Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cyclin-dependent kinase C-2

Gene

CDKC-2

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei54ATPPROSITE-ProRule annotation1
Active sitei164Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi31 – 39ATPPROSITE-ProRule annotation9

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-OSA-674695. RNA Polymerase II Pre-transcription Events.

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinase C-2 (EC:2.7.11.22, EC:2.7.11.23)
Short name:
CDKC;2
Gene namesi
Name:CDKC-2
Synonyms:CDKC1
Ordered Locus Names:Os01g0958000, LOC_Os01g72790
ORF Names:OJ1294_F06.25, OsJ_04825Imported
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryza
Proteomesi
  • UP000059680 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002961011 – 513Cyclin-dependent kinase C-2Add BLAST513

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei35PhosphothreonineBy similarity1
Modified residuei36PhosphotyrosineBy similarity1
Modified residuei191PhosphoserineBy similarity1
Modified residuei198PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ5JK68.
PRIDEiQ5JK68.

Expressioni

Inductioni

Down-regulated by cytokinin.1 Publication

Gene expression databases

ExpressionAtlasiQ5JK68. baseline and differential.
GenevisibleiQ5JK68. OS.

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os01g72790.1.

Structurei

3D structure databases

ProteinModelPortaliQ5JK68.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 325Protein kinasePROSITE-ProRule annotationAdd BLAST301

Sequence similaritiesi

Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0600. Eukaryota.
ENOG410XPIR. LUCA.
HOGENOMiHOG000233024.
InParanoidiQ5JK68.
OMAiRAGIMHR.
OrthoDBiEOG093607V4.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5JK68-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVAAPGQLN LDESPSWGSR SVDCFEKLEQ IGEGTYGQVY MAKETETNEI
60 70 80 90 100
VALKKIRMDN EREGFPITAI REIKILKKLH HQNVIQLKEI VTSPGPERDE
110 120 130 140 150
QGKPIEGNKY KGSIYMVFEY MDHDLTGLAD RPGMRFTVPQ IKCYMRQLLT
160 170 180 190 200
GLHYCHVNQV LHRDIKGSNL LIDNEGNLKL ADFGLARSFS SDHNGNLTNR
210 220 230 240 250
VITLWYRPPE LLLGSTRYGP AVDMWSVGCI FAELLNGKPI LTGKNEPEQL
260 270 280 290 300
SKIFELCGTP DELIWPGVTK MPWYNNFKPQ RPMKRRVKES FKHFDQHALD
310 320 330 340 350
LLEKMLTLDP SQRISAKDAL DAEYFWTDPL PCDPKSLPKY EASHEFQTKK
360 370 380 390 400
KRQQQRQAEE AAKRQKLQHP PPHSRLPPIQ NPGQPHQIRP GQPMHNAPPV
410 420 430 440 450
AAGPSHHYAK PRGPGGPNRY PQGGNQGGYN PNRGGQGGGY GSGPYPQQGR
460 470 480 490 500
GPPPYPGGGM GGAGGPRGGG GSGYGVGGPN YQQGGPYGAS GPGRGPNYNQ
510
GGSRNQQQYG NWQ
Length:513
Mass (Da):56,826
Last modified:February 15, 2005 - v1
Checksum:i77BFC08EF38E1D96
GO

Sequence cautioni

The sequence CAD54641 differs from that shown. Reason: Frameshift at position 309.Curated
The sequence CAD92448 differs from that shown. Reason: Frameshift at position 309.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ512410 mRNA. Translation: CAD54641.1. Frameshift.
AJ564977 mRNA. Translation: CAD92448.1. Frameshift.
AP004326 Genomic DNA. Translation: BAD88154.1.
AP008207 Genomic DNA. Translation: BAF07364.1.
AP014957 Genomic DNA. Translation: BAS76301.1.
CM000138 Genomic DNA. Translation: EEE56036.1.
UniGeneiOs.14473.
Os.26898.

Genome annotation databases

EnsemblPlantsiOS01T0958000-01; OS01T0958000-01; OS01G0958000.
GrameneiOS01T0958000-01; OS01T0958000-01; OS01G0958000.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ512410 mRNA. Translation: CAD54641.1. Frameshift.
AJ564977 mRNA. Translation: CAD92448.1. Frameshift.
AP004326 Genomic DNA. Translation: BAD88154.1.
AP008207 Genomic DNA. Translation: BAF07364.1.
AP014957 Genomic DNA. Translation: BAS76301.1.
CM000138 Genomic DNA. Translation: EEE56036.1.
UniGeneiOs.14473.
Os.26898.

3D structure databases

ProteinModelPortaliQ5JK68.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi39947.LOC_Os01g72790.1.

Proteomic databases

PaxDbiQ5JK68.
PRIDEiQ5JK68.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiOS01T0958000-01; OS01T0958000-01; OS01G0958000.
GrameneiOS01T0958000-01; OS01T0958000-01; OS01G0958000.

Phylogenomic databases

eggNOGiKOG0600. Eukaryota.
ENOG410XPIR. LUCA.
HOGENOMiHOG000233024.
InParanoidiQ5JK68.
OMAiRAGIMHR.
OrthoDBiEOG093607V4.

Enzyme and pathway databases

ReactomeiR-OSA-674695. RNA Polymerase II Pre-transcription Events.

Gene expression databases

ExpressionAtlasiQ5JK68. baseline and differential.
GenevisibleiQ5JK68. OS.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCDKC2_ORYSJ
AccessioniPrimary (citable) accession number: Q5JK68
Secondary accession number(s): B9EWJ5, Q5K4U5, Q7Y0V2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: February 15, 2005
Last modified: November 30, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.