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Protein

Cyclin-dependent kinase C-2

Gene

CDKC-2

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.
ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei54ATPPROSITE-ProRule annotation1
Active sitei164Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi31 – 39ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-OSA-674695 RNA Polymerase II Pre-transcription Events
R-OSA-6796648 TP53 Regulates Transcription of DNA Repair Genes
R-OSA-6798695 Neutrophil degranulation
R-OSA-9018519 Estrogen-dependent gene expression

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-dependent kinase C-2 (EC:2.7.11.22, EC:2.7.11.23)
Short name:
CDKC;2
Gene namesi
Name:CDKC-2
Synonyms:CDKC1
Ordered Locus Names:Os01g0958000, LOC_Os01g72790
ORF Names:OJ1294_F06.25, OsJ_04825Imported
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladeOryzoideaeOryzeaeOryzinaeOryzaOryza sativa
Proteomesi
  • UP000059680 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002961011 – 513Cyclin-dependent kinase C-2Add BLAST513

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei35PhosphothreonineBy similarity1
Modified residuei36PhosphotyrosineBy similarity1
Modified residuei191PhosphoserineBy similarity1
Modified residuei198PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ5JK68
PRIDEiQ5JK68

Expressioni

Inductioni

Down-regulated by cytokinin.1 Publication

Gene expression databases

ExpressionAtlasiQ5JK68 differential
GenevisibleiQ5JK68 OS

Interactioni

Protein-protein interaction databases

STRINGi39947.LOC_Os01g72790.1

Structurei

3D structure databases

ProteinModelPortaliQ5JK68
SMRiQ5JK68
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 325Protein kinasePROSITE-ProRule annotationAdd BLAST301

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0600 Eukaryota
ENOG410XPIR LUCA
HOGENOMiHOG000233024
InParanoidiQ5JK68
OMAiKDPTGCD
OrthoDBiEOG093607V4

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

Q5JK68-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVAAPGQLN LDESPSWGSR SVDCFEKLEQ IGEGTYGQVY MAKETETNEI
60 70 80 90 100
VALKKIRMDN EREGFPITAI REIKILKKLH HQNVIQLKEI VTSPGPERDE
110 120 130 140 150
QGKPIEGNKY KGSIYMVFEY MDHDLTGLAD RPGMRFTVPQ IKCYMRQLLT
160 170 180 190 200
GLHYCHVNQV LHRDIKGSNL LIDNEGNLKL ADFGLARSFS SDHNGNLTNR
210 220 230 240 250
VITLWYRPPE LLLGSTRYGP AVDMWSVGCI FAELLNGKPI LTGKNEPEQL
260 270 280 290 300
SKIFELCGTP DELIWPGVTK MPWYNNFKPQ RPMKRRVKES FKHFDQHALD
310 320 330 340 350
LLEKMLTLDP SQRISAKDAL DAEYFWTDPL PCDPKSLPKY EASHEFQTKK
360 370 380 390 400
KRQQQRQAEE AAKRQKLQHP PPHSRLPPIQ NPGQPHQIRP GQPMHNAPPV
410 420 430 440 450
AAGPSHHYAK PRGPGGPNRY PQGGNQGGYN PNRGGQGGGY GSGPYPQQGR
460 470 480 490 500
GPPPYPGGGM GGAGGPRGGG GSGYGVGGPN YQQGGPYGAS GPGRGPNYNQ
510
GGSRNQQQYG NWQ
Length:513
Mass (Da):56,826
Last modified:February 15, 2005 - v1
Checksum:i77BFC08EF38E1D96
GO

Sequence cautioni

The sequence CAD54641 differs from that shown. Reason: Frameshift at position 309.Curated
The sequence CAD92448 differs from that shown. Reason: Frameshift at position 309.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ512410 mRNA Translation: CAD54641.1 Frameshift.
AJ564977 mRNA Translation: CAD92448.1 Frameshift.
AP004326 Genomic DNA Translation: BAD88154.1
AP008207 Genomic DNA Translation: BAF07364.1
AP014957 Genomic DNA Translation: BAS76301.1
CM000138 Genomic DNA Translation: EEE56036.1
UniGeneiOs.14473
Os.26898

Genome annotation databases

EnsemblPlantsiOs01t0958000-01; Os01t0958000-01; Os01g0958000
Os01t0958000-02; Os01t0958000-02; Os01g0958000
GrameneiOs01t0958000-01; Os01t0958000-01; Os01g0958000
Os01t0958000-02; Os01t0958000-02; Os01g0958000

Similar proteinsi

Entry informationi

Entry nameiCDKC2_ORYSJ
AccessioniPrimary (citable) accession number: Q5JK68
Secondary accession number(s): B9EWJ5, Q5K4U5, Q7Y0V2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 24, 2007
Last sequence update: February 15, 2005
Last modified: May 23, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families
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