Q5JM82 (MT2B_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Metallothionein-like protein 2B

Alternative name(s):
Class I metallothionein-like protein 2B
OsMT-I-2b
OsMT2c

Gene names

Name:	MT2B
Synonyms:	RICMT
Ordered Locus Names:	Os01g0974200, LOC_Os01g74300
ORF Names:	P0698H10.31-1

Organism

Oryza sativa subsp. japonica (Rice) [Reference proteome]

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza › Oryza sativa

Protein attributes

Sequence length	80 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Metallothioneins have a high content of cysteine residues that bind various heavy metals.
Tissue specificity	Highly expressed in stems. Expressed in leaves and rachis. Ref.1 Ref.6
Induction	By heavy metals. Ref.1
Sequence similarities	Belongs to the metallothionein superfamily. Type 15 family.

Ontologies

Keywords
Ligand	Metal-binding Metal-thiolate cluster
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 80	80	Metallothionein-like protein 2B		PRO_0000263056

Sequences

	Sequence		Length	Mass (Da)
	Q5JM82 [UniParc]. Last modified February 15, 2005. Version 1. Checksum: C4C9FBD71B9F8AAA	FASTA	80	7,601
	10 20 30 40 50 60 MSCCGGNCGC GSSCQCGNGC GGCKYSEVEP TTTTTFLADA TNKGSGAASG GSEMGAENGS 70 80 CGCNTCKCGT SCGCSCCNCN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A novel MT gene of rice plants is strongly expressed in the node portion of the stem." Yu L.H., Umeda M., Liu J.-Y., Zhao N.M., Uchimiya H. Gene 206:29-35(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, INDUCTION.
[2]	"Genomic sequence of the rice metallothionein." Uchimiya H. Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]	"The genome sequence and structure of rice chromosome 1." Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T. Nature 420:312-316(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[4]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[5]	"The rice annotation project database (RAP-DB): 2008 update." The rice annotation project (RAP) Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract] Cited for: GENOME REANNOTATION. Strain: cv. Nipponbare.
[6]	"Molecular analyses of the metallothionein gene family in rice (Oryza sativa L.)." Zhou G., Xu Y., Li J., Yang L., Liu J.-Y. J. Biochem. Mol. Biol. 39:595-606(2006) [PubMed] [Europe PMC] [Abstract] Cited for: GENE FAMILY, TISSUE SPECIFICITY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB002820 mRNA. Translation: BAA19661.1. AB041032 Genomic DNA. Translation: BAB40583.1. AP003298 Genomic DNA. Translation: BAD87425.1. AP003627 Genomic DNA. Translation: BAD87835.1. AP008207 Genomic DNA. Translation: BAF07466.1.
PIR	T03404.
RefSeq	NP_001045552.1. NM_001052087.1.
UniGene	Os.20391.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	39947.LOC_Os01g74300.1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4326409.
KEGG	osa:4326409.
Organism-specific databases
Gramene	Q5JM82.
Phylogenomic databases
OMA	CKYSEVE.
ProtClustDB	CLSN2919148.
Family and domain databases
InterPro	IPR000347. Metalthion_15p. [Graphical view]
Pfam	PF01439. Metallothio_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MT2B_ORYSJ

Accession

Primary (citable) accession number: Q5JM82
Secondary accession number(s): O04107

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 12, 2006
Last sequence update:	February 15, 2005
Last modified:	April 3, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program