGPGVAGAEP GAREAGLELE 400
KKRLEERIAQ LISHNQAVVD DAQLDNVRPR KTGLSKQGSI DLPTPYTYKD 450
SFHFDIRALE PGRRRAPGPV RSTWTPPDKS RPLFFHSVPT QLSTTVECVP 500
VTRSNSLPFV EGSRTWLEPR EPRDPWSRTQ KPLSPRPGPA RLGCRSGLSS 550
TDVPSGHPRA LVRQAAVEDL PGTPIGDALV PAEDTDAKRT AAREAMAGKG 600
RAGGRKCGQR RLKMFSQEKW QVYGDETFKR IYQKMKASPH GGKKAREVGM 650
GSGAELGFPL QKEAAGSSGT VPTQDRRTPV HEDISAGATP EPWGNPPALE 700
ASLVTEPTKH GETVARRGDS DRPRVEEAVS SPALGGRDSP CSGSRSPLVS 750
PNGRLELGWQ MPPAPGPLKG GDVEAPRPVW PDPKLEGGAR GVGDVQETCL 800
WAQTVLRWPS RGSGEDKLPS ERKKLKVEDL HSWKQPEPVS AETPGGPTQP 850
ASLSSQKQDA DPGEVPGGSK ESARQVGEPL ESSGASLAAA SVALKRVGPR 900
DKATPLHPAA PAPAEHPSLA TPPQAPRVLS ALADNAFSPK YLLRLPQAET 950
PLPLPIPWGP RHSQDSLCSS GWPEERASFV GSGLGTPLSP SPASGPSPGE 1000
ADSILEDPSC SRPQDGRKGA QLGGDKGDRM ATSRPAAREL PISAPGAPRE 1050
ATSSPPTPTC EAHLVQDMEG DSHRIHRLCM GSTLARARLS GDVLNPWVPN 1100
WELGEPPGNA PEDPSSGPLV GPDPCSPLQP GSFLTALTRP QGVPPGWPEL 1150
ALSSHSGTSR SHSTRSPHST QNPFPSLKAE PRLTWCCLSR SVPLPAEQKA 1200
KAASVYLAVH FPGSSLRDEG PNGPPGSNGG WTWTSPGEGG PAQMSKFSYP 1250
TVPGVMPQHQ VSEPEWKKGL PWRAKMSRGN SKQRKLKINP KRYKGNFLQS 1300
CVQLRASRLR TPTWVRRRSR HPPALEGLKP CRTPGQTSSE IAGLNLQEEP 1350
SCATSESPPC CGKEEKKEGD CRQTLGTLSL GTSSRIVREM DKRTVKDISP 1400
SAGEHGDCTT HSTAATSGLS LQSDTCLAVV NDVPLPPGKG LDLGLLETQL 1450
LASQDSVSTD PKPYIFSDAQ RPSSFGSKGT FPHHDIATSV AAVCISLPVR 1500
TDHIAQEIHS AESRDHSQTA GRTLTSSSPD SKVTEEGRAQ TLLPGRPSSG 1550
QRISDSVPLE STEKTHLEIP ASGPSSASSH HKEGRHKTFF PSRGQYGCGE 1600
MTVPCPSLGS DGRKRQVSGL ITRKDSVVPS KPEQPIEIPE APSKSLKKRS 1650
LEGMRKQTRV EFSDTSSDDE DRLVIEI 1677
Length:1,677
Mass (Da):177,949
Last modified:October 23, 2007 - v4
Checksum:iD4D23943AAC3DA89
GO

Sequence cautioni

The sequence CAI46154.1 differs from that shown. Reason: Erroneous initiation.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti845 – 8451G → R.
Corresponds to variant rs181984 [ dbSNP | Ensembl ].
VAR_026472
Natural varianti1513 – 15131S → P.
Corresponds to variant rs259956 [ dbSNP | Ensembl ].
VAR_026473
Natural varianti1615 – 16151R → H.1 Publication
VAR_069367

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL121919 Genomic DNA. Translation: CAI21544.2.
AL713683 mRNA. Translation: CAD28487.1.
AL833682 mRNA. Translation: CAI46154.1. Different initiation.
CCDSiCCDS42894.1.
RefSeqiNP_848552.1. NM_178457.2.
XP_005260329.1. XM_005260272.1.
XP_005260330.1. XM_005260273.1.
XP_005260331.1. XM_005260274.1.
XP_006723761.1. XM_006723698.1.
UniGeneiHs.473204.

Genome annotation databases

EnsembliENST00000371030; ENSP00000360069; ENSG00000124203.
GeneIDi128611.
KEGGihsa:128611.
UCSCiuc002yan.3. human.

Polymorphism databases

DMDMi160370001.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL121919 Genomic DNA. Translation: CAI21544.2 .
AL713683 mRNA. Translation: CAD28487.1 .
AL833682 mRNA. Translation: CAI46154.1 . Different initiation.
CCDSi CCDS42894.1.
RefSeqi NP_848552.1. NM_178457.2.
XP_005260329.1. XM_005260272.1.
XP_005260330.1. XM_005260273.1.
XP_005260331.1. XM_005260274.1.
XP_006723761.1. XM_006723698.1.
UniGenei Hs.473204.

3D structure databases

ProteinModelPortali Q5JPB2.
SMRi Q5JPB2. Positions 142-190.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9606.ENSP00000360069.

PTM databases

PhosphoSitei Q5JPB2.

Polymorphism databases

DMDMi 160370001.

Proteomic databases

PaxDbi Q5JPB2.
PRIDEi Q5JPB2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000371030 ; ENSP00000360069 ; ENSG00000124203 .
GeneIDi 128611.
KEGGi hsa:128611.
UCSCi uc002yan.3. human.

Organism-specific databases

CTDi 128611.
GeneCardsi GC20P057766.
HGNCi HGNC:16167. ZNF831.
HPAi HPA016839.
neXtProti NX_Q5JPB2.
PharmGKBi PA162410774.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG331219.
HOGENOMi HOG000231308.
HOVERGENi HBG080221.
InParanoidi Q5JPB2.
OMAi SPGKVRN.
OrthoDBi EOG769ZHP.
PhylomeDBi Q5JPB2.
TreeFami TF338213.

Miscellaneous databases

GenomeRNAii 128611.
NextBioi 82396.
PROi Q5JPB2.

Gene expression databases

Bgeei Q5JPB2.
CleanExi HS_ZNF831.
Genevestigatori Q5JPB2.

Family and domain databases

Gene3Di 3.30.160.60. 2 hits.
InterProi IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view ]
SMARTi SM00355. ZnF_C2H2. 2 hits.
[Graphical view ]
PROSITEi PS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence and comparative analysis of human chromosome 20."
    Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
    , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
    Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 379-1677.
    Tissue: Lymph node.
  3. Cited for: VARIANT HIS-1615.

Entry informationi

Entry nameiZN831_HUMAN
AccessioniPrimary (citable) accession number: Q5JPB2
Secondary accession number(s): Q5TDR4, Q8TCP0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: October 23, 2007
Last modified: July 9, 2014
This is version 77 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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