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Q5JK68 (CDKC2_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cyclin-dependent kinase C-2
Short name=CDKC;2
EC=2.7.11.22
EC=2.7.11.23
Gene names
Name:CDKC-2
Synonyms:CDKC1
Ordered Locus Names:Os01g0958000, LOC_Os01g72790
ORF Names:OJ1294_F06.25
OrganismOryza sativa subsp. japonica (Rice) [Reference proteome]
Taxonomic identifier39947 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza ›

Protein attributes

Sequence length513 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

Induction

Down-regulated by cytokinin. Ref.5

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Contains 1 protein kinase domain.

Sequence caution

The sequence CAD54641.1 differs from that shown. Reason: Frameshift at position 309.

The sequence CAD92448.1 differs from that shown. Reason: Frameshift at position 309.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 513513Cyclin-dependent kinase C-2
PRO_0000296101

Regions

Domain25 – 325301Protein kinase
Nucleotide binding31 – 399ATP By similarity

Sites

Active site1641Proton acceptor By similarity
Binding site541ATP By similarity

Amino acid modifications

Modified residue351Phosphothreonine By similarity
Modified residue361Phosphotyrosine By similarity
Modified residue1911Phosphoserine By similarity
Modified residue1981Phosphothreonine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5JK68 [UniParc].

Last modified February 15, 2005. Version 1.
Checksum: 77BFC08EF38E1D96

FASTA51356,826
        10         20         30         40         50         60 
MAVAAPGQLN LDESPSWGSR SVDCFEKLEQ IGEGTYGQVY MAKETETNEI VALKKIRMDN 

        70         80         90        100        110        120 
EREGFPITAI REIKILKKLH HQNVIQLKEI VTSPGPERDE QGKPIEGNKY KGSIYMVFEY 

       130        140        150        160        170        180 
MDHDLTGLAD RPGMRFTVPQ IKCYMRQLLT GLHYCHVNQV LHRDIKGSNL LIDNEGNLKL 

       190        200        210        220        230        240 
ADFGLARSFS SDHNGNLTNR VITLWYRPPE LLLGSTRYGP AVDMWSVGCI FAELLNGKPI 

       250        260        270        280        290        300 
LTGKNEPEQL SKIFELCGTP DELIWPGVTK MPWYNNFKPQ RPMKRRVKES FKHFDQHALD 

       310        320        330        340        350        360 
LLEKMLTLDP SQRISAKDAL DAEYFWTDPL PCDPKSLPKY EASHEFQTKK KRQQQRQAEE 

       370        380        390        400        410        420 
AAKRQKLQHP PPHSRLPPIQ NPGQPHQIRP GQPMHNAPPV AAGPSHHYAK PRGPGGPNRY 

       430        440        450        460        470        480 
PQGGNQGGYN PNRGGQGGGY GSGPYPQQGR GPPPYPGGGM GGAGGPRGGG GSGYGVGGPN 

       490        500        510 
YQQGGPYGAS GPGRGPNYNQ GGSRNQQQYG NWQ

« Hide

References

« Hide 'large scale' references
[1]"Identification of a novel developmentally regulated C type cyclin-dependent kinase in rice plants."
Huang Y.W., Huang H.J.
Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"The genome sequence and structure of rice chromosome 1."
Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y., Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H., Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M. expand/collapse author list , Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S., Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H., Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y., Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S., Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y., Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H., Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.
Nature 420:312-316(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[3]"The map-based sequence of the rice genome."
International rice genome sequencing project (IRGSP)
Nature 436:793-800(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Nipponbare.
[4]"The rice annotation project database (RAP-DB): 2008 update."
The rice annotation project (RAP)
Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: GENOME REANNOTATION.
Strain: cv. Nipponbare.
[5]"Genome-wide identification and expression analysis of rice cell cycle genes."
Guo J., Song J., Wang F., Zhang X.S.
Plant Mol. Biol. 64:349-360(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: INDUCTION, GENE FAMILY.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AJ512410 mRNA. Translation: CAD54641.1. Frameshift.
AJ564977 mRNA. Translation: CAD92448.1. Frameshift.
AP004326 Genomic DNA. Translation: BAD88154.1.
AP008207 Genomic DNA. Translation: BAF07364.1.
RefSeqNP_001045450.1. NM_001051985.1.
UniGeneOs.14473.

3D structure databases

HSSPHSSP built from PDB template 1OIT based on UniProtKB P24941.
ProteinModelPortalQ5JK68.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsLOC_Os01g72790.1; LOC_Os01g72790.1; LOC_Os01g72790.
GeneID4325386.
KEGGdosa:Os01t0958000-01.
osa:4325386.

Organism-specific databases

GrameneQ5JK68.

Phylogenomic databases

eggNOGCOG0515.
HOGENOMHOG000233024.
KOK08819.
OMAYEASHEF.
ProtClustDBCLSN2692317.

Gene expression databases

ArrayExpressQ5JK68.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_cat_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. Kinase_like. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCDKC2_ORYSJ
AccessionPrimary (citable) accession number: Q5JK68
Secondary accession number(s): Q5K4U5, Q7Y0V2
Entry history
Integrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: February 15, 2005
Last modified: May 1, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents